Wyoming vs North Dakota State Prediction 10/3/2026 Today’s College Football Picks

In this article we will formulate a Wyoming vs North Dakota State prediction for this College Football game on Saturday, October 3rd at the Fargodome in Fargo, North Dakota. Let’s take a look at the prediction for this Week 5 matchup. 

Wyoming Cowboys Betting Preview

The Wyoming Cowboys are 2-2 (1-0) this season after they defeated Hawaii by a score of 27-10 last week. Wyoming led 13-3 at halftime and they won the second half 14-7 to seal the victory. The Cowboys out gained Hawaii by a total of 387-328, went 6-12 on third downs, and tied the turnover battle at zero in the game. Tyler Hughes threw for 204 yards, while Deion DeBlanc caught three passes for 41 yards. Samuel Harris rushed 11 times for 94 yards and one score in the win. 

Prior to that game, Wyoming lost to Central Michigan by a score of 24-10, but did beat Northern Colorado by a score of 21-13 before that. The Cowboys have scored 17.8 points per game with 165.8 passing yards and 160.3 rushing yards per game, while they have allowed 20.5 points against per game this season. Tyler Hughes has thrown for 656 yards with two touchdowns and five interceptions, while Samuel Harris has rushed 42 times for 226 yards and two scores this season. 

North Dakota State Bison Betting Preview

The North Dakota State Bison are 4-0 (1-0) this year after they defeated Sacramento State by a score of 31-10 in their last game. North Dakota State led 28-3 at halftime, but they were outscored 7-3 in the second half in the victory. The Bison out gained their opponent by a total of 362-328, went 6-12 on third downs, and won the turnover battle by a total of 3-0 in the game. Nathan Hayes threw for 210 yards and one touchdown, while Jackson Williams caught seven passes for 134 yards and one score. DJ Scott rushed 14 times for 80 yards and one touchdown in the win. 

Prior to that game, North Dakota State defeated Air Force by a score of 38-32 and Fordham by a score of 38-0. The Bison have scored 35.0 points per game with 211.8 passing yards and 158.8 rushing yards per game, while they have allowed 12.3 points against per game this season. Nathan Hayes has thrown for 808 yards with seven touchdowns and two interceptions, while DJ Scott has 225 rushing yards and three scores on 50 carries this year. 

Why the North Dakota State Bison will win

• Wyoming has lost each of its last seven road games against non-AP-ranked teams.
• The home team has won each of Wyoming’s last five games.
• Wyoming has failed to cover the spread in seven of its last eight games against non-AP-ranked teams.
• The favorite has won the first half in each of North Dakota State’s last four games.

Why the Wyoming Cowboys will win

• Wyoming has covered the spread in five of its last six October games against non-AP-ranked teams.

Total Points Facts

• Ten of Wyoming’s last 11 games against conference opponents have gone UNDER the total points line.
• Three of North Dakota State’s last four games as a favorite have gone UNDER the total points line.

North Dakota State Bison Player Prop Facts

• Heading into Week 5, Nathan Hayes ranks 1st in the Mountain West Conference amongst qualified players for passer rating (162.6) this season.

Wyoming Cowboys Player Prop Facts

• Heading into Week 5, Kyle Frendt ranks 1st in the Mountain West Conference amongst qualified players for catch rate (100.0%) this season.

Matchup/League Facts

• North Dakota State ranks T3rd among FBS teams for interceptions this season (7).
• North Dakota State ranks T7th among FBS teams for average point differential in third quarters this season (+9.5).
• Wyoming ranks T132nd among FBS teams for Q1 points per game this season (1.5).
• Wyoming ranks T125th among FBS teams for Q3 points per game this season (2.5).

Wyoming vs North Dakota State Prediction 

North Dakota State comes into this matchup undefeated so far and they have won by at least 21 points in three of their four games. The Bison have allowed 10 or fewer in three of their four games and they are excellent at home. Wyoming is 0-2 on the road and they have scored a total of 23 points in those two losses. The Cowboys are a different team on the road and we can’t trust them to score, so give me NDSU to cover again here.

David Racey's Pick: North Dakota State -17.5