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SMU vs Missouri State Prediction 9/13/2025 Today’s College Football Picks
Pick details
SMU (1-1) vs Missouri State (1-1)
September 13, 2025 at 03:30 PM EDT
The Line: Betting Odds: Missouri State +27.5 — Over/Under: 61.5
SMU and Missouri State meet Saturday in Week 3 college football action from the Robert W Plaster Stadium. Here’s an SMU vs Missouri State prediction. We will look at this from a betting perspective and determine the best SMU Mustangs vs Missouri State Bears pick. We will examine:
The SMU Mustangs’ recent form and player performance
The Missouri State Bears’ recent form and player performance
Recent betting trends and streaks involving the Bears’
Recent betting trends and streaks involving the Mustangs’
Recent betting trends in games played between SMU and Missouri State
A summary that ties it all together and produces a favorable betting outcome for the SMU vs Missouri State game.
SMU faced off against East Texas A&M in the first game of the season, and they were able to secure the 42-13 victory. In the last game against Baylor, they were competitive, but they ended up losing 48-45 in overtime. They scored 14 points in the 4th quarter, but in the second overtime period, it was missed field goal that ended up leading to the loss. They allowed Bayor quarterback Sawyer Robertson to complete 34 of his 50 passes for 440 yards and four touchdowns. Bryson Washington also rushed for 115 yards and two touchdowns against their defense. In this game, if SMU wants any chance to come away with a victory, the defense is going to need to be a whole lot better.
SMU quarterback Kevin Jennings completed 16 of his 22 passes for 295 yards, three touchdowns, and one interception. Romello Brinson was a star, catching four passes for 126 yards and two touchdowns. T.J. Harden had a huge game on the ground, rushing 19 times for 115 yards, and three touchdowns. In this game, SMU really needs the defense to be a whole lot better.
Why SMU Will Beat Missouri State
Missouri State in the first game of the season faced off against USC and and it was an ugly game. Missouri State scored only 13 points, while the defense gave up 73 points. Missouri State finished the game with 224 total yards while they allowed USC to gain 597 yards. In the last game against Marshall, Missouri State scored 21 points, and they ended up winning by one point. At halftime they were down 17-7, but in the second half they made the comeback, and that was the difference.
Under center for Missouri State is Jacob Clark and he completed 21 of his 31 passes for 359 yards, three touchdowns, and one interception. Ramone Green Jr finished with four catches, 123 yards and a touchdown. The defense was also really good against the pass, allowing Zion Turner to complete only 13 of his 24 passes for 83 yards, zero touchdowns, and one interception.
Why Missouri State Will Beat SMU
If you like scoring, make sure to tune into this game, because it’s going to be a shootout. Missouri State gave up 73 points in the first game against UCLA, and they are going to be awful again here. SMU’s offense is elite and they are going to air the ball out in this game. Outside of the turnovers for Jacob Clark, I have been impressed by him, and he’s going to have a huge game here. Will it be enough to win? Probably not. That being said, it will be enough to push this game over the total. Back the over.
The SMU Mustangs’ recent form and player performance
The Missouri State Bears’ recent form and player performance
Recent betting trends and streaks involving the Bears’
Recent betting trends and streaks involving the Mustangs’
Recent betting trends in games played between SMU and Missouri State
A summary that ties it all together and produces a favorable betting outcome for the SMU vs Missouri State game.
How Does SMU Bounce Back?
SMU faced off against East Texas A&M in the first game of the season, and they were able to secure the 42-13 victory. In the last game against Baylor, they were competitive, but they ended up losing 48-45 in overtime. They scored 14 points in the 4th quarter, but in the second overtime period, it was missed field goal that ended up leading to the loss. They allowed Bayor quarterback Sawyer Robertson to complete 34 of his 50 passes for 440 yards and four touchdowns. Bryson Washington also rushed for 115 yards and two touchdowns against their defense. In this game, if SMU wants any chance to come away with a victory, the defense is going to need to be a whole lot better.
SMU quarterback Kevin Jennings completed 16 of his 22 passes for 295 yards, three touchdowns, and one interception. Romello Brinson was a star, catching four passes for 126 yards and two touchdowns. T.J. Harden had a huge game on the ground, rushing 19 times for 115 yards, and three touchdowns. In this game, SMU really needs the defense to be a whole lot better.
Why SMU Will Beat Missouri State
- SMU has won each of its last five games against opponents from the Conference USA.
- SMU has covered the spread in three of its last four games after coming off overtime.
Which Missouri State Team Shows Up?
Missouri State in the first game of the season faced off against USC and and it was an ugly game. Missouri State scored only 13 points, while the defense gave up 73 points. Missouri State finished the game with 224 total yards while they allowed USC to gain 597 yards. In the last game against Marshall, Missouri State scored 21 points, and they ended up winning by one point. At halftime they were down 17-7, but in the second half they made the comeback, and that was the difference.
Under center for Missouri State is Jacob Clark and he completed 21 of his 31 passes for 359 yards, three touchdowns, and one interception. Ramone Green Jr finished with four catches, 123 yards and a touchdown. The defense was also really good against the pass, allowing Zion Turner to complete only 13 of his 24 passes for 83 yards, zero touchdowns, and one interception.
Why Missouri State Will Beat SMU
- SMU has lost three of its last four games.
- SMU has failed to cover the spread in four of its last five road openers.
SMU vs Missouri State Prediction
If you like scoring, make sure to tune into this game, because it’s going to be a shootout. Missouri State gave up 73 points in the first game against UCLA, and they are going to be awful again here. SMU’s offense is elite and they are going to air the ball out in this game. Outside of the turnovers for Jacob Clark, I have been impressed by him, and he’s going to have a huge game here. Will it be enough to win? Probably not. That being said, it will be enough to push this game over the total. Back the over.
