Oklahoma State vs Colorado Prediction 2/21/2026 Today’s College Basketball Picks

In this article we will formulate an Oklahoma State vs Colorado prediction for this College Basketball game on Saturday, February 21st at the CU Events Center in Boulder, Colorado. Let’s take a look at the prediction for this College Basketball matchup.

Oklahoma State Cowboys Betting Preview

The Oklahoma State Cowboys are 16-10 (4-9) this season after they lost to Kansas by a score of 81-69 in their last game. Oklahoma State trailed 43-29 at halftime, but did win the second half 40-38 in the loss. The Cowboys shot 35% from the field, 25% on three pointers, and 76% on free throws in the game. Parsa Fallah led Oklahoma State with 21 points and four rebounds, while Anthony Roy added 16 points and four rebounds in the loss. 

Prior to that game, Oklahoma State lost to TCU by a score of 95-92 and Arizona State by a score of 85-76. The Cowboys have scored 84.1 points per game with 37.7 rebounds and 15.3 assists per game, while they have allowed 81.3 points against per game this season. Anthony Roy is averaging 17.5 points and 3.9 rebounds per game, while Parsa Fallah is averaging 14.5 points and 6.1 rebounds per game for the Cowboys. Oklahoma State is shooting 46.3% from the field, 73.4% on free throws, and 34.2% on three pointers this season. 

Colorado Buffaloes Betting Preview

The Colorado Buffaloes are 14-12 (4-9) this year after they lost to BYU in overtime by a score of 90-86 in their last game. Colorado trailed 37-32 at halftime, but they scored 46 points in the second half, before losing in overtime. The Buffaloes shot 44% from the field, 28% on three pointers, and 61% on free throws in the game. Isaiah Johnson led Colorado with 27 points and four assists, while Barrington Hargress added 20 points and five rebounds in the loss. 

Prior to that game, Colorado lost to Texas Tech by a score of 78-44, but did beat Arizona State by a score of 78-70 before that. The Buffaloes have scored 80.0 points per game with 34.7 rebounds and 15.5 assists per game, while they have allowed 78.5 points against per game this season. Isaiah Johnson is averaging 16.5 points and 2.6 assists per game, while Barrington Hargress is averaging 14.1 points and 4.3 assists per game for the Buffaloes. Colorado is shooting 46.9% from the field, 75.1% on free throws, and 35.0% on three pointers this year. 

Why the Colorado Buffaloes will win

• Colorado has won 25 of its last 27 day games at CU Events Center against non-AP-ranked opponents.
• Oklahoma State has lost each of its last four games.
• Oklahoma State has lost the first half in each of its last four games against Conference opponents.

Why the Oklahoma State Cowboys will win

• Colorado has lost nine of its last 11 games against Conference opponents.

Total Points Facts

• Sixteen of Oklahoma State’s last 18 day games against Conference opponents have produced a total of 160 or fewer points.
• Thirty-one of Colorado’s last 36 games against Conference opponents have produced a total of 158 or fewer points.

Oklahoma State vs Colorado Prediction 

Both of these teams come into this matchup with a 4-9 conference record, but Colorado will be at home. The Buffaloes are shooting 47% from the field and they have allowed at least 78 points in three of their last four games. The Cowboys are shooting 46% from the field and they have allowed 81+ points in five straight. Both teams are similar on offense, but I don’t trust this Oklahoma State defense at all. Take Colorado to cover at home.

David Racey's Pick: Colorado -3.5