Cincinnati vs Clemson Prediction 12/21/2025 Today’s College Basketball Picks

The Cincinnati Bearcats and the Clemson Tigers meet Sunday in college basketball action from the Bon Secours Wellness Arena. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Cincinnati Bearcats vs. Clemson Tigers prediction.

Cincinnati Bearcats Recap

The Cincinnati Bearcats come into this game looking to add on to their 88-51 win over Alabama State last time out to sit at 7-4 this season. After this game, Cincinnati will take on Lipscomb at home.

Bearcats Snap Two-Game Slide

Day Day Thomas leads the Bearcats in scoring with 13.9 PPG along with 3.8 RPG and 4.2 APG while Baba Miller has 13.6 PPG with a team-high 11.1 RPG to lead the Bearcats in rebounding by averaging a double-double per game. Shon Abaev has 12 PPG with 4.1 RPG to round out the trio of double-digit scorers for Cincinnati so far this season while Moustapha Thiam has 9.8 PPG with 7.1 RPG and Kerr Kriisa has 8.3 PPG with a team-high 4.6 APG to lead the Bearcats in assists. As a team, Cincinnati is averaging 75.3 PPG on 42.4% shooting from the field, 32% from three and 63% from the foul line so far this season.

Clemson Tigers Recap

The Clemson Tigers come into this game looking to add on to their 68-61 win over South Carolina in their last game to improve to 9-3 on the year. After this game, Clemson will head on the road for a game against Syracuse.

Tigers Win Back-To-Back Games

RJ Godfrey leads the Tigers in scoring and rebounding with 12.1 PPG and 6.4 RPG along with 2.3 APG while Carter Welling has 10.6 PPG with 6.2 RPG this season. Jestin Porter has 10.2 PPG with 2.1 RPG to cap off the trio of double-digit scorers for Clemson so far this season. Dillon Hunter has 9.2 PPG with 3.6 RPG and 2.7 APG while Nick Davidson has 8 PPG with 4.9 RPG and Jake Wahlin has 8 PPG with 4.8 RPG as well this season. Zac Foster’s added 7.8 PPG with 2.9 RPG and 2.9 APG as well to lead the Tigers in assists so far this season. As a team, Clemson is averaging 85.1 PPG on 46.3% shooting from the field, 32.8% from three and 74.9% from the foul line this season.

Cincinnati Bearcats @ Clemson Tigers Betting Trends: December 21, 2025

Why the Clemson Tigers will win

• Clemson has won each of its last six games against non-AP-ranked opponents.
• Cincinnati has lost four of its last five games played at neutral venues.
• Clemson has won the first half in each of its last five games against non-Conference opponents at Bon Secours Wellness Arena.

Why the Cincinnati Bearcats will win

• Cincinnati has won each of its last nine Sunday games against non-Conference opponents.
• Cincinnati has won the first half in each of its last seven Sunday day games against non-Conference opponents.

Total Points Facts

• Each of Clemson’s last eight games at Bon Secours Wellness Arena have produced a total of 142+ points.
• Each of Cincinnati’s last six games against non-AP-ranked opponents at a neutral venue have produced a total of 144+ points.

Matchup/League Facts

• Clemson ranks 5th among Division 1 teams for opponent three-point percentage this season (26.3%).
• Clemson ranks 5th among Division 1 teams for turnover percentage this season (11.3%).
• Cincinnati ranks T20th among Division 1 teams for blocks per game this season (5.5).
• Cincinnati ranks 23rd among Division 1 teams for opponent field goal percentage this season (38.4%).

Cincinnati Bearcats vs. Clemson Tigers Prediction

I’m on Clemson here. I just think that Clemson is the better team in this matchup by a fair margin and we’ve seen the Tigers show up and be far more consistent than what Clemson’s brought to the table for much of the season. I just feel like I know what I’m getting from Clemson a lot more than I know with Cincinnati here so I’ll back the Tigers at home here.

Chris Ruffolo's Pick: Clemson -6.5