Duquesne vs Northeastern Prediction 11/22/2025 Today’s College Basketball Picks

The Duquesne Dukes and the Northeastern Huskies meet Saturday in college basketball action from the LeBron James Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Duquesne Dukes vs. Northeastern Huskies prediction.

Duquesne Dukes Recap

The Duquesne Dukes come into this game looking to build on a 92-78 win over Loyola-Maryland last time out to sit at 4-1 this season.

Dukes Looking To Build More Momentum

Tarence Guinyard leads the Dukes in scoring and assists with 20.6 PPG and 5.8 APG along with 2.2 SPG while John Hugley IV has 17.4 PPG with 6.6 RPG and 2.4 APG to lead Duquesne in rebounding. Jimmie Williams has 11.2 PPG with 4.8 RPG and 2 APG to cap off the trio of double-digit scorers for Duquesne up to this point in the year. Maximus Edwards has 8.2 PPG with 3 RPG as well on the year. As a team, Duquesne is averaging 86.2 PPG on 50.3% shooting from the field, 33.1% from three and 67.2% from the foul line so far this season.

Northeastern Huskies Recap

The Northeastern Huskies come into this game looking to bounce back from their 70-57 loss at the hands of the Princeton Tigers last time out to sit at 2-3 this season. 

Huskies Drop Back-To-Back Games

LA Pratt has 17 PPG with 3.3 APG and 2.3 SPG while Youri Fritz has 16.2 PPG with 7.4 RPG and Xander Alane has 11.2 PPG with a team-high 8.8 RPG to lead the Huskies in rebounding and to cap off the group of double-digit scorers for Northeastern so far this season. William Kermoury has 7 PPG with 2.8 RPG and Luca Soroa Schaller has 6.5 PPG with 3 RPG and a team-high 4.3 APG as well this season to lead the Huskies in assists. As a team, Northeastern is averaging 70.2 PPG on 42.2% shooting from the field, 26.8% from three and 68.1% from the foul line this season.

Duquesne Dukes @ Northeastern Huskies Betting Trends: November 22, 2025

Why the Northeastern Huskies will win

• Duquesne has lost five of its last six day games.
• Northeastern has won three of its last four games against non-Conference opponents at neutral venues.
• Northeastern has won the first half in nine of its last 12 day games against non-AP-ranked opponents at a neutral venue.

Why the Duquesne Dukes will win

• Duquesne has won 14 of its last 15 Saturday day games against non-Conference opponents.
• Northeastern has lost three of its last four games against the Atlantic 10 Conference.
• Duquesne has won the first half in nine of its last 10 games against non-AP-ranked opponents at a neutral venue.

Total Points Facts

• Each of Duquesne’s last eight games against non-AP-ranked opponents at a neutral venue have produced a total of 143 or fewer points.
• Seventeen of Northeastern’s last 19 games against non-Conference opponents at neutral venues have produced a total of 148 or fewer points.

Matchup/League Facts

• Northeastern ranks 18th among Division 1 teams for opponent field goal attempts per game this season (53.2).
• Duquesne ranks T360th among Division 1 teams for opponent free throw attempts per game this season (30.8).
• Duquesne ranks T359th among Division 1 teams for opponent free throws made per game this season (22.0).

Duquesne Dukes vs. Northeastern Huskies Prediction

I’m on the Dukes here. I get the allure of backing Northeastern with the points after playing a bunch of solid mid-major opponents to this point but the thing is that Duquesne is another team on that list and have been really strong out of the gate this season. I think that Duquesne pulls away over the course of the second half to get the win and cover in this one.

Chris Ruffolo's Pick: Duquesne -8.5