Nov 17, 2025; Morgantown, West Virginia, USA; West Virginia Mountaineers guard Jayden Forsythe (4) shoots a three-point basket during the second half against the Lafayette Leopards at WVU Coliseum. Mandatory Credit: Ben Queen-Imagn Images
Ben Queen-Imagn Images

American vs Lafayette Prediction 2/22/2026 Today’s College Basketball Picks

Pick details

MATCHUP American Eagles Lafayette Leopards
Team Records 9-19
Spread -4.5 -108 +4.5 -112
Moneyline -198 +164
Total Over 140.5 (-112) Under 140.5 (-108)
Where Kirby Sports Center, Easton, PA
When Sunday, February 22, 2026
Time 12:00 PM EST
TV ESPN+

In this article we will formulate an American vs Lafayette prediction for this College Basketball game on Sunday, February 22nd at the Kirby Sports Center in Easton, Pennsylvania. Let’s take a look at the prediction for this College Basketball matchup.

American Eagles Betting Preview

The American Eagles are 15-13 (8-7) this season after they defeated Bucknell by a score of 75-57 in their last game. American led 36-30 at halftime and they held Bucknell to just 27 points in the second half in the win. The Eagles shot 40% from the field, 33% on three pointers, and 81% on free throws in the game. Madden Collins led American with 16 points and four rebounds, while Matt Mayock added 10 points and five rebounds in the win. 

Prior to that game, American defeated Army by a score of 75-63, but lost to Lehigh by a score of 90-82 before that. The Eagles have scored 75.0 points per game with 32.0 rebounds and 13.6 assists per game, while they have allowed 71.5 points against per game this season. Madden Collins is averaging 13.6 points and 5.1 rebounds per game, while Greg Jones is averaging 12.1 points and 4.5 rebounds per game for the Eagles. American is shooting 45.0% from the field, 75.7% on free throws, and 33.4% on three pointers this season. 

Lafayette Leopards Betting Preview

The Lafayette Leopards are 9-19 (6-9) this year after they defeated Holy Cross by a score of 86-83 in their last game. Lafayette trailed 49-33 at halftime, but they scored 53 points in the second half to secure the win. The Leopards shot 56% from the field, 47% on three pointers, and 70% on free throws in the game. Ryan Pettit led Lafayette with 19 points and seven rebounds, while Caleb Williams added 17 points and four rebounds in the win. 

Prior to that game, Lafayette lost to Lehigh by a score of 78-69 and Loyola (MD) by a score of 68-54. The Leopards have scored 69.0 points per game with 33.5 rebounds and 13.3 assists per game, while they have allowed 74.2 points against per game this season. Caleb Williams is averaging 16.5 points and 3.6 rebounds per game, while Andrew Phillips is averaging 14.6 points and 4.6 rebounds per game for the Leopards. Lafayette is shooting 42.2% from the field, 68.2% on free throws, and 32.1% on three pointers this year. 

Why the Lafayette Leopards will win

  • American University has lost five of its last six day games at Kirby Sports Center against non-AP-ranked opponents.
  • Lafayette has won eight of its last 10 day games against American University.
  • American University has lost the first half in three of its last four road games against non-AP-ranked opponents.

Why the American University Eagles will win

  • Lafayette has lost eight of its last nine games following a road win.
  • American University has won eight of its last nine road day games against Conference opponents.
  • American University has won the first half in eight of its last 10 day games against non-AP-ranked opponents.

Total Points Facts

  • Each of American University’s last four day games against non-AP-ranked opponents at Kirby Sports Center have produced a total of 152+ points.
  • Five of the last six day games between American University and Lafayette at Kirby Sports Center have produced a total of 152+ points.

American vs Lafayette Prediction 

American comes into this matchup on a two game winning streak and they are battling for third in the conference, but they will be on the road here. The Eagles are shooting 45% from the field and they have allowed 63 points or fewer in three of their last five games. Lafayette has dropped three of their last five games, including each of their last three home games. The Leopards are shooting 42% from the field and they have scored fewer than 70 points in four of their last five. I think we are going to see a lower scoring game here, so I like the under in this one.

David Racey's Pick: Under 140.5

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