New York Yankees vs Baltimore Orioles Prediction 4/28/25 MLB Picks
Baltimore Orioles (10-17) vs New York Yankees (17-11)
Game Info: Monday, April 28, 2025 at 6:35 pm (Oriole Park at Camden Yards)
W. Warren (R) vs T. Sugano (R)
Betting Odds: Baltimore Orioles +102 / New York Yankees -122 --- Over/Under: 10 Click Here for the Latest Odds
Where to Watch: MLB.TV
The New York Yankees and Baltimore Orioles meet Monday in MLB action at Oriole Park at Camden Yards. Here’s a New York Yankees vs Baltimore Orioles Prediction. This article will include a New York Yankees vs Baltimore Orioles Pick.
New York Yankees Betting Preview
The New York Yankees are 17-11 on the year and play the Rays, Padres, and Athletics next. The New York Yankees are batting .262 on the season, have a .348 OBP, and a .468 slugging percentage. The New York Yankees' pitching staff has a 3.70 ERA and a 1.20 WHIP. Aaron Judge leads the New York Yankees with 43 hits and 27 RBI, while Paul Goldschmidt and Anthony Volpe have combined for 61 hits and 27 RBI.
Will Warren gets the ball for the New York Yankees, and he is 1-0 with a 4.79 ERA and 21 strikeouts this season. This will be Warren’s first career game against the Baltimore Orioles.
Baltimore Orioles Betting Preview
The Baltimore Orioles are 10-17 on the year and play the Royals, Twins, and Angels next. The Baltimore Orioles are batting .223 on the season, have a .297 OBP, and a .380 slugging percentage. The Baltimore Orioles pitching staff has a 5.37 ERA and a 1.56 WHIP. Cedric Mullins leads the Baltimore Orioles with 24 hits and 20 RBI, while Jordan Westburg and Ryan O’Hearn have combined for 40 hits and 14 RBI.
Tomoyuki Sugano gets the ball for the Baltimore Orioles, and he is 2-1 with a 3.54 ERA and 9 strikeouts this season. This will be Sugano’s first career game against the New York Yankees.
Why the Baltimore Orioles will win
- The Orioles have won each of their last eight games against AL East opponents following a road loss.
- The Yankees have lost each of their last seven night games against the Orioles following a win.
- The Orioles have covered the run line in each of their last eight night games against AL East opponents following a road loss.
- The Yankees have failed to cover the run line in 12 of their last 13 night games against the Orioles following a win.
Why the New York Yankees will win
- The Yankees have won six of their last seven road games against American League opponents that held a losing record.
- The Orioles have lost each of their last four night games at Oriole Park at Camden Yards following a road loss.
- The Orioles have failed to cover the run line in each of their last four home games against AL East opponents.
- The Yankees have covered the run line in four of their last five games against American League opponents.
- The Yankees have led after 5 innings in five of their last six road games.
- The Yankees have led after 3 innings in five of their last six road games against American League opponents.
Baltimore Orioles Player Prop Facts
- Ryan O'Hearn has hit a home run in three of his last four appearances with the Orioles against AL opponents.
- Gunnar Henderson has recorded a Double in three of the Orioles' last four night games against opponents that held a winning record.
- Gunnar Henderson has scored at least one run in each of the Orioles' last seven Monday night games against AL opponents that held a winning record.
- Ramon Urias has recorded at least one hit in each of his last nine appearances with the Orioles as underdogs against the Yankees.
- Colton Cowser has recorded at least one RBI in four of his last five appearances in night games against AL teams that held a winning record.
- Ryan Mountcastle has recorded a Single in each of the Orioles' last eight games as underdogs against the Yankees.
New York Yankees Player Prop Facts
- Anthony Volpe has recorded a Double in three of the Yankees' last four games against AL East opponents.
- Aaron Judge has hit a home run in five of the Yankees' last six games as favorites against the Orioles.
- Oswaldo Cabrera has scored at least one run in six of his last seven road appearances against AL opponents that held a losing record.
- Paul Goldschmidt has recorded at least one Single in each of the Yankees' last 10 road games against AL opponents.
- Giancarlo Stanton has recorded at least one RBI in each of his last seven road appearances against AL opponents.
- Giancarlo Stanton has recorded at least one hit in each of his last eight appearances with the Yankees as road favorites.
- Aaron Judge ranks 1st amongst qualified players for Batting Average (.406) this season.
New York Yankees vs Baltimore Orioles Prediction
The Yankees and the cheap price are surprising when you consider they’ve comfortably been the better team up to this point. Yes, Warren hasn’t been great through 20.2 innings, allowing 16 hits and 11 runs while walking 10. However, the Orioles are arguably the most disappointing team in baseball through 27 games, and that includes losses in six of their last seven games. The Orioles aren’t scoring runs, and their pitching staff has several games where they get tattooed. Sugano is a 35-year-old rookie who has held his own for the most part, but we’re not getting enough plus money for me to get behind the Orioles. I trust the Yankees' lineup more, and the price is cheap. Give me the Yankees.
Randy’s Pick New York Yankees -122
AUTHOR: Randy Chambers

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