Nov 24, 2025; Louisville, Kentucky, USA; Eastern Michigan Eagles guard Mehki Ellison (3) dribbles against Louisville Cardinals guard Mikel Brown Jr. (0) during the second half at KFC Yum! Center. Louisville defeated Eastern Michigan 87-46. Mandatory Credit: Jamie Rhodes-Imagn Images
Jamie Rhodes-Imagn Images

Louisville vs Arkansas Prediction 12/3/2025 Today’s College Basketball Picks

Pick details

MATCHUP Louisville Cardinals Arkansas Razorbacks
Team Records 7-0 5-2
Spread -2.5 -110 +2.5 -110
Moneyline -142 +120
Total Over 165.5 (-108) Under 165.5 (-112)
Where Bud Walton Arena, Fayetteville, AR
When Wednesday, December 3, 2025
Time 07:15 PM EST
TV ESPN

In this article we will formulate a Louisville vs Arkansas prediction for this College Basketball game on Wednesday, December 3rd at Bud Walton Arena in Fayetteville, Arkansas. Let’s take a look at the prediction for this College Basketball matchup.

Louisville Cardinals Betting Preview

The Louisville Cardinals are 7-0 this season after they defeated NJIT by a score of 104-47 in their last game. Louisville led 52-20 at halftime and added 52 more points in the second half for the lopsided win. The Cardinals shot 49% from the field, 42% on three pointers, and 86% on free throws in the game. Ryan Conwell led Louisville with 32 points and nine rebounds, while Isaac McKneely added 17 points and three rebounds in the win. 

Prior to that game, Louisville defeated Eastern Michigan by a score of 87-46 and Cincinnati by a score of 74-64. The Cardinals have scored 96.7 points per game with 46.0 rebounds and 20.7 assists per game, while they have allowed 63.0 points against per game this season. Ryan Conwell is averaging 20.1 points and 5.4 rebounds per game, while Mikel Brown Jr is averaging 17.0 points and 6.0 assists per game for the Cardinals. Louisville is shooting 48.1% from the field, 75.8% on free throws, and 37.3% on three pointers this season. 

Arkansas Razorbacks Betting Preview

The Arkansas Razorbacks are 5-2 this year after they lost to Duke by a score of 80-71 in their last game. Arkansas trailed 41-35 at halftime, but did battle hard in the second half to keep the game close. The Razorbacks shot 41% from the field, 33% on three pointers, and 82% on free throws in the game. Darius Acuff Jr led Arkansas with 21 points and five assists, while Meleek Thomas added 13 points and two assists in the loss. 

Prior to that game, Arkansas defeated Jackson State by a score of 115-61 and Winthrop by a score of 84-83. The Razorbacks have scored 88.1 points per game with 37.9 rebounds and 17.6 assists per game, while they have allowed 71.6 points against per game this season. Meleek Thomas is averaging 17.6 points and 4.6 rebounds per game, while Darius Acuff Jr is averaging 17.4 points and 4.4 assists per game for the Razorbacks. Arkansas is shooting 48.5% from the field, 80% on free throws, and 35.5% on three pointers this year. 

Why the Arkansas Razorbacks will win

  • Arkansas has won each of its last 14 night games against non-Conference opponents at Bud Walton Arena.
  • Louisville has lost 20 of its last 23 games against AP-ranked opponents.
  • Louisville has lost the first half in four of its last five night games against the Southeastern Conference.

Why the Louisville Cardinals will win

  • Louisville has won each of its last eight games when playing with a rest advantage.
  • Arkansas has lost 10 of its last 11 games against Top 10 AP-ranked opponents.
  • Arkansas has lost the first half in eight of its last 10 games against Top 10 AP-ranked opponents.

Total Points Facts

  • Each of Arkansas’ last seven night games against the Atlantic Coast Conference have produced a total of 155 or fewer points.
  • Thirty-eight of Louisville’s last 42 games against AP-ranked opponents have produced a total of 161 or fewer points.

Louisville vs Arkansas Prediction 

Louisville comes into this matchup looking to stay undefeated on the season, but this is going to be a tough road game. The Cardinals are shooting 48% from the field and they have scored at least 87 points in four of their last five. Arkansas had their winning streak snapped against Duke last time out, but they actually played pretty well in that game. The Razorbacks are shooting 49% from the field and they have scored at least 84 in three of their last five. I do think Louisville is the slightly better team, but I think Arkansas is going to play a complete game for a huge home win.

David Racey's Pick: Arkansas ML

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