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Giants vs Tigers Prediction 5/27/25 MLB Picks

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Detroit Tigers (35-20) vs San Francisco Giants (31-23)

May 27, 2025 at 06:40 PM EDT

The Line: Betting Odds: Detroit Tigers -102 / San Francisco Giants -118 — Over/Under: 6.5

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In this article, we will formulate a Giants vs Tigers prediction for this MLB game on Tuesday, May 27th at Comerica Park in Detroit, Michigan. Let’s take a look at the prediction for this MLB matchup. 

San Francisco Giants Betting Preview

The San Francisco Giants are 31-23 this year after they lost game one by a score of 3-1 on Monday afternoon. San Francisco cut the deficit to 3-1 in the sixth inning, but couldn’t get any closer in the loss. The Giants recorded five hits and they committed one error in the game, while they were led by Flores, who went 2-4 with one RBI in the loss. SF started Birdsong, who allowed five hits and three earned runs over 4.1 innings for the loss, while Miller, Bivens, and Hicks finished the final 3.2 innings. 

Prior to this series, the Giants won two out of three against the Nationals, but lost two out of three against the Royals before that. San Francisco has alternated wins and losses over their last eight games, and they are currently second in the NL West standings. The San Francisco pitching staff has a 3.25 ERA with a 1.21 WHIP, and a .234 opponent batting average, while the offense has scored 238 runs with a .231 batting average and a .308 on-base percentage this season. Wilmer Flores has led San Francisco with 10 home runs and 44 RBIs, while Matt Chapman has added nine home runs and 25 RBIs this year. The projected starting pitcher for San Francisco is Logan Webb, who is 5-4 with a 2.67 ERA and a 1.20 WHIP over 67.1 innings pitched this year. 

Detroit Tigers Betting Preview

The Detroit Tigers are 35-20 this season after they won game one in this series on Monday afternoon. Detroit scored the first three runs in the game, and they were able to get the win, despite not scoring over the final four innings. The Tigers recorded seven hits in the game, and they were led by Greene, who went 1-4 with two RBIs in the win. Detroit started Montero, who allowed one hit and zero earned runs over 5.0 innings for the win, while Vest picked up the save. 

Prior to this series, the Tigers lost three out of four against the Guardians, but did win two out of three against the Cardinals before that. Detroit has won four of its last seven games, and they are currently first in the AL Central standings. The Detroit pitching staff has a 3.27 ERA with a 1.16 WHIP and a .224 opponent batting average, while the offense has scored 281 runs with a .253 batting average and a .326 on-base percentage this season. Spencer Torkelson has led Detroit with 13 home runs and 40 RBIs, while Riley Greene has added 12 home runs and 36 RBIs this year. The projected starting pitcher for Detroit is Jack Flaherty, who is 2-6 with a 4.39 ERA and a 1.18 WHIP over 53.1 innings pitched this season. 

Why the Giants will beat the Tigers 

  • The Giants have won each of their last four night games following a loss.
  • The Tigers have lost each of their last six Tuesday night games against NL West opponents that held a winning record.
  • The Tigers have failed to cover the run line each of their last six night games against teams that held a winning record.
  • The Giants have covered the run line in four of their last five night games following a loss.
  • The Giants have led after 5 innings in four of their last five road games against AL Central opponents that held a winning record.

Total Runs Facts

  • Eight of the Giants’ last nine games have gone UNDER the total runs line.
  • Six of the Tigers’ last seven night games against NL West opponents have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Giants’ last five night games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in six of the Tigers’ last seven games as underdogs.

Detroit Tigers Player Prop Facts

  • Colt Keith has recorded a Double in four of his last five appearances.
  • Gleyber Torres has recorded at least one RBI in four of the Tigers’ last five games against NL West opponents.
  • Riley Greene has scored at least one run in each of the Tigers’ last four games as home underdogs.
  • Riley Greene has recorded at least one Single in eight of the Tigers’ last nine games against NL West opponents at Comerica Park.
  • Jack Flaherty has recorded six or more strikeouts in six of his last seven home appearances.
  • Riley Greene has recorded at least one hit in each of the Tigers’ last 10 games as underdogs.
  • Andy Ibanez has hit a home run in two of the Tigers’ last three games as home underdogs against NL West opponents.

San Francisco Giants Player Prop Facts

  • Logan Webb has recorded six or more strikeouts in each of his last four appearances with the Giants as road favorites.
  • Heliot Ramos has recorded at least one Single in each of the Giants’ last 10 games as favorites against AL opponents.
  • Wilmer Flores has recorded an RBI in each of the Giants’ last three road games against opponents that held a winning record.
  • Tom Murphy has recorded a Double in each of his last three road appearances against AL Central opponents that held a winning record.
  • Heliot Ramos has recorded at least one hit in each of his last 11 appearances against AL opponents.
  • Matt Chapman has scored at least one run in each of the Giants’ last four road games against opponents that held a winning record.
  • Heliot Ramos has hit a home run in each of his last two road appearances against AL Central opponents.

Giants vs Tigers Prediction 

San Francisco failed to win back-to-back games on Monday afternoon, and their trend continues, as they have alternated wins and losses over their last eight games. The Giants are 14-14 on the road this year, while the Tigers are 19-8 at home. Detroit has won two games in a row, but its offense hasn’t been right over the last week or so. The Tigers are starting Flaherty, who has allowed three earned runs or more in four of his last five starts. The Giants are going with Webb, who has allowed two earned runs or fewer in three of his last four outings. Take the Giants here, especially with the Detroit bats cooling off. 

David Racey's Pick: Giants ML

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