Texas Tech's JT Toppin looks to score against Sam Houston during a nonconference men's basketball game, Friday, Nov. 7, 2025, at United Supermarkets Arena.
Nathan Giese/Avalanche-Journal / USA TODAY NETWORK via Imagn Images

Texas Tech vs Purdue Prediction 11/21/2025 Today’s College Basketball Picks

Pick details

MATCHUP Texas Tech Red Raiders Purdue Boilermakers
Team Records 4-1 5-0
Spread +3.5 -118 -3.5 -102
Moneyline +140 -166
Total Over 154.5 (-108) Under 154.5 (-112)
When Friday, November 21, 2025
Time 09:30 PM EST
TV CBSSN

The Purdue Boilermakers and the Texas Tech Red Raiders meet Friday in college basketball action from the Baha Mar Convention Center. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Purdue Boilermakers vs. Texas Tech Red Raiders prediction.

Purdue Boilermakers Recap

The Purdue Boilermakers come into this game looking to add on to their 80-71 win over Memphis last time out to improve to 5-0 on the year. 

Boilermakers Looking To Remain Unbeaten

Going into Thursday’s game against Memphis, Trey Kaufman-Renn has 18 PPG and 15 RPG aong with 3 APG while Braden Smith has 17.8 PPG with 4.8 RPG and a team-high 8.5 APG to lead the Boilermakers in assists up to this point in the year. Fletcher Loyer has 17 PPG and Oscar Cluff’s added 11.5 PPG with 11 RPG to cap off the group of double-digit scorers for Purdue up to this point in the year. As a team, Purdue is averaging 88.3 PPG on 48.5% shooting from the field, 40.7% from three and 74% from the foul line this season.

Texas Tech Red Raiders Recap

The Texas Tech Red Raiders come into this game looking to add on to an 84-83 win over Wake Forest last time out to sit at 4-1 this season.

Red Raiders Narrowly Shake Off Wake Forest

Entering Thursday’s game with Wake Forest, JT Toppin leads the Red Raiders in scoring and rebounding with 24.3 PPG and 11.7 RPG along with 3 RPG and 2 SPG while Christian Anderson has 19.5 PPG with 4.3 RPG and team-highs of 9 APG and 2.8 SPG. Donovan Atwell has 15.3 PPG with 4 RPG, LeJuan Watts has 14 PPG with 6.3 RPG and Leon Horner has 10 PPG with 3 RPG to cap off the group of double-digit scorers for Texas Tech up to this point in the year. Tyeree Bryan also has 8.8 PPG with 4.8 RPG as well on the year. As a team, Texas Tech is averaging 88.3 PPG on 46.1% shooting from the field, 38.1% from three and 70.2% from the foul line this season.

Texas Tech Red Raiders @ Purdue Boilermakers Betting Trends: November 21, 2025


Why the Purdue Boilermakers will win

  • Texas Tech has lost each of its last eight games against Top 5 AP-ranked opponents.
  • Purdue has won eight of its last nine games against non-Conference opponents.
  • Texas Tech has lost the first half in each of its last nine night games against Top 5 AP-ranked opponents.

Why the Texas Tech Red Raiders will win

  • Texas Tech has won each of its last 11 Friday games against non-Conference opponents.
  • Purdue has lost each of its last four games against AP-ranked opponents at a neutral venue.
  • Texas Tech has won the first half in nine of its last 11 night games against non-Conference opponents.

Matchup/League Facts

  • Purdue ranks 6th among Division 1 teams for assist to turnover ratio this season (2.17).
  • Purdue ranks 356th among Division 1 teams for opponent three-point field goal attempts per game this season (31.2).
  • Texas Tech ranks T12th among Division 1 teams for opponent assists per game this season (8.8).
  • Texas Tech ranks T17th among Division 1 teams for three-point field goals made per game this season (12.0).

Purdue Boilermakers vs. Texas Tech Red Raiders Prediction

I’m on Texas Tech and the points here. I think Texas Tech is one of the most talented teams in the country, and while Purdue has that perfect blend of size, experience and skill from anywhere on the floor, I think that Texas Tech has the talent and size to match Purdue and this feels like a game that comes down to which team gets the final shot. Give me the points with Tech here.

Chris Ruffolo's Pick: Texas Tech +4.5

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