Manchester City Manchester City vs Arsenal FC Arsenal FC Prediction 9/21/2025 Today’s EPL Picks

In this article, we will formulate a Manchester City vs Arsenal Prediction for this English Premier League Week 5 matchup on Sunday, September 21st, at the Stadium of Light. Let’s take a look at the prediction for this English Premier League matchup.

Arsenal Preview

Arsenal has 9 points this season, with a 3-1-0 record, and are sitting on the 2nd place in the Premier League standings. They have a 2-0-0 home record and a 1-1-0 away record. Arsenal is coming off a 3-0 home win against Nottingham Forest, where they had 54% possession of the ball and 16 total shots, 5 of them on target. They had 87% completed passes, and more expected goals, with 1.84 compared to Nottingham Forest’s 0.20.

Arsenal is scoring 2.25 goals per game, which ranks 2nd in the Premier League, while allowing 0.25 goals per game, which is 2nd. Viktor Gyökeres is Arsenal’s top scorer with 3 goals, followed by Martín Zubimendi and Jurriën Timber with 2 goals each, and Bukayo Saka and Riccardo Calafiori with 1 goal apiece. Riccardo Calafiori is Arsenal’s top passer, with 2 assists.

Manchester City Preview

Manchester City has 6 points this season, with a 2-2-0 record, and are sitting on the 8th place in the Premier League standings. They have a 1-1-0 home record and a 1-1-0 away record. Manchester City is coming off a 3-0 home win against Manchester United, where they had 45% possession of the ball and 13 total shots, 6 of them on target. They had 82% completed passes, and more expected goals, with 2.63 compared to Manchester United’s 1.52.

Manchester City is scoring 2.00 goals per game, which ranks 8th in the Premier League, while allowing 1.00 goals per game, which is 8th. Erling Haaland is Manchester City’s top scorer with 5 goals, followed by Tijani Reijnders, Ryan Cherki and Phil Foden with 1 goal apiece. Jeremy Doku is Manchester City’s top passer, with 2 assists.

Why Arsenal will win

·        The favorite has won each of Arsenal’s last six EPL matches.

·        The favorite has won seven of Manchester City’s last eight EPL matches at Emirates Stadium.

·        The home team has won each of Arsenal’s last three EPL matches.

·        Arsenal has won each of its last five EPL matches as a favorite.

·        Arsenal has won five of its last six EPL matches.

·        Arsenal has won 16 of its last 20 EPL Sunday home matches.

·        Manchester City has lost seven of its last eight EPL Sunday matches as an underdog.

Why Manchester City will win

·        Manchester City has won five of its last six EPL matches at Emirates Stadium following a league win.

·        Manchester City has won 12 of its last 16 EPL matches against Arsenal.

·        Manchester City has won six of its last eight EPL away matches against Arsenal.

Total Points Facts

·        Manchester City has won six of its last eight EPL away matches against Arsenal.

·        The ‘Over 2.5 Goals’ market has hit in 15 of the last 20 EPL matches between Arsenal and Manchester City.

·        The ‘Over 3.5 Goals’ market has hit in four of the last six EPL matches between Arsenal and Manchester City.

·        The ‘Over 2.5 Goals’ market has hit in four of Arsenal’s last five EPL home matches.

Manchester City vs Arsenal Prediction

In their two meetings last season, Arsenal beat Manchester City 5-1 at home, while both teams had a 2-2 draw at Etihad Stadium. Arsenal is 3-1-1 in their last 5 meetings against Manchester City. Both teams to score – Yes is 5-3 in their last 8 meetings, and over 2.5 goals is 5-3 in their last 8 meetings.

In this Manchester City vs Arsenal Prediction, Arsenal is coming as +110 road favorites. Arsenal has been great this season, having won three of their four games, but both teams have back-to-back wins, including mid-week victories for the Champions League. Both teams have been very efficient offensively so far, scoring 4.25 goals per game combined, and their two meetings last season had 6 and 4 total goals. I expect another high-scoring affair today, so take the over 2.5 goals in this one.