Oklahoma State vs Iowa State Prediction 1/10/2026 Today’s College Basketball Picks

The Oklahoma State Cowboys and the Iowa State Cyclones meet Saturday in college basketball action from the Hilton Coliseum. We will look at this from a betting perspective and determine the best bets for this game. Here’s an Oklahoma State Cowboys vs. Iowa State Cyclones prediction.

Oklahoma State Cowboys Recap

The Oklahoma State Cowboys come into this game looking to add on to their 87-76 win over UCF last time out to sit at 13-2 this season. After this game, Oklahoma State will head home for a game against Baylor.

Cowboys Win 8 Of Last 10

Anthony Roy leads the Cowboys in scoring with 15.5 PPG along with 3.8 RPG while Vyctorius Miller has 15.3 PPG with 2.7 RPG and 2 APG. Jaylen Curry has 13.4 PPG with 4.2 RPG and a team-high 5.3 APG to lead the Cowboys in assists up to this point in the year. Parsa Fallah has 13.1 PPG with 5.8 RPG to lead the Cowboys in rebounding and Christian Coleman has 11.8 PPG with 4.7 RPG to round out the group of double-digit scorers for OK State so far this season. Kanye Clary has 7.8 PPG with 4.5 APG and Isaiah Coleman has 7 PPG with 4.5 RPG as well this season. As a team, Oklahoma State is averaging 89.9 PPG on 49.4% shooting from the field, 32.1% shooting from three and 75.3% from the foul line this season.

Iowa State Cyclones Recap

The Iowa State Cyclones come into this game looking to add on to their 70-60 win over Baylor last time out to sit at 15-0 this season. After this game, Iowa State will head on the road for a game against Kansas.

Cyclones Looking To Stay Undefeated

Joshua Jefferson leads the Cyclones with 18.1 PPG, 7.1 RPG and 5 APG while Milan Momcilovic has 17.9 PPG with 3.2 RPG and Tamin Lipsey has 14.2 PPG with 3.8 RPG and 6 APG along with 2.6 SPG. Killyan Toure has 11 PPG with 3.2 RPG and 2.8 APG to cap off the group of double-digit scorers for Iowa State so far this season. Blake Buchanan has 9.9 PPG with 6.7 RPG as well this season. As a team, Iowa State is averaging 90.4 PPG on 53.2% shooting from the field, 41% from three and 68.9% from the foul line this season.

Oklahoma State Cowboys @ Iowa State Cyclones Betting Trends: January 10, 2026

Why the Iowa State Cyclones will win

• Iowa State has won each of its last 20 games at James H. Hilton Coliseum when playing with a rest disadvantage.
• Oklahoma State has lost each of its last 10 Saturday road games against Conference opponents.
• Iowa State has won the first half in 28 of its last 30 day games at James H. Hilton Coliseum.

Why the Oklahoma State Cowboys will win

• Oklahoma State has won each of its last eight games when playing with a rest advantage.
• Iowa State has lost nine of its last 12 January day games as a top-15 AP-ranked team against a non-AP-ranked team.
• Iowa State has lost the first half in each of its last four day games as a top-3 AP-ranked team.

Total Points Facts

• Each of Iowa State’s last 25 day games against Conference opponents at James H. Hilton Coliseum have produced a total of 156 or fewer points.
• Each of Oklahoma State’s last 18 games against Top 10 AP-ranked opponents have produced a total of 164 or fewer points.

Matchup/League Facts

• Iowa State ranks 2nd among Division 1 teams for net rating this season (+37.3).
• Iowa State ranks 4th among Division 1 teams for point differential per game this season (+25.9).
• Oklahoma State ranks 4th among Division 1 teams for pace this season (76.8).
• Oklahoma State ranks 359th among Division 1 teams for opponent three-point field goal attempts per game this season (30.7).

Oklahoma State Cowboys vs. Iowa State Cyclones Prediction

I’m on the Cowboys and the points here. I get why Iowa State is a heavy favorite at home with an all-around game that can see you blink and have Iowa State up by 25. That being said, the Cyclones have left a lot of points at the foul line as of late, and that could be a problem here against an Oklahoma State team that’s got size and balance and more than enough talent to keep this game within reason. Give me Oklahoma State and the points in this one.

Chris Ruffolo's Pick: Oklahoma State +19