Ohio State Buckeyes cornerback Jeff Okudah (1) tackles Wisconsin Badgers wide receiver Kendric Pryor (3) during the first quarter of a NCAA Division I college football game between the Ohio State Buckeyes and the Wisconsin Badgers on Saturday, October 26, 2019 at Ohio Stadium in Columbus, Ohio. [Joshua A. Bickel/Dispatch]

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Wisconsin vs Alabama Prediction 9/13/2025 Today’s College Football Picks

Pick details

Wisconsin (2-0) vs Alabama (1-1)

September 13, 2025 at 12:00 PM EDT

The Line: Betting Odds: Alabama -20.5 — Over/Under: +46.5

(Get latest betting odds)

In this article, we will formulate a Wisconsin vs Alabama Prediction for this College Football Week 3 game on Saturday, September 13th at the Bryant-Denny Stadium. Let’s take a look at the prediction for this College Football matchup.

Alabama Crimson Tide Preview

The Crimson Tide have a 1-1 record this season and are ranked as No.22 in the College Football Top 136 Team Rankings for 2025. Ohio State is number 1, Penn State is number 2 and LSU is number 3 in the rankings. The Crimson Tide are coming off a 73-0 home victory over UL Monroe. Alabama outgained their opponents by 583-148 yards. They had 29/33 completed passes, 371 passing yards, 212 rushing yards, with turnovers being 0-3. The Crimson Tide went 9-12 in third down efficiency and had 5-55 penalties.

Ty Simpson had 17/17 passes, a team-high 226 passing yards, three touchdowns and no interceptions. AK Dear added a team-high 76 rushing yards, while Germie Bernard caught 3 passes for 67 yards. Defensively, James Smith had 4 total tackles, four of them solo, while no Alabama player recorded a sack. Justin Jefferson had one interception.

Wisconsin Badgers Preview

The Badgers have a 2-0 record this season and are ranked as No.48 in the College Football Top 136 Team Rankings for 2025. Ohio State is number 1, Penn State is number 2 and LSU is number 3 in the rankings. The Badgers are coming off a 42-10 home victory over Middle Tennessee. Wisconsin outgained their opponents by 436-241 yards. They had 23/27 completed passes, 283 passing yards, 153 rushing yards, with turnovers being 2-1. The Badgers went 4-9 in third down efficiency and had 0-0 penalties.

anny O’Neil had 23/27 passes, a team-high 283 passing yards, three touchdowns but also threw one interception. Trech Kekahuna added a team-high 61 rushing yards, while Lance Mason caught 7 passes for 102 yards. Defensively, Christian Alliegro had 7 total tackles, six of them solo, while Tackett Curtis had one sack. Omillio Agard had one interception.

Wisconsin vs Alabama Prediction

Alabama has won both meetings against Wisconsin, having covered the spread in both, as both games went over the total. In their most recent meeting last season, the Crimson Tide won 42-10 on the road.

In this Wisconsin vs Alabama Prediction, Alabama is coming in as -21-point road favorites, with the total set at 46.5 points. Both teams are coming off big wins in the previous week, and Alabama was undefeated at home last season in their seven home games and were 7-5 ATS. Wisconsin was 4-8 against the spread last season, and this will be their first test on the road. I Like the hosts to win easily in this season, just like last season where they won by 32 points, so take the Alabama Crimson Tide and lay the points at home.

Nikos Lagouretos's Pick: Alabama -20.5

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