West Virginia vs Kansas Prediction 9/20/2025 Today’s College Football Picks

In this article, we will formulate a West Virginia vs Kansas Prediction for this College Football Week 4 game on Saturday, September 20th at the David Booth Kansas Memorial Stadium. Let’s take a look at the prediction for this College Football matchup.

Kansas Preview

Kansas has a 2-1 record this season and are coming off a 31-42 road defeat in Missouri. Offensively, the Jayhawks average 36.0 points per game, which ranks 48th in the nation. Defensively, they allow 18.7 points per game, which ranks 52nd in the nation. Kansas averages 422.7 total yards per game, with 174.3 rushing yards and 248.3 passing yards per game. They allow 318.0 total yards per game, 117.0 of them rushing and 201.0 passing yards per game.

Jalon Daniels leads the Jayhawks with 54/75 completed passes and 679 total passing yards. He also adds 90 rushing yards and 1 touchdown. Daniel Hishaw Jr. leads the team in rushing yards, with 169 and 1 touchdown, while Leshon Williams adds 52 rushing yards and 1 touchdown. Emmanuel Henderson has a team-high 12 caught passes for a team-high 183 receiving yards, and has 2 touchdowns. Cam Pickett has caught 10 passes for 124 yards, and 3 touchdowns.

Defensively, Trey Lathan has a team-high 25 total tackles, 11 of them solo. Lyrik Rawls adds 17 total tackles, 11 of them solo and 1 interception. Leroy Harris III leads the Jayhawks in sacks, with 3.5, while Lyrik Rawls and Devin Dye each have 1 interception.

West Virginia Preview

West Virginia has a 2-1 record this season and are coming off a 31-24 home victory over Pittsburgh. Offensively, they average 28.7 points per game, which ranks 75th in the nation. Defensively, they allow 14.7 points per game, which ranks 34th in the nation. West Virginia averages 436.3 total yards per game, with 213.0 rushing yards and 223.3 passing yards per game. They allow 300.3 total yards per game, 93.7 of them rushing and 206.7 passing yards per game.

Nicco Marchiol leads West Virginia with 51/71 completed passes and 594 total passing yards. He also adds 61 rushing yards and 1 touchdown. Tye Edwards leads the team in rushing yards, with 141 and 3 touchdowns, while Jahiem White adds 133 rushing yards and 3 touchdowns. Cam Vaughn has a team-high 12 caught passes for a team-high 203 receiving yards, and has 1 touchdown. Grayson Barnes has caught 9 passes for 97 yards, and 1 touchdown.

Defensively, Fred Perry has a team-high 21 total tackles, 13 of them solo, and 1 sack. Darrian Lewis adds 21 total tackles, 10 of them solo and 2 interceptions. Chase Wilson leads West Virginia in sacks, with 3, while Darrian Lewis has a team-high 2 interceptions.

West Virginia Mountaineers @ Kansas Jayhawks Betting Trends: Week 4

Why the Kansas Jayhawks will win

• The home team has won nine of Kansas’ last 10 games.
• West Virginia has lost seven of its last nine road games in September.
• Kansas has covered the spread in five of its last six games against conference opponents.
• West Virginia has failed to cover the spread in five of its last six games against teams from Kansas.
• Kansas has won the first quarter in each of its last four home games against conference opponents.
• Kansas has won the first half in four of its last five home games against conference opponents.

Why the West Virginia Mountaineers will win

• West Virginia has won each of its last four September games as an underdog against non-AP-ranked teams.
• Kansas has lost each of its last six games in September.
• Kansas has failed to cover the spread in each of its last six games in September.
• West Virginia has covered the spread in each of its last four September games as an underdog against non-AP-ranked teams.
• Kansas has lost the first half in 26 of its last 31 games against conference opponents at David Booth Kansas Memorial Stadium.

Total Points Facts

• Each of West Virginia’s last eight games against teams from Kansas have gone OVER the total points line.
• Each of Kansas’ last seven games in Kansas have gone UNDER the total points line.

Kansas Jayhawks Player Prop Facts

• Heading into Week 4, Cam Pickett ranks T1st amongst qualified players for catch rate (100.0%) this season.

West Virginia Mountaineers Player Prop Facts

• Heading into Week 4, Darrian Lewis leads the Big 12 Conference for interceptions (2) this season.

Matchup/League Facts

• Kansas ranks 3rd among FBS teams for Q1 points per game this season (16.3).
• Kansas ranks 8th among FBS teams for average point differential in first quarters this season (+12.0).
• West Virginia ranks T1st among FBS teams for red zone percentage this season (100.0).
• West Virginia ranks T12th among FBS teams for interceptions this season (4).

West Virginia vs Kansas Prediction

In their previous meeting last season, West Virginia won 32-28 at home, covering the spread, as the game went over the point total. West Virginia is 9-1 in their last 10 head-to-head meetings against Kansas, and have won their last 4 visits in Kansas. Kansas is 6-1-1 against the spread in their last 8 meetings, and their last 4 meetings have gone over the total.  

In this West Virginia vs Kansas Prediction, Kansas is coming as 11.5-point home favorites. Both teams are coming off opposite outcomes in their previous games, and Kansas being such a big favorite does not make much sense. West Virginia has been looking great this season, as they have the same record as Kansas, and are 2-1 against the spread. They play very good defense, and they outscore their opponents by 14 points this season. On top of that, they are dominating Kansas in their recent meetings both overall and at home, so I like them to keep this one close. Take West Virginia and the +10 points in your back pocket.