Jeremy Dent-Smith, 25, of Stanford shoots over Robbie Avila, 21, of St. Louis University in the Acrisure Invitational Champioship game at Acrisure Arena in Palm Desert, Calif., Nov. 28, 2025.
Jay Calderon/The Desert Sun / USA TODAY NETWORK via Imagn Images

St. Joseph’s vs St. Louis Prediction 12/31/2025 Today’s College Basketball Picks

Pick details

MATCHUP St. Joseph's Hawks St. Louis Billikens
Team Records 8-5 12-1
Spread +20.5 -105 -20.5 -115
Moneyline +1500 -3600
Total Over 159.5 (-112) Under 159.5 (-108)
Where Chaifetz Arena, St. Louis, MO
When Wednesday, December 31, 2025
Time 04:00 PM EST
TV ESPN+

The Saint Joseph’s Hawks and the Saint Louis Billikens meet Wednesday in college basketball action from the Chaifetz Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Saint Joseph’s Hawks vs. Saint Louis Billikens prediction.

Saint Joseph’s Hawks Recap

The Saint Joseph’s Hawks come into this game looking to build on their 87-65 win over subdivision Arcadia last time out to sit at 8-5 this year. After this game, Saint Joseph’s will head home for a game against Davidson.

Hawks Alternate Wins & Losses In 5 Straight

Deuce Jones leads the Hawks in scoring with 17 PPG while Derek Simpson has 11.9 PPG along with team-highs of 5.5 RPG and 3.4 APG to lead the Hawks in rebounding and assists. Jaiden Glover-Toscano has 12.1 PPG with 4.3 RPG to cap off the trio of double-digit scorers for Saint Joseph’s so far this season. Dasear Haskins has 8.8 PPG with 4.8 RPG while Anthony Finkley has 7.4 PPG with 3.4 RPG and Austin Williford has 6 PPG with 4.4 RPG. As a team, Saint Joseph’s is averaging 76.1 PPG on 42.3% shooting from the field, 26.3% from three and 80.4% from the foul line this season.

Saint Louis Billikens Recap

The Saint Louis Billikens come into this game looking to add on to their 114-33 rout of subdivision Principia last time out to sit at 12-1 this season. After this game, Saint Louis will head on the road for a game against VCU.

Billikens Win 6 In A Row

Dion Brown leads the Billikens in scoring and rebounding with 12.6 PPG and 7.1 RPG while Amari McCottry has 12.2 PPG with 5.3 RPG and 3 APG as well this season. Robbie Avila has 12.1 PPG with 4.6 RPG and a team-high 3.4 APG to lead the Billikens in assists while Trey Green has 12 PPG with 3.3 RPG and Quentin Jones has 10.2 PPG with 4.1 RPG and 2.7 APG to round out the group of double-digit scorers for Saint Louis so far this season. Kellen Thames has 8.9 PPG with 5 RPG while Ishan Sharma has 8.6 PPG with 3.1 RPG as well on the year. As a team, Saint Louis is averaging 90.9 PPG on 50.5% shooting from the field, 34.9% from three and 80.3% from the foul line this season.

Saint Joseph’s Hawks @ Saint Louis Billikens Betting Trends: December 31, 2025


Why the Saint Louis Billikens will win

  • Saint Louis has won each of its last 13 games at Chaifetz Arena.
  • Saint Louis has won the first half in each of its last 10 games at Chaifetz Arena.

Why the Saint Joseph’s Hawks will win

  • Saint Joseph’s has won each of its last four day games.
  • Saint Joseph’s has won the first half in each of its last three day games.

Total Points Facts

  • Each of Saint Joseph’s’ last seven games have produced a total of 152 or fewer points.
  • Twenty-one of Saint Louis’ last 23 games against Conference opponents have produced a total of 158 or fewer points.

Matchup/League Facts

  • Saint Louis ranks 2nd among Division 1 teams for point differential per game this season (+27.8).
  • Saint Louis ranks 2nd among Division 1 teams for rebound percentage this season (60.4%).
  • Saint Joseph’s ranks 361st among Division 1 teams for three-point percentage this season (27.4%).
  • Saint Joseph’s ranks T16th among Division 1 teams for opponent free throw percentage this season (65.6%).

Saint Joseph’s Hawks vs. Saint Louis Billikens Prediction

I’m backing Saint Louis here. It’s a huge number, but the thing is that the Billikens are the best team in the A-10 in my eyes, and Saint Louis has had no problem drilling inferior teams at home all year long. Am I worried about a look-ahead against VCU on deck? Maybe, but the Billikens should have no issues in this game at the end of the day so give me Saint Louis in this one.

Chris Ruffolo's Pick: Saint Louis -19.5

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