Buffalo vs DePaul Prediction 11/11/2025 Today’s College Basketball Picks

In this article, we will formulate an Eastern Illinois vs Notre Dame Prediction for this College Basketball game on Tuesday, November 11th. Let’s take a look at the prediction for this College Basketball matchup.

DePaul Blue Demons Preview

DePaul has a 2-0 record this season. They are 1-1 ATS, 1-1 in Over/Under and have a 2-0 home record and a 0-0 away record. DePaul is coming off a 72-64 home win against Stonehill and will face Northwestern, Gardner-Webb and Detroit Mercy next.

Offensively, DePaul averages 82 points per game, which ranks 172nd in the nation, while defensively, they allow 63 points per game (79th). The Blue Demons shoot with 43.4% from the field (239th), and with 26.5% from beyond the arc (295th). They shoot with 64.3% from the free throw line (287th), and grab 41 rebounds per game (137th), while dishing out 17.5 assists per game (114th) and committing 10 turnovers per game (66th).

CJ Gunn leads DePaul in scoring, with an average of 20 points, 4.5 rebounds and 3.5 assists. N.J. Benson follows with 16 points, 10 rebounds per game, while Layden Blocker adds 10 points, 2.5 rebounds and 4 assists per game.

Buffalo Bulls Preview

Buffalo has a 2-0 record this season. They are 2-0 ATS, 2-0 in Over/Under and have a 2-0 home record and a 0-0 away record. Buffalo is coming off a 83-76 home win against Green Bay and will face RIT, Vermont and Virginia Military Institute next.

Offensively, Buffalo averages 84 points per game, which ranks 143rd in the nation, while defensively, they allow 77.5 points per game (243rd). The Bulls shoot with 49.0% from the field (113th), and with 39.1% from beyond the arc (75th). They shoot with 67.5% from the free throw line (242nd), and grab 30.5 rebounds per game (329th), while dishing out 13 assists per game (245th) and committing 7.5 turnovers per game (15th).

Ryan Sabol leads Buffalo in scoring, with an average of 20.5 points, 1.5 rebounds and 2.5 assists. Daniel Freitag follows with 13.5 points, 2.5 rebounds and 1.5 assists per game, while Derrick Talton adds 12.5 points, 3 rebounds and 4 assists per game.

Buffalo Bulls @ DePaul Blue Demons Betting Trends: November 11, 2025

Why the DePaul Blue Demons will win

• DePaul has won each of its last 12 home games against non-Conference opponents.
• Buffalo has lost each of its last six road games against non-Conference opponents.
• DePaul has won the first half in each of its last seven home night games against non-Conference opponents.

Why the Buffalo Bulls will win

• DePaul has lost each of its last six Tuesday games.
• Buffalo has won four of its last five night games against non-Conference opponents.

Buffalo vs DePaul Prediction

In this Buffalo vs DePaul Prediction, DePaul is coming as -17.5 home favorites. Both teams have been perfect this season as both have won both games played, but Depaul is playing their third consecutive game at home and is superior defensively, allowing 14.5 points per game less than Buffalo. The Blue Demons are also better both in rebounding and in assists made and they have the edge at home in this matchup. Take DePaul and lay the points at home.

Nikos Lagouretos's Pick: DePaul -17.5