Sep 6, 2025; Corvallis, Oregon, USA; Fresno State Bulldogs running back Bryson Donelson (6) on the field during warmups before the game against the Oregon State Beavers at Reser Stadium. Mandatory Credit: Craig Strobeck-Imagn Images

Southern vs Fresno State Prediction 9/13/2025 Today’s College Football Picks

Pick details

Southern (1-2) vs Fresno State (2-1)

September 13, 2025 at 10:00 PM EDT

The Line: Betting Odds: Fresno State — Over/Under:

(Get latest betting odds)

The Southern Jaguars and Fresno State Bulldogs meet Saturday in college football action at Valley Children’s Stadium. Here’s a Southern vs Fresno State Prediction. This article will include a Southern vs Fresno State Pick.

Southern Jaguars Betting Preview

The Southern Jaguars beat Mississippi Valley State, lost to Alabama State, and they play Jackson State next. The Southern Jaguars have lost 3 of their last 4 games. Cam’Ron McCoy is completing 51.7 percent of his passes for 312 yards, 2 touchdowns, and 2 interceptions. Cam Jefferson and Darren Morris have combined for 178 receiving yards and 2 touchdowns, while Dupree Fuller has 6 receptions.

The Southern Jaguars ground game is averaging 217 yards per contest, and Trey Holly leads the way with 217 yards and 2 touchdowns. Defensively, Southern is allowing 30 points and 358 yards per game. Horacio Johnson leads the Southern Jaguars with 12 tackles, Ckelby Givens has 4 sacks and Elijah West has 4 pass deflections.

Fresno State Bulldogs Betting Preview

The Fresno State Bulldogs beat Georgia Southern and Oregon State, and they play Hawaii next. The Fresno State Bulldogs have split their last 10 games. E.J. Warner is completing 68.9 percent of his passes for 476 yards, 0 touchdowns, and 5 interceptions. Josiah Freeman and Ezekiel Avit have combined for 226 receiving yards on 20 catches, while Bryson Donelson has 6 receptions.

The Fresno State Bulldogs ground game is averaging 195 yards per contest, and Bryson Donelson leads the way with 235 yards and 1 touchdown. Defensively, Fresno State is allowing 24 points and 384.3 yards per game. Jadon Pearson leads the Fresno State Bulldogs with 34 tackles, Jayden Davis has 1 sack and Jakari Embry has 1 interception.

Southern Jaguars @ Fresno State Bulldogs Betting Trends: Week 3

Why the Fresno State Bulldogs will win

  • Fresno State has won nine of its last 10 home games in September.
  • Fresno State has covered the spread in each of its last three games in California.

Why the Southern Jaguars will win

  • Fresno State has failed to cover the spread in four of its last five home games against non-FBS teams.

Total Points Facts

  • Twelve of Fresno State’s last 16 September games at Valley Children’s Stadium have gone OVER the total points line.

Fresno State Bulldogs Player Prop Facts

  • Heading into Week 3, E.J. Warner has the most passing yards without a passing touchdown this season (476).

Matchup/League Facts

  • Fresno State ranks T7th among FBS teams for interceptions this season (3).
  • Fresno State ranks T11th among FBS teams for 1st downs this season (57).

Southern vs Fresno State Prediction

Fresno State has lit up the scoreboard in its last two games and has yet to record a passing touchdown. That’s probably good news, as it’s only a matter of time before the air game gets going. Southern has struggled against bad FCS teams, and that includes barely beating Mississippi Valley State. This is likely going to be an ugly game late Saturday night. I expect a big number, but I’ll lay it anyway, with Fresno State at home.

Randy Chambers's Pick: Fresno State ATS

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