Louisiana vs Charlotte Prediction 9/26/2026 Today’s College Football Picks

In this article we will formulate a Louisiana vs Charlotte prediction for this College Football game on Saturday, September 26th at Jerry Richardson Stadium in Charlotte, North Carolina. Let’s take a look at the prediction for this Week 4 matchup. 

Louisiana Ragin’ Cajuns Betting Preview

The Louisiana Ragin’ Cajuns are 2-1 this year after they defeated UAB by a score of 21-14 last week. Louisiana led 21-7 at halftime and they were able to get the win, but they failed to score in the second half. The Ragin’ Cajuns out gained UAB by a total of 335-218, went 6-16 on third downs, and lost the turnover battle by a total of 2-1 in the game. Lunch Winfield threw for 110 yards, while Landon Strother caught five passes for 41 yards. Winfield also led the rushing attack with 91 yards and two scores on 19 carries in the game. 

Prior to that win, Louisiana lost to USC by a score of 49-30, but did defeat Lamar by a score of 38-7 before that. The Ragin’ Cajuns have scored 29.7 points per game with 184.3 passing yards and 204.7 rushing yards per game, while they have allowed 23.3 points against per game this season. Lunch Winfield has thrown for 511 yards with one touchdown and two interceptions, while also rushing for 267 yards and five scores this year. 

Charlotte 49ers Betting Preview

The Charlotte 49ers are 0-3 this season after they lost to App State by a score of 26-21 in their last game. Charlotte trailed 13-7 at halftime and they allowed the first 13 points of the second half, before falling short in their comeback attempt. The 49ers were out gained by a total of 435-247, went 1-10 on third downs, and tied the turnover battle at two in the game. Cole Gonzales threw for 211 yards and two interceptions, while Jaden Barnes caught 10 passes for 97 yards. Henry Rutledge rushed seven times for 29 yards in the loss. 

Prior to that game, Charlotte lost to Ole Miss by a score of 41-9 and The Citadel by a score of 43-41. The 49ers have scored 23.7 points per game with 237.3 passing yards and 131.7 rushing yards per game, while they have allowed 36.7 points against per game this season. Cole Gonzales has thrown for 661 yards with three touchdowns and five interceptions, while Jaden Barnes has 21 receptions for 207 yards this season. 

Why the Charlotte 49ers will win

• Louisiana has lost four of its last five September games as a road favorite against non-AP-ranked teams.
• Charlotte has covered the spread in each of its last four games as an underdog.
• Louisiana has failed to cover the spread in six of its last seven September games as a road favorite.

Why the Louisiana Ragin’ Cajuns will win

• Charlotte has lost each of its last nine games against non-AP-ranked teams.
• The favorite has won 14 of Charlotte’s last 15 games.
• The road team has covered the spread in 11 of Charlotte’s last 12 games.
• Charlotte has failed to cover the spread in eight of its last nine home games in September.
• The favorite has won the first half in 11 of Charlotte’s last 12 games.

Total Points Facts

• Each of Louisiana’s last four road games in September have gone OVER the total points line.
• Five of Charlotte’s last six games have gone UNDER the total points line.

Charlotte 49ers Player Prop Facts

• Heading into Week 4, Jason Jeffares ranks T1st in the American Conference amongst qualified players for catch rate (100.0%) this season.

Louisiana Ragin’ Cajuns Player Prop Facts

• Heading into Week 4, D’Wayne Winfield ranks T7th amongst FBS players for rushing touchdowns (5) this season.

Matchup/League Facts

• Charlotte ranks 123rd among FBS teams for passing yards allowed per game this season (256.7).
• Charlotte ranks T123rd among FBS teams for average point differential in second quarters this season (-5.3).
• Louisiana ranks T5th among FBS teams for interceptions this season (5).
• Louisiana ranks T10th among FBS teams for 4th down conversion percentage against this season (14.3).

Louisiana vs Charlotte Prediction 

Charlotte comes into this matchup looking for their first win of the season and they already have a terrible loss to a FCS school in week one. The 49ers have allowed 41+ points in two of their three games, but they did play a little better last week. Louisiana is 2-1 so far, but their offense disappeared in the second half last week. The Ragin’ Cajuns don’t have a great passing game, but their QB is great at running. I don’t think we will see many points in this game, but Louisiana should be able to cover here.

David Racey's Pick: Louisiana -10