Miami Marlins vs San Diego Padres Prediction 5/27/25 MLB Picks

In this article, we will formulate a Marlins vs Padres prediction for this MLB game on Tuesday, May 27, at PETCO Park in San Diego, California. Let’s take a look at the prediction for this MLB matchup.

Miami Marlins Betting Preview

The Miami Marlins (21-31, 8-16 Away) responded to a three-game losing skid with a couple of wins over the Los Angeles Angels to win the series after losing Game 1. The Marlins returned to losing ways in San Diego after they narrowly lost 4-3 in extra innings to the Padres in the opening game of the current series. Ryan Wathers pitched for 5.2 innings in a no-decision, allowing two runs (none earned) on three hits with six strikeouts and three walks. Cade Gibson took the loss.

This season, the Marlins average 4.10 runs per game (20th in the MLB) on a .249/.314/.387 triple-slash. When it comes to pitching, the Marlins’ staff has a 5.21 ERA (27th) and 1.44 WHIP (26th). Kyle Stowers leads the Marlins with a .300 batting average, ten home runs, and 31 RBI this season.

Max Meyer will take the mound for the Marlins on Tuesday. The 26-year-old right-hander has a 3-4 record in ten starts this year with a 4.15 ERA and 1.28 WHIP in 56.1 innings.

San Diego Padres Betting Preview

The San Diego Padres (30-22, 17-8 Home) suffered a series sweep at the hands of the Mariners and Blue Jays and were on a six-game losing skid, their longest of the season. San Diego responded with a series win over the Braves and then opened this series against the Marlins with a 4-3 win. On Monday, Jose Iglesias led the team with two RBI, while Randy Vasquez pitched for 6.1 innings in a no-decision, allowing three runs on six hits with five strikeouts and one walk. Adrian Morejon was credited with the win.

This year, the Padres average 4.17 runs per game (17th in the MLB) on a .251/.317/.388 triple-slash. When it comes to pitching, the Padres’ staff has a 3.49 ERA (9th) and 1.19 WHIP (8th). Gavin Sheets leads the Padres with a .274 batting average, ten home runs, and 31 RBI this season.

The projected starting pitcher for the Padres is Stephen Kolek, who is 2-1 in four starts this season, with a 2.84 ERA and 1.26 WHIP in 25.1 innings.

Total Runs Facts

• Each of the Padres’ last five home games have gone UNDER the total runs line.
• Each of the Marlins’ last four games after going to extra innings have gone OVER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in 10 of the Padres’ last 11 games as favorites against NL East opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Marlins’ last five night games against NL West opponents.

Matchup/League Facts

• The Padres rank 3rd in the league for hits allowed this season (381).
• The Padres rank T23rd in the league for RBIs this season (198).
• The Marlins rank 26th in the league for walks allowed this season (200).
• The Marlins rank 25th in the league for opponent batting average this season (.260).

Marlins vs Padres Prediction

The Padres won seven of the previous ten H2H encounters, including three of the last four. Three of the last five H2H duels went Over, and I am going with another Over here because I don’t trust these starters. Max Meyer allowed 19 runs in his last five starts, while he allowed a .353 BA in 17 at-bats against the Padres in his career. Stephen Kolek, on the other hand, surrendered eight runs in two starts following his complete-game shutout against Colorado. He will allow multiple runs again in this one. Back the Over.