Iowa State vs Arizona Prediction 10/24/2026 Today’s College Football Picks

The Iowa State Cyclones and Arizona Wildcats meet Saturday in week 8 college football action at Casino Del Sol Stadium. Here’s an Iowa State vs. Arizona Prediction. This article will include an Iowa State vs. Arizona Pick.

Iowa State Cyclones Betting Preview

The Iowa State Cyclones lost to BYU, beat West Virginia, and they play Oklahoma State next. Iowa State has won 6 of its last 9 games. Jaylen Raynor is completing 57.4 percent of his passes for 1,001 yards, 7 touchdowns, and 4 interceptions. Dominic Overby and Omari Hayes have combined for 420 receiving yards and 2 touchdowns, while Cody Jackson has 10 receptions.

The Iowa State Cyclones’ ground game is averaging 181.5 yards per contest, and Aiden Flora leads the way with 680 yards and 6 touchdowns. Defensively, Iowa State is allowing 21.7 points and 352.3 yards per game. Sullivan Schlimgen leads the Iowa State Cyclones with 56 tackles, Isaac Terell has 3 sacks, and Beni Ngoyi has 1 interception.

Arizona Wildcats Betting Preview

The Arizona Wildcats beat Cincinnati and West Virginia, and play Texas Tech next. The Arizona Wildcats have won 4 straight games. Noah Fifita is completing 73.3 percent of his passes for 1,756 yards, 16 touchdowns, and 4 interceptions. Isaiah Mizell and Tre Spivey have combined for 673 receiving yards and 8 touchdowns, while Brandon Phelps has 12 receptions.

The Arizona Wildcats’ ground game is averaging 149.8 yards per contest, and Kedrick Reescano leads the way with 262 yards and 4 touchdowns. Defensively, Arizona is allowing 19 points and 330.5 yards per game. Taye Brown leads the Arizona Wildcats with 39 tackles, Chase Kennedy has 4 sacks, and Quinn Olson has 1 interception.

Why the Arizona Wildcats will win

• Arizona has won each of its last 10 games against non-AP-ranked teams at Casino Del Sol Stadium.
• Iowa State has lost each of its last four October games against AP-ranked teams.
• Iowa State has failed to cover the spread in each of its last four games against conference opponents.
• The favorite has covered the spread in three of Iowa State’s last four games.
• The favorite has won the first half in each of Iowa State’s last four games.

Why the Iowa State Cyclones will win

• Arizona has failed to cover the spread in six of its last seven home games as an AP-ranked team against a non-AP-ranked team.
• Iowa State has covered the spread in 15 of its last 20 October games as an underdog.
• Iowa State has won the first half in three of its last four games in October.

Total Points Facts

• Nine of Arizona’s last 10 games against non-AP-ranked teams at Casino Del Sol Stadium have gone UNDER the total points line.
• Each of Iowa State’s last five road games has gone UNDER the total points line.

Arizona Wildcats Player Prop Facts

• Heading into Week 8, Noah Fifita ranks T10th amongst FBS players for passing touchdowns (16) this season.

Iowa State Cyclones Player Prop Facts

• Heading into Week 8, Aiden Flora leads Iowa State for touchdowns (6) this season.

Matchup/League Facts

• Arizona ranks 10th among FBS teams for passing yards per game this season (306.7).
• Arizona ranks T10th among FBS teams for average point differential in third quarters this season (+5.8).
• Iowa State ranks 127th among FBS teams for 3rd down conversion percentage this season (31.0).
• Iowa State ranks 118th among FBS teams for passing yards per game this season (178.2).

Iowa State vs Arizona Prediction

I like getting points with a team that’s had an extra week to prepare, but Iowa State can’t score the football and has been held to 17 or fewer points in 3 of its last 5 games. That’s not going to fly against a team like Arizona, who is also playing its best ball of the season right now. Arizona just went into Morgantown and dropped 52 points on West Virginia’s head. Iowa State has usually been a sneaky good team as an underdog over the years, but this feels like a bad matchup for the Cyclones, and there aren’t enough horses to keep up. I’ll lay the points with Arizona.

Randy Chambers's Pick: Arizona -10