Baltimore Orioles vs Houston Astros Prediction MLB Picks 6/21/24

Pick details

Houston Astros (35-40) vs Baltimore Orioles (49-25)

June 21, 2024 at 08:10 PM EDT

The Line: Betting Odds: Houston Astros +135 / Baltimore Orioles -155 — Over/Under: 8.5

(Get latest betting odds)

In this article we will formulate a Baltimore Orioles vs Houston Astros prediction for this MLB game on Friday, June 21st at Minute Maid Park in Houston, Texas. To formulate this prediction for game one in the series, we will examine:

  • The Orioles recent form and recent player performance 
  • The Astros recent form and recent play performance
  • Recent Betting trends and streaks involving Baltimore
  • Recent Betting trends and streaks involving Houston
  • Recent betting trends in games played between Baltimore and Houston
  • A summary that ties it all together and produces a favorable betting outcome for Today’s Game between Baltimore and Houston

Orioles Coming Off of a Blowout Win 

The Baltimore Orioles are 49-25 this season and they have won four of their last five games. Baltimore is coming off of a series win against New York, where they won two out of three games and scored 17 runs on Thursday. Prior to that series, the Orioles won two out of three against the Phillies, won two out of three against the Braves, and swept the Rays in four games. Baltimore is 10-3 in their last 13 games and they are second in the AL East.

The Baltimore pitching staff has a 3.13 ERA, a 1.14 WHIP, and a .217 opponent batting average. The Orioles offense has scored 390 runs with a .252 batting average and a .313 on base percentage. Gunnar Henderson is batting .279 with 22 home runs and 50 RBI’s for Orioles this season. Baltimore has scored at least six runs in four of their last five games. 

Astros are Playing Better 

The Houston Astros are 35-40 this year and they have won three of their last four games. Houston is coming off of a series win against the White Sox, where they won two out of three games. Prior to that series, the Astros won two out of three against the Tigers, lost two out of three against the Giants, and won two out of three against the Angels. Houston is 5-3 in their last eight games and they are second in the AL West. 

The Houston pitching staff has a 4.12 ERA, a 1.31 WHIP, and a .238 opponent batting average. The Astros offense has scored 328 runs with a .259 batting average and a .319 on base percentage. Yordan Alvarez is batting .296 with 15 home runs and 39 RBI’s for the Astros this season. Houston has scored at least four runs in five of their last six games. 

Starting Pitchers

The projected starting pitcher for Baltimore is Grayson Rodriguez, who is 8-2 with a 3.20 ERA and a 1.22 WHIP over 70.1 innings pitched this season. Rodriguez has allowed two earned runs or fewer in four of his last five starts. The projected starting pitcher for Houston is Jake Bloss, who is making his first MLB start. Bloss has made eight starts in Double-A and will skip over the Triple-A level. 

Why the Baltimore Orioles will win

  • The Orioles have won each of their last 10 games as road favorites against American League opponents.
  • The Astros have lost seven of their last eight home games against AL East opponents that held a winning record.
  • The Orioles have covered the run line in each of their last 14 road games against American League opponents after playing the previous day.
  • The Astros have failed to cover the run line in seven of their last eight games at Minute Maid Park following a win.
  • The Astros have trailed after 5 innings in each of their last five Friday night games against American League opponents that held a winning record.

Total Runs Facts

  • Sixteen of the Astros’ last 18 games against American League opponents have gone UNDER the total runs line.
  • Each of the Orioles’ last three games after playing the previous day have gone OVER the total runs line.
  • The ‘Inning 1 UNDER 0.5 runs’ market has hit in each of the Astros’ last six night games.
  • The ‘Inning 1 OVER 0.5 runs’ market has hit in each of the Orioles’ last three games at Minute Maid Park.

Houston Astros Player Prop Facts

  • Alex Bregman has hit a home run in three of the Astros’ last four games against opponents that held a winning record.
  • Kyle Tucker has recorded at least one RBI in six of the Astros’ last eight games against the Orioles.
  • Alex Bregman has recorded at least one Single in seven of the Astros’ last eight night games.
  • Jose Altuve has recorded a hit in each of the Astros’ last nine night games against opponents that held a winning record.
  • Jose Altuve has recorded at least one total base in each of the Astros’ last nine night games against opponents that held a winning record.
  • Jose Altuve has scored at least one run in each of the Astros’ last four home games against AL East opponents.

Baltimore Orioles Player Prop Facts

  • Gunnar Henderson has recorded at least one hit in each of his last 13 appearances.
  • Adley Rutschman has recorded at least one total base in each of his last 13 appearances in night games against AL teams that held a losing record.
  • Gunnar Henderson has scored at least one run in each of the Orioles’ last seven games against AL opponents.
  • Gunnar Henderson has hit a home run in four of the Orioles’ last five games as favorites against AL West opponents.
  • Anthony Santander has recorded at least one RBI in five of the Orioles’ last six games.
  • Gunnar Henderson has recorded at least one Double in four of the Orioles’ last five road games against AL opponents.
  • Adley Rutschman has recorded at least one Single in 16 of his last 17 appearances with the Orioles as road favorites against AL opponents.

Baltimore Orioles vs Houston Astros Prediction 

Both of these teams come into this series playing well, but the Orioles have been one of the best teams in the MLB this season. Baltimore is 24-11 on the road and just took two out of three against the Yankees on the road. Houston is 19-19 at home and they are starting Jake Bloss, who I think is going to struggle here. The Astros are dealing with a lot of injuries to their rotation, so they are forced to bring Bloss up, which isn’t ideal against Baltimore. My Baltimore Orioles vs Houston Astros prediction is for the Orioles to win by at least two runs. 

David Racey's Pick: Orioles -1.5

Need More? Get Premium Picks

Hot Cappers

Latest Picks & Game Previews

  • Weber State vs Arizona Prediction 9/6/2025 Today’s College Football Picks

    September 06, 2025

  • San Diego State vs Washington State Prediction 9/6/2025 Today’s College Football Picks

    September 06, 2025

  • Stanford vs BYU Prediction 9/6/2025 Today’s College Football Picks

    September 06, 2025

  • UC Davis vs Washington Prediction 9/6/2025 Today’s College Football Picks

    September 06, 2025

  • Sam Houston State vs Hawai’i Prediction 9/6/2025 Today’s College Football Picks

    September 06, 2025

  • Pittsburgh Steelers vs New York Jets Prediction 9/7/2025 Today’s NFL Picks

    September 07, 2025

  • Arizona Cardinals vs New Orleans Saints Prediction 9/7/2025 Today’s NFL Picks

    September 07, 2025

  • Carolina Panthers vs Jacksonville Jaguars Prediction 9/7/2025 Today’s NFL Picks

    September 07, 2025

  • Tampa Bay Buccaneers vs Atlanta Falcons Prediction 9/7/2025 Today’s NFL Picks

    September 07, 2025

  • Las Vegas Raiders vs New England Patriots Prediction 9/7/2025 Today’s NFL Picks

    September 07, 2025