St. Louis Cardinals vs Atlanta Braves Prediction 4/21/25 MLB Picks

Cardinals Swept In Four-Game Set Vs. Mets

Brendan Donovan has a team-high 31 hits along with 7 doubles, 3 home runs, and 13 RBIs, while Lars Nootbaar has 20 hits with 3 home runs, 11 RBIs, and a pair of stolen bases. Nolan Arenado also has 21 hits with 6 doubles of his own, and Victor Scott II has 16 hits with a pair of doubles, a triple, 7 RBIs, and a team-high 7 stolen bases. Ivan Herrera’s also added a team-high 4 home runs and 11 RBIs so far this season.

Why the St. Louis Cardinals will win

• The Braves have lost each of their last seven games as home favorites against NL Central opponents.
• The Cardinals have won three of their last four games as underdogs against the Braves following a loss.
• The Braves have failed to cover the run line in each of their last 11 home games against NL Central opponents.
• The Cardinals have covered the run line in seven of their last eight night games against National League opponents following a road loss.

St. Louis Cardinals Player Prop Facts

• Willson Contreras has hit a home run in each of the Cardinals' last two games against NL East opponents that held a losing record.
• Brendan Donovan has recorded a Double in each of the Cardinals' last three night games against opponents that held a losing record.
• Alec Burleson has recorded at least one RBI in each of the Cardinals' last six games against the Braves.
• Nolan Gorman has scored at least one run in each of his last six appearances at Truist Park.
• Brendan Donovan has recorded at least one Single in each of the Cardinals' last eight road games against opponents that held a losing record.
• Erick Fedde has recorded four or more strikeouts in seven of his last eight appearances against NL East opponents that held a losing record.
• Brendan Donovan has recorded at least one hit in each of the Cardinals' last 13 games against opponents that held a losing record.
• Brendan Donovan ranks 2nd in the league in Hits (31) this season.

Atlanta Braves Recap

The Atlanta Braves come into this game looking to build on their 6-2 win over the Minnesota Twins last time out to improve to 8-13 on the year. After this series, the Braves will head on the road to take on the Arizona Diamondbacks.

Braves Complete Sweep Of Twins

Austin Riley leads the Braves with 23 hits, including 5 home runs, 13 RBIs, and a team-high 4 doubles, but also has the dubious distinction of leading Atlanta with 31 strikeouts so far this season. Ozzie Albies has 20 hits with 4 home runs and 11 RBIs, and Matt Olson has 17 hits with 4 doubles, 3 home runs, and 13 RBIs of his own. Marcell Ozuna also has 18 hits with 4 home runs and 9 RBIs. Michael Harris II also has 16 hits with 3 doubles, 3 home runs, and 9 RBIs, and 4 stolen bases as well, and Nick Allen has a team-high 4 stolen bases this season.

Why the Atlanta Braves will win

• The Cardinals have lost nine of their last 10 road games.
• The home team has won seven of the Cardinals' last eight games.
• The Cardinals have failed to cover the run line each of their last 11 night games against NL East opponents that held a losing record.
• The Braves have covered the run line in three of their last four games at Truist Park.

Atlanta Braves Player Prop Facts

• Michael Harris has hit at least one home run in each of the Braves' last three games against NL Central opponents.
• Ozzie Albies has recorded a Single in each of his last 11 home appearances against NL opponents that held a losing record.
• Ozzie Albies has recorded at least one hit in each of his last 21 home appearances against NL opponents that held a losing record.
• Ronald Acuna Jr. has recorded at least one RBI in eight of his last nine home appearances against NL Central opponents.
• Bryan De La Cruz has scored a run in 10 of his last 11 home appearances against NL Central opponents.
• Marcell Ozuna ranks 2nd amongst qualified players for On Base Percentage (.468) this season.

Total Runs Facts

• Five of the Braves' last six home games after playing the previous day have gone UNDER the total runs line.
• Eight of the Cardinals' last 10 games as underdogs against NL East opponents have gone UNDER the total runs line.

St. Louis Cardinals vs. Atlanta Braves Prediction

I’m on the Braves here. I get the case to be made for the Cardinals if this game were played in St. Louis, but the Cardinals haven’t been able to keep up their play on the road this season, and I think they could struggle here as well. Schwellenbach is still one of Atlanta’s best, and I think he delivers another strong outing here to get the win for the Braves. Give me Atlanta in this one.