St. Louis Cardinals vs San Francisco Giants Prediction MLB Picks 9/27/24

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San Francisco Giants (79-80) vs St. Louis Cardinals (81-78)

September 27, 2024 at 10:15 PM EDT

The Line: Betting Odds: San Francisco Giants -118 / St. Louis Cardinals +100 — Over/Under: 7.5

(Get latest betting odds)

In this article, we will formulate a St. Louis Cardinals vs San Francisco Giants Prediction for this MLB game on Friday, September 27th, at Oracle Park. To formulate this prediction, we will examine:

-The Cardinals’ recent form and recent player performance 

-The Giants’ recent form and recent player performance

-Recent Betting trends and streaks involving St Louis

-Recent Betting trends and streaks involving San Francisco

-Recent betting trends in games played between St. Louis and San Francisco

-A summary that ties it all together and produces a favorable betting outcome for Today’s Game between the Cardinals and Giants. 

Cardinals Struggled 

The Cardinals offense scored eight runs on Thursday, but the pitching gave up ten and that led to the defeat. There were four different players that hit a home run. Ryan Fernandez only went an inning and gave up three hits and four earned runs. The Cardinals are averaging 4.09 runs while their pitching is giving up 4.42 runs per game the offense is ranked 23rd in the league while the defense is ranked 18th. Alec Burleson has hit 21 home runs and driven in 74 RBIs so far this season. Getting the start for the Cardinals will be Miles Mikolas who sits with a 9-11 record and an ERA of 5.35. In his last start against the Cleveland Guardians, he went six innings giving up four hits and one run. 

Giants Coming off Series Win

The Giants were able to pick up a series win in the last series against the Arizona Diamondbacks. In the last game though, the pitching gave up eight runs and they ended up losing. The Giants are averaging 4.29 runs while their pitching is giving up 4.29 runs per game. The offense is ranked 17th in the league while the defense is ranked 15th in the league. Matt Chapman has hit 27 home runs and driven in 78 RBIs so far this season. Getting the start for the Giants will be Landen Roupp who sits with a 1-1 record and an ERA of 2.70. Against the Royals, he went five innings giving up three hits and zero runs. 

Why the Giants Will Beat the Cardinals

  • The favorites have won each of the Giants’ last nine games at Oracle Park.
  • The Cardinals have lost four of their last five road games after playing the previous day.
  • The Giants have covered the run line in each of their last six night games against National League opponents following a road loss.

St. Louis Cardinals vs San Francisco Giants Prediction

Mikolas is coming off a strong start but overall he sits with an ERA of 5.35 and he’s going to struggle here. The Giants are going to get a strong start from Roupp who in his last start gave up zero runs and an ERA of 2.70. Look for the Giants to get out to a fast start from Mikolas and that will be the difference here as San Francisco will get the job done. Back the Giants on the money line to cash. 

Shane Mickle's Pick: Giants ML

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