Charlotte vs Appalachian State Prediction 9/19/2026 Today’s College Football Picks

In this article we will formulate a Charlotte vs Appalachian State prediction for this College Football game on Saturday, September 19th at Kidd Brewer Stadium in Boone, North Carolina. Let’s take a look at the prediction for this Week 3 matchup. 

Charlotte 49ers Betting Preview

The Charlotte 49ers are 0-2 this season after they lost to Ole Miss by a score of 41-9 last week. Charlotte trailed 27-0 at halftime, but was only outscored 14-9 in the second half in the loss. The 49ers were out gained by a total of 420-322, went 3-14 on third downs, and tied the turnover battle at one in the game. Cole Gonzales threw for 128 yards and one interception, while Derrick Eley caught two passes for 56 yards. Chance Williams rushed nine times for 74 yards in the loss. 

Prior to that game, Charlotte lost to the The Citadel by a score of 43-41 in overtime. The 49ers have scored 25.0 points per game with 250.5 passing yards and 179.5 rushing yards per game, while they have allowed 42.0 points against per game this season. Cole Gonzales has thrown for 450 yards with three touchdowns and three interceptions this season. 

Appalachian State Mountaineers Betting Preview

The Appalachian State Mountaineers are 2-0 this year after they defeated East Carolina by a score of 27-24 last week. Appalachian State led 17-10 at halftime, but they were outscored 14-10 in the second half in the narrow win. The Mountaineers were out gained by a total of 417-396, went 5-14 on third downs, and won the turnover battle by a total of 2-0 in the game. Malachi Singleton threw for 267 yards, while Sam Pickett caught four passes for 86 yards. Jaquari Lewis rushed 17 times for 73 yards and one score in the win. 

Prior to that game, Appalachian State defeated Maine by a score of 55-3 in week one. The Mountaineers have scored 41.0 points per game with 307.5 passing yards and 213.5 rushing yards per game, while they have allowed 13.5 points against per game on defense this season. Malachi Singleton has thrown for 558 yards, three touchdowns, and zero interceptions, while Sam Pickett has nine receptions for 162 yards and two scores. Jaquari Lewis has 28 carries for 142 yards and two touchdowns this year. 

Why the Appalachian State Mountaineers will win

• Charlotte has lost 20 of its last 21 road games against non-conference opponents.
• Appalachian State has won 15 of its last 16 games against non-conference opponents at Kidd Brewer Stadium.
• Charlotte has failed to cover the spread in five of its last six games in North Carolina.
• Appalachian State has covered the spread in each of its last three games against non-conference opponents.
• The favorite has won the first half in 10 of Charlotte’s last 11 games.

Why the Charlotte 49ers will win

• Appalachian State has lost three of its last four games as a home favorite.
• The road team has covered the spread in 10 of Charlotte’s last 11 games.
• Appalachian State has failed to cover the spread in 10 of its last 12 September games as a favorite.

Total Points Facts

• Each of Appalachian State’s last four games as a home favorite against teams from North Carolina have gone OVER the total points line.
• Six of Charlotte’s last seven games in North Carolina have gone OVER the total points line.

Appalachian State Mountaineers Player Prop Facts

• Heading into Week 3, Caleb Sandstrom ranks T1st in the Sun Belt Conference for sacks (3.0) this season.

Charlotte 49ers Player Prop Facts

• Heading into Week 3, Cole Gonzales ranks T6th amongst qualified players for sack percentage (1.6%) this season.

Matchup/League Facts

• Appalachian State ranks T8th among FBS teams for average point differential in second quarters this season (+17.5).
• Appalachian State ranks T9th among FBS teams for Q2 points per game this season (19.0).
• Charlotte ranks 124th among FBS teams for average point differential in second quarters this season (-6.5).
• Charlotte ranks T123rd among FBS teams for H2 opponent points per game this season (17.5).

Charlotte vs Appalachian State Prediction 

Charlotte comes into this matchup looking for their first win of the season, but they have allowed 84 points in their first two games. The 49ers lost to a FCS team in week one and never had a chance against Ole Miss in week two. App State is 2-0 on the season and they just picked up a nice win against East Carolina. The Mountaineers have allowed just 27 total points through two games and they should lock down defensively here. I don’t have any faith in this Charlotte team right now, so I will back Appalachian State at home.

David Racey's Pick: App State -17.5