Ohio Bobcats quarterback Parker Navarro (13) looks for an open teammate, Thursday, August 28, 2025.

West Virginia vs Ohio Prediction 9/6/2025 Today’s College Football Picks

Pick details

West Virginia (1-0) vs Ohio (0-1)

September 6, 2025 at 04:00 PM EDT

The Line: Betting Odds: Ohio +3 — Over/Under: +59.5

(Get latest betting odds)

The West Virginia Mountaineers and the Ohio Bobcats meet in week 2 college football action from Solich Field at Peden Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a West Virginia Mountaineers vs. Ohio Bobcats prediction.

West Virginia Mountaineers Recap

The West Virginia Mountaineers come into this game looking to add on to their 45-3 win over Robert Morris last time out to improve to 1-0 to start the year. After this game, West Virginia will head home for the Backyard Brawl against Pitt.

Mountaineers Looking To Keep Momentum Going

Nicco Marchiol threw for 224 yards and a touchdown on 17 of 20 passing while Jahiem White rushed for 93 yards and 2 touchdowns on 18 carries. Scotty Fox Jr. had 63 rushing yards with a TD while the aforementioned Marchiol had 56 rushing yards with a score and Cyncir Bowers had 54 rushing yards with a touchdown. Cam Vaughn led the Mountaineers with 7 catches for 126 yards and a touchdown in the win. On defense, Chase Wilson had a team-high 6 total tackles along with a sack while Reid Carrico had a sack and Hammond Russell IV had a pair of sacks and 2.5 TFLs.

Why the West Virginia Mountaineers will win

  • West Virginia has won eight of its last nine September games against non-AP-ranked teams.
  • The favorite has covered the spread in each of Ohio’s last four games at Peden Stadium.
  • Ohio has failed to cover the spread in three of its last four games against non-conference opponents.

Ohio Recap

The Ohio Bobcats come into this game looking to rebound from a 34-31 loss at the hands of Rutgers last time out to sit at 0-1 on the year. After this game, the Bobcats will head on the road for their big in-state rivalry game against Ohio State.

Bobcats Looking To Take Advantage of Home Spot

Parker Navarro threw for 239 yards and 3 TDs while also rushing for 93 yards and a touchdown. Sieh Bangura also rushed for 86 yards while Chase Hendricks led Ohio’s receiving group with 9 grabs for 115 yards while Jake Bruno had a pair of TD grabs and Mason Williams also had a touchdown reception of his own. On defense, Adonis Williams Jr. had a team-high 11 total tackles while Jay Crable added a sack for the Bobcats in the losing effort. 

Why the Ohio Bobcats will win

  • Ohio has won 17 of its last 18 games at Peden Stadium.
  • West Virginia has lost each of its last six road openers.
  • Ohio has covered the spread in seven of its last eight games.
  • West Virginia has failed to cover the spread in five of its last six road openers.

Total Points Facts

  • Eight of West Virginia’s last nine road games have gone OVER the total points line.
  • Each of Ohio’s last five home games in September have gone UNDER the total points line.

West Virginia Mountaineers vs. Ohio Bobcats Prediction

I’m going to lean towards Ohio here. I genuinely think that Ohio is live here with West Virginia having a prime look-ahead spot on deck with their matchup against Pitt forthcoming. Ohio battled Rutgers tough last week and I think at home, this Bobcats team is really dangerous. Give me Ohio and the points here.

Chris Ruffolo's Pick: Ohio +3

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