San Diego Padres vs New York Yankees Prediction 5/5/25 MLB Picks

In this article, we will formulate a Padres vs Yankees prediction for this MLB game on Monday, May 5, at Yankee Stadium in Bronx, New York. Let’s take a look at the prediction for this MLB matchup.

San Diego Padres Betting Preview

The San Diego Padres (22-11, 8-7 Away) responded to a four-game losing skid with five consecutive wins. The Padres swept the Giants in a two-game series and then swept the Pirates in three games. In the most recent 4-0 win over Pittsburgh, Xander Bogaerts led the offense with three RBI, while Stephen Kolek got the win after allowing no runs on four hits with four strikeouts and two walks in 5.1 innings.

This season, the Padres average 4.03 runs per game (18th in the MLB) on a .260/.329/.393 slash line. Regarding pitching, the Padres’ staff has a 2.75 ERA (1st) and 1.14 WHIP (4th). Fernando Tatis Jr. leads the Padres with a .328 batting average, eight home runs, and 18 RBI this season.

The projected starting pitcher for the Padres is Nick Pivetta, who is 5-1 in six starts this season, with a 1.78 ERA and 0.82 WHIP in 35.1 innings.

New York Yankees Betting Preview

The New York Yankees (19-15, 11-7 Home) lost two series against the Orioles and Rays in a row. After winning the opening game of the series against Tampa Bay, the Yankees suffered a couple of losses. In the latest 7-5 defeat, Cody Bellinger and Jorbit Vivas led the offense with two RBI apiece, while Will Warren took the loss after allowing five runs (three earned) on seven hits with eight strikeouts and three walks in 4.2 innings.

This year, the Yankees average 5.50 runs per game (2nd in the MLB) on a .262/.346/.470 triple-slash. When it comes to pitching, the Yankees’ staff has a 3.62 ERA (10th) and 1.20 WHIP (8th). Aaron Judge leads the Yankees with a .423 batting average, 11 home runs, and 33 RBI this season.

Carlos Rodon will take the mound for the Yankees on Monday. The 32-year-old left-hander has a 4-3 record in seven starts this year with a 3.43 ERA and 0.98 WHIP in 42.0 innings.

Total Runs Facts

• Each of the Yankees’ last seven games against National League opponents have gone OVER the total runs line.
• Seven of the Padres’ last eight road games after playing the previous day have gone UNDER the total runs line.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Yankees’ last 10 games as favorites against NL West opponents.
• The ‘Inning 1 OVER 0.5 runs’ market has hit in four of the Padres’ last five games at Yankee Stadium.

Matchup/League Facts

• The Yankees rank 1st in the league for on-base percentage this season (.346).
• The Yankees rank 1st in the league for opponent batting average this season (.205).
• The Padres rank T1st in the league for hits allowed this season (225).
• The Padres rank 1st in the league for runs allowed this season (95).

Padres vs Yankees Prediction

The Yankees won seven of the previous ten H2H encounters, including four of the last five. Five of the last seven H2Hs went under, which was the case in seven of San Diego’s previous ten games and also in seven of New York’s past ten games. Nick Pivetta is the Padres’ best pitcher so far; he shut the opponents out in three of his six starts this year, and I expect him to have another solid outing on Monday. Carlos Rodon allowed just two runs in his last three starts and had quality starts in five of the last six games. Back the Under in this one.

Oliver Zivic's Pick: Under 7.5