Virginia Tech vs Florida State Prediction 11/15/2025 Today’s College Football Picks

The Virginia Tech Hokies and the Florida State Seminoles meet in week 12 college football action from Hard Rock Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Virginia Tech Hokies vs. Florida State Seminoles prediction.

Virginia Tech Hokies Recap

The Virginia Tech Hokies come into this game looking to rebound from a 28-16 loss at the hands of Louisville last time out prior to last week’s bye week to sit at 3-6 this season. After this game, Virginia Tech will head home for a game against Miami.

Hokies Drop 3 Of Last 4

Kyron Drones has thrown for 1,592 yards, 15 touchdowns and 6 interceptions on 58.5% passing while also rushing for 499 yards and 8 TDs. Marcellous Hawkins has 576 rushing yards to lead the Hokies while Terion Stewart has 395 rushing yards. Ayden Greene leads the Hokies with 24 catches for 382 yards and 2 TDs while Donavon Greene has 274 receiving yards as well on the year. Kaleb Spencer leads Virginia Tech’s defense with 49 total tackles while Kemari Copeland has a team-high 4.5 sacks. As a unit, Virginia Tech’s defense has combined for 18 sacks and 4 interceptions.

Florida State Seminoles Recap

The Florida State Seminoles come into this game looking to bounce back from their 24-10 loss at the hands of the Clemson Tigers last time out to sit at 4-5 this season. After this game, Florida State will head on the road for a game against NC State.

Seminoles Drop 5 Of Last 6

Tommy Castellanos has thrown for 2,128 yards, 11 touchdowns and 6 interceptions on 60% passing while also rushing for 359 yards and 6 touchdowns this season. Gavin Sawchuk leads Florida State in rushing with 433 yards and 8 touchdowns while Ousmane Kromah has 310 rushing yards and Samuel Singleton Jr. has 286 rushing yards and 4 touchdowns as well this season. Duce Robinson leads FSU in receiving with 43 catches for 813 yards and 4 touchdowns while Micahi Danzy has 522 receiving yards and 2 TDs this season. On defense, Earl Little Jr. has 57 total tackles while also leading the Seminoles with 4 interceptions. Mandrell Desir has a team-high 4 sacks while Ashlynd Barker has 3.5 sacks and the Seminole defense as a unit has combined for 24 sacks and 10 interceptions so far this season. 

Virginia Tech Hokies @ Florida State Seminoles Betting Trends: Week 12

Why the Florida State Seminoles will win

• Florida State has won each of its last 11 November games as a favorite.
• Virginia Tech has lost each of its last five games against teams from Florida.
• Virginia Tech has failed to cover the spread in five of its last six games as an underdog.
• The favorite has covered the spread in four of Florida State’s last five games at Doak Campbell Stadium.
• Virginia Tech has lost the first half in three of its last four games against conference opponents.

Why the Virginia Tech Hokies will win

• Florida State has lost 10 of its last 11 games against conference opponents.
• Virginia Tech has won three of its last four games against non-AP-ranked teams.
• Florida State has failed to cover the spread in six of its last seven games against conference opponents.
• Virginia Tech has covered the spread in four of its last five games in Florida.
• Virginia Tech has won the first half in six of its last eight road games against conference opponents.
• Virginia Tech has won the first quarter in three of its last four games against conference opponents.

Total Points Facts

• Each of Virginia Tech’s last six games as an underdog have gone UNDER the total points line.
• Seven of Florida State’s last eight games against conference opponents at Doak Campbell Stadium have gone UNDER the total points line.

Florida State Seminoles Player Prop Facts

• Heading into Week 12, Micahi Danzy ranks 3rd amongst qualified players for Yards Per Reception (22.7) this season.

Virginia Tech Hokies Player Prop Facts

• Heading into Week 12, Cameron Seldon ranks T2nd amongst qualified players for catch rate (95.5%) this season.

Matchup/League Facts

• Florida State has recorded the largest margin of victory of any FBS team this season (74-points vs East Texas A&M on September 6, 2025).
• Florida State has recorded the largest margin of victory in a home game this season (74-points vs East Texas A&M on September 6, 2025).
• Virginia Tech ranks T134th among FBS teams for red zone percentage against this season (97.1).
• Virginia Tech ranks T121st among FBS teams for average point differential in fourth quarters this season (-3.4).

Virginia Tech Hokies vs. Florida State Seminoles Prediction

I’m leaning towards Virginia Tech and the points here. I know that it’s Florida State’s final home game of the season, so maybe we get the grand effort from FSU in their home finale. That being said, the Hokies have been competitive in recent games, and I think Florida State wins here but I think VA Tech covers. Give me the points with the Hokies.

Chris Ruffolo's Pick: Virginia Tech +14