St. Louis Cardinals vs Washington Nationals Prediction 5/11/25 MLB Picks

Washington Nationals Betting Preview

The Washington Nationals are 17-23 on the year and play the Braves, Orioles, and Braves next. The Washington Nationals are batting .240 on the season, have a .310 OBP, and a .381 slugging percentage. The Washington Nationals' pitching staff has a 5.43 ERA and a 1.46 WHIP. James Wood leads the Washington Nationals with 43 hits and 23 RBI, while Keibert Ruiz and Nathaniel Lowe have combined for 74 hits and 42 RBI.

MacKenzie Gore gets the ball for the Washington Nationals, and he is 2-3 with a 3.33 ERA and 68 strikeouts this season. Gore is 0-1 with a 10.05 ERA and 16 strikeouts in his career against the St. Louis Cardinals.

Why the Washington Nationals will win

• The Cardinals have lost nine of their last 11 road games after playing the previous day.
• The Nationals have won each of their last eight Sunday day games as home favorites against National League opponents.
• The favorites have covered the run line in each of the Nationals' last four games at Nationals Park.
• The Cardinals have failed to cover the run line in seven of their last nine day games following a win.

Why the St. Louis Cardinals will win

• The Cardinals have won each of their last seven games against National League opponents.
• The Nationals have lost each of their last five home games against NL Central opponents.
• The Cardinals have covered the run line in each of their last seven games against National League opponents.
• The Nationals have failed to cover the run line in seven of their last eight games as favorites against the Cardinals following a loss.
• The Cardinals have led after 3 innings in each of their last four road games against opponents that held a losing record.
• The Cardinals have led after 5 innings in each of their last four games at Nationals Park against National League opponents that held a losing record.

Washington Nationals Player Prop Facts

• Keibert Ruiz has hit a home run in three of his last six appearances against the Cardinals after playing the previous day.
• CJ Abrams has recorded a Double in each of the Nationals' last three games against NL Central opponents.
• Josh Bell has recorded at least one RBI in each of his last three appearances with his team as a favorite against NL Central opponents.
• Josh Bell has scored at least one run in each of his last seven Sunday appearances against NL teams that held a winning record.
• Josh Bell has recorded a Single in each of his last seven appearances with the Nationals as home favorites.
• MacKenzie Gore has recorded seven or more strikeouts in each of his last four home appearances.
• Josh Bell has recorded at least one hit in each of his last 12 appearances with his team as a favorite against NL Central opponents.
• James Wood ranks T7th in the league in Home Runs (10) this season.

St. Louis Cardinals Player Prop Facts

• Miles Mikolas has recorded a win in four of his last five appearances at Nationals Park.
• Brendan Donovan has recorded a Double in each of the Cardinals' last three games at Nationals Park against NL East opponents that held a losing record.
• Willson Contreras has hit a home run in three of the Cardinals' last seven games against NL East opponents that held a losing record.
• Nolan Gorman has scored at least one run in seven of his last eight appearances in day games against NL East teams that held a losing record.
• Willson Contreras has recorded at least one RBI in four of the Cardinals' last five games as underdogs against NL opponents.
• Brendan Donovan has recorded at least one hit in each of his last 15 appearances against NL opponents that held a losing record.
• Masyn Winn has recorded at least one Single in each of his last seven road appearances against NL East opponents.

St. Louis Cardinals vs Washington Nationals Prediction

You can make a case for the Nationals, as Gore has been solid this season with a top-40 ERA and WHIP, and he leads baseball in strikeouts. The problem is that the Nats have scored two or fewer runs in three of their last four games. 

The Cardinals have won seven straight games, and they’re rolling with their lineup and pitching staff. The Cardinals have allowed a combined two runs in their last three games. Mikolas has allowed a combined 13 hits and three runs in his last 16.1 innings, easily his best stretch of the season. Also, Gore is allowing a .463 batting average and a .500 on-base percentage in 41 at-bats against current Cardinals’ hitters. I’m just not trying to step in front of the Cardinals in their current form. I'm not sure how the Cardinals are underdogs in this spot. I'll gladly take the plus money and the hottest team in baseball.