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Vanderbilt vs Virginia Tech Prediction 9/6/2025 Today’s College Football Picks
Pick details
Vanderbilt (1-0) vs Virginia Tech (0-1)
September 6, 2025 at 07:30 PM EDT
The Line: Betting Odds: Virginia Tech -0.5 — Over/Under: +47.5
In this article, we will formulate a Vanderbilt vs Virginia Tech Prediction for this College Football Week 2 game on Saturday, September 6th at the Lane Stadium. Let’s take a look at the prediction for this College Football matchup.
Kyron Drones had 15/35 passes, a team-high 221 passing yards but also threw two interceptions. Marcellous Hawkins added a team-high 58 rushing yards, while Donavon Greene caught 3 passes for 94 yards. Defensively, Keli Lawson had nine total tackles, five of them solo, while Matt Johnson had one sack. Mansoor Delane had one interception returned for 22 yards.
Diego Pavia had 20/25 passes, a team-high 275 passing yards and three touchdowns. Sedrick Alexander added a team-high 83 rushing yards, while Eli Stowers caught 4 passes for 86 yards. Defensively, Langston Patterson had six total tackles, four of them solo, while BJ Diakite had one sack. Martel Hight had one interception returned for 16 yards.
In this Vanderbilt vs Virginia Tech Prediction, Virginia Tech is coming in as -1-point home favorites, with the total set at 47.5 points. Both teams are coming off opposite outcomes in their season openers, but the Commodores had the weakest opposition. Vanderbilt still looked great, winning by 42 points and holding their opponents into just 3, while Virginia Tech struggled on the offensive end, with just 11 points. The Hokies were 4-3 at home last season and 6-6 ATS, while the Commodores were 2-3 on the road, but a strong 8-4 ATS. Vanderbilt won VT last season, and I like them today as well in an almost pickem price. Take the Vanderbilt Commodores to win on the road in this one.
Virginia Tech Hokies Preview
The Hokies are coming off a 11-24 home defeat by South Carolina in their season opener. Virginia Tech outgained their opponents by 336-328 yards. They had 15/35 completed passes, 221 passing yards, 115 rushing yards, with turnovers being 2-0. The Hokies went 8-18 in third down efficiency and had 4-40 penalties.Kyron Drones had 15/35 passes, a team-high 221 passing yards but also threw two interceptions. Marcellous Hawkins added a team-high 58 rushing yards, while Donavon Greene caught 3 passes for 94 yards. Defensively, Keli Lawson had nine total tackles, five of them solo, while Matt Johnson had one sack. Mansoor Delane had one interception returned for 22 yards.
Vanderbilt Commodores Preview
The Commodores are coming off a 45-3 home victory over Charleston Southern in their season opener. Vanderbilt outgained their opponents by 481-135 yards. They had 21/28 completed passes, 280 passing yards, 201 rushing yards, with turnovers being 0-2. The Commodores went 6-9 in third down efficiency and had 7-60 penalties.Diego Pavia had 20/25 passes, a team-high 275 passing yards and three touchdowns. Sedrick Alexander added a team-high 83 rushing yards, while Eli Stowers caught 4 passes for 86 yards. Defensively, Langston Patterson had six total tackles, four of them solo, while BJ Diakite had one sack. Martel Hight had one interception returned for 16 yards.
Vanderbilt vs Virginia Tech Prediction
In their only previous meeting last season, Vanderbilt won 34-27 at home in overtime, covering the spread, as the game went over the point total. ÂIn this Vanderbilt vs Virginia Tech Prediction, Virginia Tech is coming in as -1-point home favorites, with the total set at 47.5 points. Both teams are coming off opposite outcomes in their season openers, but the Commodores had the weakest opposition. Vanderbilt still looked great, winning by 42 points and holding their opponents into just 3, while Virginia Tech struggled on the offensive end, with just 11 points. The Hokies were 4-3 at home last season and 6-6 ATS, while the Commodores were 2-3 on the road, but a strong 8-4 ATS. Vanderbilt won VT last season, and I like them today as well in an almost pickem price. Take the Vanderbilt Commodores to win on the road in this one.
