Cincinnati Reds vs Houston Astros Prediction 5/11/25 MLB Picks

Houston Astros (19-19) vs Cincinnati Reds (20-21)

Game Info: Sunday, May 11, 2025 at 2:10 pm (Daikin Park)

C. Petty (R) vs R. Blanco (R)

Betting Odds: Houston Astros -155 / Cincinnati Reds +130 --- Over/Under: 8.5 Click Here for the Latest Odds

Where to Watch: MLB.TV

The Cincinnati Reds and Houston Astros meet Sunday in MLB action at Daikin Park. Here’s a Cincinnati Reds vs Houston Astros Prediction. This article will include a Cincinnati Reds vs Houston Astros Pick.

Cincinnati Reds Betting Preview

The Cincinnati Reds are 20-21 on the year and play the White Sox, Guardians, and Pirates next. The Cincinnati Reds are batting .242 on the season, have a .325 OBP, and a .383 slugging percentage. The Cincinnati Reds pitching staff has a 3.71 ERA and a 1.16 WHIP. TJ Friedl leads the Cincinnati Reds with 43 hits and 17 RBI, while Elly De La Cruz and Gavin Lux have combined for 77 hits and 47 RBI. 

Chase Petty gets the ball for the Cincinnati Reds, and he is 0-1 with a 34.71 ERA and 3 strikeouts this season. This will be Petty’s first career game against the Houston Astros.

Houston Astros Betting Preview

The Houston Astros are 19-19 on the year and play the Royals, Rangers, and Rays next. The Houston Astros are batting .247 on the season, have a .318 OBP, and a .375 slugging percentage. The Houston Astros' pitching staff has a 3.53 ERA and a 1.16 WHIP. Jeremy Pena leads the Houston Astros with 42 hits and 19 RBI, while Jose Altuve and Isaac Paredes have combined for 74 hits and 31 RBI.

Ronel Blanco gets the ball for the Houston Astros, and he is 2-3 with a 4.98 ERA and 32 strikeouts this season. This will be Blanco’s second career game against the Cincinnati Reds.

Why the Houston Astros will win

  • The Astros have won seven of their last eight day games following a loss.
  • The Reds have lost four of their last five road games against American League opponents following a road win.
  • The Astros have covered the run line in seven of their last eight day games following a loss.
  • The Reds have failed to cover the run line in four of their last five road games against American League opponents following a road win.
  • The Reds have trailed after 5 innings in three of their last four games against AL West opponents.

Why the Cincinnati Reds will win

  • The Reds have won each of their last nine games against the Astros following a win.
  • The Astros have lost each of their last eight games against the Reds following a loss.
  • The Reds have covered the run line in each of their last seven day games against AL West opponents following a win.
  • The Astros have failed to cover the run line each of their last six day games against NL Central opponents that held a losing record.

Houston Astros Player Prop Facts

  • Brendan Rodgers has recorded a Double in five of his six previous home appearances against the Reds.
  • Victor Caratini has hit a home run in each of his last two appearances at Daikin Park.
  • Isaac Paredes has recorded an RBI in each of the Astros' last four games as favorites against NL Central opponents.
  • Victor Caratini has scored at least one run in seven of his last eight appearances in day games.
  • Jeremy Pena has recorded at least one hit in each of the Astros' last 14 games at Daikin Park.
  • Jeremy Pena has recorded at least one Single in each of the Astros' last eight games at Daikin Park.

Cincinnati Reds Player Prop Facts

  • Will Benson has scored a run in each of his four previous road appearances against the Astros.
  • Tyler Stephenson has recorded at least one hit in each of his last nine appearances against AL West opponents.
  • Austin Hays has recorded at least one Single in eight of his last nine appearances with his team as an underdog.
  • Jose Trevino has recorded a Double in four of his last five appearances against AL opponents.
  • Jake Fraley has hit a home run in two of his last three appearances against AL opponents.
  • Austin Hays has recorded at least one RBI in five of his last six appearances in day games.

Cincinnati Reds vs Houston Astros Prediction

The Reds have had issues stringing together wins lately, and I’m not running to the window to back Petty, who has just 2.1 innings under his belt. Petty was rocked in his MLB debut against the Cardinals, allowing seven hits and nine runs while getting just one ground ball. The Astros and Blanco aren’t lighting the world on fire, as he’s allowed 30 hits and 19 runs in 34.1 innings. Still, we saw Blanco have a strong season last year, and he’s been solid at home this season, posting a 3.74 ERA and .173 allowed batting average in 21.2 innings. The Astros should win this game. Give me the home team and a reasonable price.

Randy’s Pick Houston Astros -155

Get Premium Picks Start Winning Now »
The pick in this article is the opinion of the writer, not a PickDawgz site consensus.

18+ Has gambling become a problem for you? Call the National Problem Gambling Hotline.
1-800-522-4700 | ncpgambling.org

Credit Guaranteed Packages

Packages with Credit Guarantees automatically give you a credit if the package does not turn a profit—the sum of betting all individual picks. THESE ARE NOT PARLAYS UNLESS OTHERWISE CLEARLY STATED. If a credit guaranteed package does not profit, a credit for its full purchase price is automatically issued after picks are graded and verified.

For example, if you purchase a $39.95 package that doesn’t profit, you’ll get a $39.95 credit towards any future purchase(s) on our site. Credits are usually issued within hours of a game’s conclusion, so please allow a few hours for final verification.

To use your credits, log in to your account and add another package or pass to your cart. Credits will automatically reduce what you owe. Any remaining balance will be settled through our payment system, with any leftover credits available future purchases. Credits do not expire.

Dismiss