Chicago White Sox vs San Diego Padres Prediction MLB Picks 9/22/24

The Chicago White Sox and the San Diego Padres square off Sunday in MLB action from Petco Park. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Chicago White Sox vs. San Diego Padres prediction.

Starting Pitching Matchup

The Chicago White Sox will trot out Sean Burke for the start here and is 1-0 with a 2.25 ERA and 8 strikeouts this season. This will be Burke’s first career start against the Padres. Yu Darvish will get the nod for the Padres here and is 6-3 with a 3.21 ERA and 65 strikeouts this season. In his last five starts against the White Sox, Darvish is 2-1 with a 2.45 ERA and 34 strikeouts.

Chicago White Sox Recap

The Chicago White Sox come into this one looking to avoid the sweep and salvage something from this series after falling flat in Saturday’s matchup by a final score of 6-2. The series loss for the White Sox makes it back-to-back series defeats after falling short against the Angels earlier in the week.

White Sox Trying To Avoid Wrong Kind Of History In This Game

Gavin Sheets has a .236 batting average and a .308 OBP along with 24 doubles and 45 RBIs while Andrew Vaughn has 19 homers and 67 RBIs and Andrew Benintendi has 19 home runs and 60 RBIs with Vaughn logging 30 doubles as well as a team-high 133 hits.

Why the Chicago White Sox will win

• The Padres have lost each of their last six-day games against AL Central opponents following a home win.
• The White Sox have won each of their last three-day games against NL West opponents following a road loss.
• The Padres have failed to cover the run line each of their last 12-day games against AL Central opponents that held a losing record.
• The White Sox have covered the run line in six of their last seven-day games against NL West opponents following a loss.

San Diego Padres Recap

The San Diego Padres will look to complete the sweep after picking up another victory in Saturday’s win. The series win for the Padres added to their series win streak which includes sets over the Astros and Giants over the last week and a half.

Padres Trying To Clinch Wild Card

Jurickson Profar has 153 hits along with a .283 batting average and 28 doubles with 23 homers and 83 RBIs. Jake Cronenworth has 78 RBIs while Fernando Tatis Jr. has belted 19 home runs, 47 RBIs, and 106 hits as well this season. Manny Machado has 158 hits, 29 home runs, and 104 RBIs but also has 119 strikeouts while Ha-Seong Kim has 94 hits with 3 triples, 16 doubles, 11 home runs, 47 RBIs, and a team-high 22 stolen bases. Jackson Merrill has also chipped in 24 home runs, 89 RBIs, and 29 doubles with 6 triples this season.

Why the San Diego Padres will win

• The White Sox have lost 14 of their last 15 games against National League opponents.
• The Padres have won seven of their last eight games.
• The White Sox have failed to cover the run line in 11 of their last 12 games against National League opponents after playing the previous day.
• The Padres have covered the run line in four of their last five-day games against AL Central opponents.

White Sox vs. Padres Prediction

I’m on the Padres in this one. The bottom line is that the White Sox just can’t score. A loss here would tie the White Sox up for the most losses in a season with 120 and I have a feeling they’re going to make the wrong kind of history later this week. The Padres are so close to a Wild Card spot and Darvish has started to lock in after getting comfortable again since returning from the IL. Give me the Padres in this one.