Minnesota Twins vs Cleveland Guardians Prediction 4/29/25 MLB Picks

Cleveland Guardians Betting Preview

The Cleveland Guardians are 15-13 on the year and play the Blue Jays, Nationals, and Phillies next. The Cleveland Guardians are batting .237 on the season, have a .306 OBP, and a .381 slugging percentage. The Cleveland Guardians' pitching staff has a 4.61 ERA and a 1.46 WHIP. Steven Kwan leads the Cleveland Guardians with 38 hits and 15 RBI, while Jose Ramirez and Gabriel Arias have combined for 49 hits and 25 RBI.

Tanner Bibee gets the ball for the Cleveland Guardians, and he is 2-2 with a 5.19 ERA and 20 strikeouts this season. Bibee is 2-0 with a 2.72 ERA and 45 strikeouts in his career against the Minnesota Twins.

Why the Cleveland Guardians will win

• The Guardians have won each of their last 10 Tuesday night games against teams that held a losing record.
• The Twins have lost seven of their last eight games against American League opponents following a road win.
• The Guardians have covered the run line in three of their last four games as favorites against AL Central opponents.

Why the Minnesota Twins will win

• The underdogs have won four of the Twins' last five games at Progressive Field.
• The Guardians have lost three of their last four games as favorites following a home loss.
• The Guardians have failed to cover the run line in each of their last eight night games against the Twins at Progressive Field following a home loss.
• The Twins have covered the run line in each of their last eight Tuesday games against American League opponents.
• The Guardians have lost the first inning in four of their last five night games against American League opponents.
• The Guardians have trailed after 5 innings in five of their last six games against American League opponents.
• The Guardians have trailed after 3 innings in five of their last six games against American League opponents.

Cleveland Guardians Player Prop Facts

• Steven Kwan has scored at least one run in seven of the Guardians' last eight Tuesday night games against AL opponents that held a losing record.
• Steven Kwan has recorded at least one Single in each of the Guardians' last six games as favorites.
• Will Brennan has recorded at least one Double in each of his last three appearances with the Guardians as favorites.
• Will Brennan has recorded at least one hit in each of his last eight appearances against the Twins.
• Lane Thomas has hit a home run in three of his last four Tuesday appearances with the Guardians as favorites.
• Lane Thomas has recorded at least one RBI in four of his last five appearances in night games against AL Central teams that held a losing record.
• Steven Kwan ranks 6th amongst qualified players for Batting Average (.345) this season.

Minnesota Twins Player Prop Facts

• Ty France has recorded a Double in each of the Twins' last three games against AL opponents.
• Byron Buxton has hit a home run in three of his last five appearances after playing the previous day.
• Ty France has scored at least one run in each of the Twins' last seven road games against AL opponents.
• Carlos Correa has recorded at least one Single in each of the Twins' last four games against AL opponents.
• Chris Paddack has recorded four or more strikeouts in each of his last seven appearances against AL opponents that held a winning record.
• Jonah Bride has recorded at least one hit in each of his last 13 road appearances against AL opponents.
• Jonah Bride has recorded at least one RBI in seven of his last eight appearances with his team as an underdog against AL opponents.

Minnesota Twins vs Cleveland Guardians Prediction

The Guardians are getting the benefit of the doubt because they’re at home with the better pitcher, but they’ve lost four of their last five games and have been shaky offensively. The Twins have quietly won six of their last seven games and are rolling with their lineup and pitching staff. Also, while Paddack has rough numbers on the season, it’s because of a bad season opener. Paddack has allowed seven earned runs in his last 19 innings while striking out 18. Paddack has allowed three or fewer earned runs in each of his last four starts. It’s only a matter of time before the Twins give him some run support. Give me the Twins and the plus money.