San Diego State vs Grand Canyon Prediction 1/21/2026 Today’s College Basketball Picks

The San Diego State Aztecs and the Grand Canyon Antelopes meet Wednesday in college basketball action from GCU Arena in Phoenix. Here’s a San Diego State vs Grand Canyon prediction. We will look at this from a betting perspective and determine the best San Diego State vs Grand Canyon pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

San Diego State Aztecs Betting Preview

The Aztecs got off to a pretty decent start over their first 10 games this year, notching a 6-4 run with losses to Troy, Michigan, Baylor and Arizona in that time. San Diego State has since recorded wins over Whittier, San Jose State, Boise State, Nevada, Fresno State, Wyoming and New Mexico in the last seven outings. That gives the team a 13-4 overall record in the books this season so far.

On Saturday in the New Mexico game the Aztecs entered the second half with a 48-35 edge on the scoreboard. San Diego State was outscored 44-35 the rest of the way but managed to hang on all the same for an 83-79 victory in the end. Miles Byrd posted 21 points with eight rebounds and three assists while Pharaoh Compton chipped in 12 points with three rebounds in the winning effort.

Grand Canyon Antelopes Betting Preview

Over on the Antelopes’ side, they opened up the season on a rocky 5-4 run. Those losses came courtesy of Youngstown State, Saint Louis, Iowa and Oklahoma State. Grand Canyon is 6-2 in the last eight games though, taking wins over Coastal Carolina, Wyoming, IUPUI, Boise State, San Jose State and Utah State in that time. That gives the Lopes an 11-6 record through their first 17 games this season.

In the Utah State matchup back on Saturday the Lopes were in the locker room with a 42-36 edge. Grand Canyon scored another 42 points in the second half on the way to an 84-74 win in the end. Brian Moore put up 20 points with four rebounds and four assists while Makaih Williams had 20 points with four rebounds and three assists. Nana Owusu-Anane doubled up on 11 points and 11 boards as well.

San Diego State Aztecs @ Grand Canyon Antelopes Betting Trends: January 21, 2026

Why the Grand Canyon Antelopes will win

• Grand Canyon has won 38 of its last 41 games at Global Credit Union Arena at GCU against non-AP-ranked opponents.

Why the San Diego State Aztecs will win

• San Diego State has won each of its last eight night games against non-AP-ranked opponents.

San Diego State vs Grand Canyon Prediction

I’ll stick with San Diego State. The Aztecs put up a nice win over a pretty good New Mexico team over the weekend, shooting 49.1 percent from the field with a 36-35 rebounding edge. San Diego State got outmuscled in the paint 28-24 though, and had 15 turnovers along the way. Still, the Aztecs are looking pretty good these days with seven straight wins in the bag. SDSU has scored 71 or more points in every one of those outings as well.

As for Grand Canyon, they shot very well (50.9 percent) from the field and had a 32-28 edge in the paint during their win over Utah State. The Lopes held the Aggies to just 36.2 percent shooting from the field on the other side as well. Grand Canyon is 3-1 in the last four games with 75 or more points scored in all three wins. They could give the Aztecs some trouble here in a home matchup. It’ll be a fun one to watch.

Andrew Jett's Pick: San Diego State Aztecs -1.5