Iowa State vs BYU Prediction 2/21/2026 Today’s College Basketball Picks

In this article we will formulate an Iowa State vs BYU prediction for this College Basketball game on Saturday, February 21st at the Marriott Center in Provo, Utah. Let’s take a look at the prediction for this College Basketball matchup.

Iowa State Cyclones Betting Preview

The Iowa State Cyclones are 23-3 (10-3) this season after they defeated Houston by a score of 70-67 in their last game. Iowa State led 43-40 at halftime and they held Houston to just 27 points in the second half for the win. The Cyclones shot 49% from the field, 41% on three pointers, and 50% on free throws in the game. Joshua Jefferson led Iowa State with 12 points and six rebounds, while Nate Heise added 11 points and six rebounds in the win. 

Prior to that game, Iowa State defeated Kansas by a score of 74-56, but lost to TCU by a score of 62-55 before that. The Cyclones have scored 83.7 points per game with 36.4 rebounds and 18.1 assists per game, while they have allowed 64.6 points against per game this season. Milan Momcilovic is averaging 18.0 points and 3.2 rebounds per game, while Joshua Jefferson is averaging 16.5 points and 7.5 rebounds per game for the Cyclones. Iowa State is shooting 50.5% from the field, 66.5% on free throws, and 39.8% on three pointers this season. 

BYU Cougars Betting Preview

The BYU Cougars are 19-7 (7-6) this year after they lost to Arizona by a score of 75-68 in their last game. BYU trailed 42-35 at halftime, but they tied the second half at 33 in the loss. The Cougars shot 43% from the field, 26% on three pointers, and 81% on free throws in the game. AJ Dybantsa led BYU with 35 points and seven rebounds, while Robert Wright III added 13 points and four rebounds in the loss. 

Prior to that game, BYU defeated Colorado by a score of 90-86 and Baylor by a score of 99-94. The Cougars have scored 85.8 points per game with 39.2 rebounds and 14.4 assists per game, while they have allowed 74.5 points against per game this season. AJ Dybantsa is averaging 24.8 points and 6.6 rebounds per game, while Robert Wright III is averaging 18.5 points and 4.8 assists per game for the Cougars. BYU is shooting 48.3% from the field, 74.4% on free throws, and 35.5% on three pointers this year. 

Why the BYU Cougars will win

• Iowa State has lost nine of its last 10 February road games as an AP-ranked team against an AP-ranked team.
• BYU has won 17 of its last 19 games as an AP-ranked team at Marriott Center.
• BYU has won the first half in 21 of its last 26 night games at Marriott Center.

Why the Iowa State Cyclones will win

• BYU has lost each of its last six games at Marriott Center against Top 10 AP-ranked opponents.
• Iowa State has won 23 of its last 26 games.
• BYU has lost the first half in each of its last six games at Marriott Center against Top 10 AP-ranked opponents.

Total Points Facts

• Each of Iowa State’s last 13 Saturday games against the Big 12 Conference Conference have produced a total of 155 or fewer points.
• Five of BYU’s last six night games against Top 10 AP-ranked opponents at Marriott Center have produced a total of 153 or fewer points.

Matchup/League Facts

• BYU ranks T28th among Division 1 teams for blocks per game this season (4.8).
• BYU ranks 31st among Division 1 teams for offensive rating this season (120.7).
• Iowa State ranks T7th among Division 1 teams for opponent free throws made per game this season (10.5).
• Iowa State ranks 7th among Division 1 teams for defensive rating this season (95.1).

Iowa State vs BYU Prediction 

BYU comes into this matchup after winning two of their last three games, but they haven’t played their best over the last three weeks. The Cougars are shooting 48% from the field and they have allowed at least 86 points in three of their last five. Iowa State is 10-3 in Big 12 play and they just got a huge win over Houston. The Cyclones are shooting 51% from the field and they have allowed fewer than 70 points in four of their last five. BYU is missing their third leading scorer, but they are at home and Iowa State has been pretty bad at free throws, which is going to cost them eventually. Take the Cougars here.

David Racey's Pick: BYU +2.5