Oregon guard Jackson Shelstad puts up a shot as the Oregon Ducks host the South Dakota State Jackrabbits on Nov. 12, 2025, at Matthew Knight Arena in Eugene, Oregon.
Ben Lonergan/The Register-Guard / USA TODAY NETWORK via Imagn Images

San Diego State vs Oregon Prediction 11/25/2025 Today’s College Basketball Picks

Pick details

MATCHUP San Diego State Aztecs Oregon Ducks
Team Records 2-2 4-1
Spread +3.5 -115 -3.5 -105
Moneyline +140 -166
Total Over 143.5 (-110) Under 143.5 (-110)
Where Michelob ULTRA Arena, Las Vegas, NV
When Tuesday, November 25, 2025
Time 11:00 PM EST
TV TNT

The Oregon Ducks and the San Diego State Aztecs meet Tuesday in college basketball action from the Michelob Ultra Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Oregon Ducks vs. San Diego State Aztecs prediction.

Oregon Ducks Recap

The Oregon Ducks come into this game looking to rebound from their 84-73 loss at the hands of Auburn in their last game to sit at 4-1 so far this season. 

Ducks Looking To Shake Off First Loss Of The Season

Nate Bittle leads the Ducks in scoring and rebounding with 17 PPG and 9.2 RPG while Jackson Shelstad has 16 PPG with 3.3 RPG and a team-high 5.8 APG to lead the Ducks in assists up to this point in the year. Takai Simpkins has 15.6 PPG with 2.6 RPG and Kwame Evans Jr. has 10 PPG with 7 RPG to cap off the group of double-digit scorers for Oregon so far this season. As a team, Oregon is averaging 74 PPG on 39.9% shooting from the field, 30.5% from three and 69.7% from the foul line so far this season.

San Diego State Aztecs Recap

The San Diego State Aztecs come into this one looking to shake off a 94-54 beatdown loss at the hands of Michigan in their last game. 

Aztecs Drop Back-To-Back Games

Magoon Gwath has 13.5 PPG with 4.5 RPG while Reese Dixon-Waters has 12 PPG with 5 RPG and Miles Byrd has 11.5 PPG with 3.3 RPG and a team-high 3 APG to lead the Aztecs in assists so far this season. Elzie Harrington has 10 PPG with 2.3 APG to cap off the group of double-digit scorers for San Diego State so far this season. BJ Davis has 8.8 PPG and Jeremiah Oden’s added 8 PPG while Miles Heide has a team-high 6.8 RPG to lead the Aztecs on the glass so far this season. As a team, San Diego State is averaging 77.8 PPG on 43.5% shooting from the field, 38.4% from three and 73.7% from the foul line so far this season.

San Diego State Aztecs @ Oregon Ducks Betting Trends: November 25, 2025

Why the Oregon Ducks will win

  • Oregon has won each of its last 12 games against non-AP-ranked opponents.
  • San Diego State has lost each of its last three games played at neutral venues.
  • Oregon has won the first half in 11 of its last 12 games against non-AP-ranked opponents.

Why the San Diego State Aztecs will win

  • San Diego State has won five of its last six night games against non-AP-ranked opponents at a neutral venue.
  • Oregon has lost each of its last three games at Michelob Ultra Arena.
  • San Diego State has won the first half in six of its last seven night games against non-AP-ranked opponents at a neutral venue.

Total Points Facts

  • Eleven of Oregon’s last 13 games against non-Conference opponents at neutral venues have produced a total of 146+ points.
  • Twenty-one of San Diego State’s last 25 games against non-AP-ranked opponents at a neutral venue have produced a total of 143 or fewer points.

Matchup/League Facts

  • Oregon ranks T30th among Division 1 teams for free throw attempts per game this season (28.4).
  • Oregon ranks T43rd among Division 1 teams for rebounds per game this season (42.2).
  • San Diego State ranks T31st among Division 1 teams for opponent turnovers per game this season (16.5).
  • San Diego State ranks 45th among Division 1 teams for three-point percentage this season (38.4%).

Oregon Ducks vs. San Diego State Aztecs Prediction

I’m on San Diego State here. I just think the Aztecs are still a solid group despite not showing up on Monday, and despite not being able to win this Players Era festival tournament, I think the Aztecs want to make amends for that horrendous effort agianst Michigan. Oregon’s a solid team, but I think that the Ducks have issues with San Diego State’s physicality here and I think the Aztecs get the cover here.

Chris Ruffolo's Pick: San Diego State +3.5

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