Arizona Diamondbacks vs New York Yankees Prediction 4/1/25 MLB Picks

The projected starting pitcher for the Diamondbacks is Corbin Burnes, who went for a 15-9 record last year in 32 starts with a 2.92 ERA and 1.10 WHIP over 194.1 innings for the Baltimore Orioles.

New York Yankees Betting Preview

The New York Yankees (3-0, 3-0 Home) dominantly opened a new season by sweeping the Milwaukee Brewers in three games. Not only did the Yankees beat the Brewers in all three games, but they simply destroyed them in the last two, scoring 32 runs and 36 in total in the series. A phenomenal start for the team that wants to play in the World Series again after losing last year to the Los Angeles Dodgers.

This year, the Yankees average 12.00 runs per game (1st in the MLB) on a .333/.427/.804 slash line. The Yankees’ pitching staff has a 3.33 ERA (14th) and 1.26 WHIP (17th). Aaron Judge is the best offensive player for the Yankees, with a .545 batting average, four home runs, and 11 RBI this season.

Will Warren will take the mound for the Yankees on Tuesday. The 25-year-old right-hander had a 0-3 record last season in five starts with a 10.32 ERA and 1.90 WHIP in 22.2 innings.

Why the Diamondbacks will beat the Yankees

• The Diamondbacks have won seven of their last eight road games against American League opponents following a win.
• The Yankees have lost five of their last six night games against National League opponents.
• The Diamondbacks have covered the run line each of their last five road games against teams that held a winning record.
• The Yankees have failed to cover the run line in each of their last four night games against National League opponents following a win.
• The Yankees have trailed after 5 innings in three of their last four games as underdogs against National League opponents.

Total Runs Facts

• Thirteen of the Diamondbacks' last 15 night games against American League opponents have gone OVER the total runs line.
• Four of the Yankees' last five home games against NL West opponents have gone OVER the total runs line.
• The 'Inning 1 OVER 0.5 runs' market has hit in each of the Yankees' last seven games at Yankee Stadium.
• The 'Inning 1 OVER 0.5 runs' market has hit in four of the Diamondbacks' last five games as road favorites against AL East opponents.

Diamondbacks vs Yankees Prediction

These teams have traded victories in the past few years, as each recorded five in the previous ten H2H encounters. The Yankees did win five of the last seven, though. The Yanks have problems with injured pitchers, so they are forced to start inexperienced Warren here, which is a great chance for the D-backs to exploit and get a win. Warren struggled in his five starts last year, his first in the majors, and I believe he will struggle again on Tuesday. By the time the bullpen comes in, it's going to be too late for the Yankees. 

Corbin Burnes, on the other hand, is one of the best pitchers in the MLB, and he had a 2.45 ERA in two starts (11.0 innings) against the Yanks last year. He is experienced enough to keep the red-hot Yankees at bay and put them back on earth following a crazy start to the season. I am going with the D-backs.