San Francisco vs Minnesota Prediction 11/22/2025 Today’s College Basketball Picks

The San Francisco Dons and the Minnesota Golden Gophers meet Saturday in college basketball action from the Sanford Pentagon. We will look at this from a betting perspective and determine the best bets for this game. Here’s a San Francisco Dons vs. Minnesota Golden Gophers prediction.

San Francisco Dons Recap

The San Francisco Dons come into this game looking to build on their 84-64 win over Northwestern State last time out to sit at 4-1 this season.

Dons Win 3 In A Row

Ryan Beasley leads the Dons in scoring with 14 PPG along with 2.8 RPG and 2.8 APG while Mookie Cook has 13.2 PPG with 6.2 RPG. Tyrone Riley IV has 10.6 PPG with 4.8 RPG and David Fuchs has 10.2 PPG with a team-high 6.6 RPG to lead the Dons in rebounding and to cap off the group of double-digit scorers for San Francisco up to this point in the year. Legend Smiley has 8.2 PPG and Vukasin Masic also has a team-high 4.2 APG to lead the Dons in assists. As a team, San Francisco is averaging 81.4 PPG on 48.2% shooting from the field, 39.7% from three and 72% from the foul line this season.

Minnesota Golden Gophers Recap

The Minnesota Golden Gophers come into this game looking to add on to their 66-54 win over Chicago State last time out to sit at 4-1 this season.

Golden Gophers Win Back-To-Back Games

Cade Tyson leads the Golden Gophers in scoring wtih 23.4 PPG along with 4.4 RPG while Jaylen Crocker-Johnson has 12 PPG with a team-high 12 RPG to lead the Gophers in rebounding by averaging a double-double per game. Isaac Asuma has 10.6 PPG with 4.8 APG to lead the Golden Gophers in assists and to cap off the trio of double-digit scorers for Minnesota so far this season. Langston Reynolds has 8.8 PPG with 4.2 RPG and 2.8 APG as well up to this point in the year. As a team, Minnesota is averaging 76 PPG on 44.9% shooting from the field, 27.3% from three and 68% from the foul line so far this season. 

San Francisco Dons @ Minnesota Golden Gophers Betting Trends: November 22, 2025

Why the Minnesota Golden Gophers will win

• Minnesota has won each of its last 13 Saturday day games against non-Conference opponents.
• San Francisco has lost each of its last four day games.
• Minnesota has won the first half in four of its last five day games against non-Conference opponents.

Why the San Francisco Dons will win

• Minnesota has lost each of its last six games played at neutral venues.
• San Francisco has won four of its last five games.
• San Francisco has won the first half in 13 of its last 14 games against non-AP-ranked opponents at a neutral venue.

Total Points Facts

• Ten of San Francisco’s last 11 games have produced a total of 146+ points.
• Each of Minnesota’s last five games against non-Conference opponents at neutral venues have produced a total of 134 or fewer points.

Matchup/League Facts

• Minnesota ranks T9th among Division 1 teams for opponent three-point field goal attempts per game this season (17.0).
• Minnesota ranks T16th among Division 1 teams for opponent free throw percentage this season (62.5%).
• San Francisco ranks 29th among Division 1 teams for opponent field goal percentage this season (36.8%).
• San Francisco ranks 30th among Division 1 teams for three-point percentage this season (39.7%).

San Francisco Dons vs. Minnesota Golden Gophers Prediction

I’m on San Francisco here. I just think the Dons are the better team by a fair margin here even though the Gophers are the power conference team in this matchup. I haven’t been all that impressed with Minnesota to this point and I think San Francisco is still a really good team that’s just unfortunately in the shadows of Gonzaga and Saint Mary’s in the WCC. I’ll lay the bucket with San Francisco in this one.

Chris Ruffolo's Pick: San Francisco -2.5