Vanderbilt vs Missouri Prediction 2/18/2026 Today’s College Basketball Picks

The Vanderbilt Commodores and the Missouri Tigers meet Wednesday in college basketball action from Mizzou Arena in Columbia. Here’s a Vanderbilt vs Missouri prediction. We will look at this from a betting perspective and determine the best Vanderbilt vs Missouri pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Vanderbilt Commodores Betting Preview

The Commodores opened up the season on a great stretch, hitting an unbeaten run 16-0 right out of the gate. Vanderbilt would then lose to Texas, Florida and Arkansas before beating Mississippi State, Kentucky and Ole Miss. After another loss to Oklahoma, the Commodores beat Auburn and Texas A&M in the next pair, giving the team a 21-4 record in the books so far.

In the Texas A&M game over the weekend, the Commodores entered the second half sporting a 36-32 advantage on the scoreboard. Vanderbilt added a 46-37 run the rest of the way, eventually taking the victory 82-69 in a home matchup. The Commodores were led by Tyler Nickel with 25 points and three rebounds in the victory, while AK Okereke had 23 points with five rebounds and three assists. Devin McGlockton added 17 points and eight boards.

Missouri Tigers Betting Preview

Over on the Missouri side, they mustered a pretty solid 12-3 record over their first 15 games this year. The Tigers would hit a 2-4 stretch over the next six games though, losing to Ole Miss, LSU, Georgia and Alabama. After wins over Mississippi State, South Carolina and Texas A&M from there, the Tigers took another loss to Texas. That makes for a 17-8 record in 25 games this season.

Matched up against Texas on Saturday the Tigers were sitting in the locker room with a two-point deficit 33-31. Missouri didn’t end up getting any closer than that on a 52-37 disadvantage the rest of the way, eventually losing on their home court 85-68 by game’s end. Jayden Stone had 16 points with five boards while Mark Mitchell added 16 points with four rebounds.

Vanderbilt Commodores @ Missouri Tigers Betting Trends: February 18, 2026

Why the Missouri Tigers will win

• Missouri has won 31 of its last 35 games at Mizzou Arena.
• Vanderbilt has lost the first half in three of its last four games at Mizzou Arena.

Why the Vanderbilt Commodores will win

• Vanderbilt has won nine of its last 10 night games against non-AP-ranked opponents.
• Missouri has lost four of its last five night games against AP-ranked opponents.
• Missouri has lost the first half in each of its last four night games against Conference opponents.

Vanderbilt vs Missouri Prediction

I’ll stick with Vanderbilt. The Commodores didn’t have too much trouble with Texas A&M over the weekend, shooting 43.9 percent from the field with 79.3 percent (23-of-29) from the line and just eight turnovers. Vanderbilt gave up just 38.9 percent shooting on the other side but also got outscored in the paint 40-28. The Commodores are a nice 5-1 in their last six games, with a lone one-point loss to Oklahoma serving as the blemish.

As for Missouri, they couldn’t keep pace with a good Texas team last weekend. The Tigers shot 42.2 percent from the field with a 34-20 deficit on the boards and a 40-28 disadvantage in the paint while giving up 47.5 percent shooting on defense. Missouri is still 3-1 in their last four games though, scoring 78 or more points in all three of those victories.

Andrew Jett's Pick: Vanderbilt Commodores -4.5