Virginia Tech vs Syracuse Prediction 1/21/2026 Today’s College Basketball Picks

In this article, we will formulate a Virginia Tech vs Syracuse Prediction for this College Basketball game on Wednesday, January 21st. Let’s take a look at the prediction for this College Basketball matchup.

Syracuse Orange Preview

Syracuse Orange have a 12-6 record this season and are tied in the 6th place of the ACC. They have a 3-2 conference record and are coming off an 81-73 overtime away loss against Boston College. Their previous three games were a 94-86 home win against Florida State, an 83-72 away win against Pittsburgh and an 82-72 away win against Georgia Tech.

Offensively, Syracuse averages 75.7 points per game, while allowing 67.7 points per game defensively. The Orange shoot with 47% from the field and grab 36.1 rebounds per game, while dishing out 13.4 assists per game. They average 6.6 blocks per game and 6.6 steals per game defensively.

J.J. Starling leads Syracuse in scoring, with an average of 11.4 points per game, while shooting with 44.8% from the field and 47.6% from the free throw line. William Kyle III is the team’s leading rebounder with 7.6 per game. Naithan George leads the team in assists with 5.6 per game.

Virginia Tech Hokies Preview

Virginia Tech Hokies have a 14-5 record this season and are tied in the 7th place of the ACC. They have a 3-3 conference record and are coming off an 89-76 home win against Notre Dame. Their previous three games were a 77-76 away loss against SMU, a 78-75 home win against California and a 69-68 home loss against Stanford.

Offensively, Virginia Tech averages 82.3 points per game, while allowing 74.1 points per game defensively. The Hokies shoot with 46% from the field and grab 36.6 rebounds per game, while dishing out 14.7 assists per game. They average 3.6 blocks per game and 7.1 steals per game defensively.

Amani Hansberry leads Virginia Tech in scoring, with an average of 15.8 points per game, while shooting with 50% from the field and 70.9% from the free throw line. Hansberry is also the team’s leading rebounder with 8.9 per game. Neoklis Avdalas leads the team in assists with 5.2 per game.

Virginia Tech Hokies @ Syracuse Orange Betting Trends: January 21, 2026

Why the Syracuse Orange will win

• Syracuse has won each of its last nine night games at JMA Wireless Dome.
• Virginia Tech has lost seven of its last eight night games against Conference opponents.
• Syracuse has won the first half in each of its last nine night games at JMA Wireless Dome.

Why the Virginia Tech Hokies will win

• Syracuse has lost each of its last eight games after coming off overtime.
• Virginia Tech has won the first half in six of its last seven night games.

Total Points Facts

• Seven of Virginia Tech’s last eight road night games against Conference opponents have produced a total of 149 or fewer points.
• Each of Syracuse’s last four games have produced a total of 154+ points.

Virginia Tech vs Syracuse Prediction

In this Virginia Tech vs Syracuse Prediction, Syracuse is coming as -2.5 home favorites. Virginia Tech has been slightly better this season but they are just 2-3 in their last 5 games and 2-2 against the spread, while Syracuse has been very strong at their home court and is 6-2 in its last 8 games and 3-1 against the spread. They also have a superior defense, allowing 6.4 points per game less than Virginia Tech and ranking 33rd in the nation in points allowed, so I like them at home in this matchup. Take Syracuse and lay the -2.5 points in this one.

Nikos Lagouretos's Pick: Syracuse -2.5