Mar 9, 2023; Las Vegas, NV, USA; A Colorado Buffaloes cheerleader entertains the crowd during a game between the Buffaloes and the UCLA Bruins during the second half at T-Mobile Arena. Mandatory Credit: Stephen R. Sylvanie-Imagn Images
Stephen R. Sylvanie-Imagn Images

Oklahoma State vs Colorado Prediction 3/10/2026 Today’s College Basketball Picks

Pick details

MATCHUP Oklahoma State Cowboys Colorado Buffaloes
Team Records 18-13 17-14
Spread +2.5 -112 -2.5 -108
Moneyline +105 -125
Total Over 164.5 (-110) Under 164.5 (-110)
Where Legacy Arena at BJCC, Birmingham, AL
When Tuesday, March 10, 2026
Time 09:30 PM EDT
TV ESPN+

The Oklahoma State Cowboys and the Colorado Buffaloes meet Tuesday in Big 12 Tournament college basketball action from T-Mobile Center in Kansas City. Here’s an Oklahoma State vs Colorado prediction. We will look at this from a betting perspective and determine the best Oklahoma State vs Colorado pick. We will examine the recent form and player performances for both teams, as well as the recent betting trends and streaks pertaining to this matchup. As we conclude, we will tie it all together with a summary that produces a sensible pick for a favorable betting outcome in this game.

Oklahoma State Cowboys Betting Preview

Oklahoma State posted a 16-6 record over their first 22 games of the season, then hit the skids on a five-game losing streak. Those defeats came versus Arizona, Arizona State, TCU, Kansas and Colorado. The Cowboys are 2-2 in the last four outings with wins over West Virginia and Central Florida mixed with losses to Cincinnati and Houston. That gives the team an 18-13 record this year.

In the Houston matchup back on Saturday the Cowboys were in front 41-37 as they came back out onto the floor for the second half. Oklahoma State hit a 45-34 deficit the rest of the way however, eventually leading to a loss 82-75 on their home court. Tops in scoring during the losing effort was Anthony Roy with 18 points, four rebounds and two assists in 35 minutes of action.

Colorado Buffaloes Betting Preview

Over on the Buffaloes’ side, they were a tepid 12-9 back at the end of January and coming off a six-game losing streak. Since then it’s been a 5-5 run for Colorado featuring wins over TCU, Arizona State, Oklahoma State, Kansas State and Utah. The losses in that time came versus Baylor, Texas Tech, BYU, Houston and Arizona. That makes for a 17-14 record this season.

Matched up against Arizona on Saturday the Buffaloes were ahead 38-36 going into the second half. Colorado got outscored 53-41 the rest of the way however, resulting in an eventual 89-79 loss on their home court. Isaiah Johnson was the top team scorer with 28 points and five assists while Barrington Hargress had 13 points with three assists and two blocks.

Oklahoma State Cowboys @ Colorado Buffaloes Betting Trends: March 10, 2026

Why the Colorado Buffaloes will win

  • Colorado has won five of its last six games against non-AP-ranked opponents.
  • Oklahoma State has lost four of its last five games against Conference opponents at T-Mobile Center.
  • Oklahoma State has lost the first half in four of its last five games at T-Mobile Center.

Why the Oklahoma State Cowboys will win

  • Oklahoma State has won each of its last three night games against non-AP-ranked opponents at a neutral venue.
  • Colorado has lost three of its last four night games played at neutral venues.
  • Oklahoma State has won the first half in six of its last eight night games against non-AP-ranked opponents at a neutral venue.

Matchup/League Facts

  • Oklahoma State ranks 22nd among Division 1 teams for field goal attempts per game this season (62.8).
  • Oklahoma State ranks 25th among Division 1 teams for points per game this season (83.9).

Oklahoma State vs Colorado Prediction

I’ll just stay with Colorado. The Buffaloes couldn’t keep pace with a great Arizona team over the weekend in a loss at Coors Events Center, shooting just 40.6 percent from the field with 55.9 percent surrendered on the other side. Colorado was out-rebounded 34-30 and outscored in the paint 54-26 during the defeat. The Buffs are just 1-2 in the last three games but the losses came to top-five teams in Houston and Arizona.

These teams last met back on February 21 in an 83-69 victory at home for the Buffaloes. In that one Colorado shot well with 47.5 percent from the field versus just 37.7 percent surrendered by the defense. It was a sloppy game though, with the Buffaloes accounting for 12 of the overall 25 turnovers. Provided Colorado can clean up the mistakes a bit in this tournament rematch they should be set up well.

Andrew Jett's Pick: Colorado Buffaloes -1.5

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