Detroit Tigers vs Milwaukee Brewers Prediction 4/16/25 MLB Picks

The projected starting pitcher for the Tigers is Keider Montero, who will get his first start of the season. Last year, Montero had a 6-6 record in 16 starts, with a 4.76 ERA and 1.33 WHIP in 98.1 innings.

Milwaukee Brewers Betting Preview

The Milwaukee Brewers (9-9, 6-3) returned home from a two-series road trip against the Colorado Rockies and Arizona Diamondbacks. Milwaukee beat the Rockies 2-1 and lost to the D-backs 2-1. They were on a three-game losing skid after the Game 1 defeat to the Tigers in the current series. However, for the fourth time this year, the Brewers kept the opponents off the scoreboard in a 5-0 win. Rhys Hoskins led the offense with a homer and two RBI, while Quinn Priester got the win after allowing no runs on one hit with four strikeouts and three walks over 5.0 innings of work.

This year, the Brewers average 4.82 runs per game (9th in the MLB) on a .231/.304/.366 triple-slash. When it comes to pitching, the Brewers’ staff has a 4.99 ERA (28th) and 1.38 WHIP (23rd). Jackson Chourio leads the Brewers with a .275 batting average, five home runs, and 17 RBI this season.

Jose Quintana will take the mound for the Brewers on Wednesday. The 36-year-old left-hander has a 1-0 record in one start this season with a 0.00 ERA and 0.57 WHIP in 7.0 innings.

Total Runs Facts

• Five of the Tigers' last six road games after playing the previous day have gone UNDER the total runs line.
• Four of the Brewers' last five games as favorites against American League opponents have gone UNDER the total runs line.
• The 'Inning 1 UNDER 0.5 runs' market has hit in each of the Tigers' last six games as road underdogs against NL Central opponents.
• The 'Inning 1 OVER 0.5 runs' market has hit in seven of the Brewers' last eight day games at American Family Field.

Matchup/League Facts

• The Brewers rank 28th in the league for runs allowed this season (93).
• The Brewers rank 6th in the league for runs scored this season (87).
• The Tigers rank T27th in the league for strikeouts against this season (167).
• The Tigers rank T4th in the league for hits allowed this season (115).

Tigers vs Brewers Prediction

The Tigers won six of the previous ten H2H encounters, but the Brewers were better in four of the last six. On Tuesday, it was the first time in 12 H2Hs that Detroit failed to score, and I don't think they will fire blanks on Wednesday as well. Jose Quintana had an excellent first start of the season, but this time out, he will surrender some runs early on. The Tigers have a .232 BA with five home runs and 25 RBI against southpaws this season. Quintana allowed a .444 BA in 18 at-bats against the Tigers. Keider Montero didn't play this season, and I expect him to be a bit rusty on Wednesday. Go with Over.