Oklahoma State vs Oregon Prediction 9/6/2025 Today’s College Football Picks

In this article we will formulate an Oklahoma State vs Oregon prediction for this College Football game on Saturday, September 6th at Autzen Stadium in Eugene, Oregon. Let’s take a look at the prediction for this week 2 matchup. 

Oklahoma State Cowboys Betting Preview

The Oklahoma State Cowboys are 1-0 this year after they defeated UT Martin by a score of 27-7 in their first game. Oklahoma State scored twice in the first quarter to lead 14-7 and they took a 17-7 lead into the half. The Cowboys only managed 10 points in the second half, but they still picked up a comfortable victory. Oklahoma State out gained UT Martin by a total of 359-225, went 10-18 on third down conversions, and won the turnover battle by a total of 1-0. Zane Flores went 13-20 for 136 yards in the game, while Hauss Hejny went 5-10 for 96 yards and one touchdown. Kalib Hicks carried the ball 21 times for 56 yards, while Terrill Davis caught two passes for 75 yards in the win. The Oklahoma State defense recorded four sacks and nine tackles for loss in the victory. 

Oklahoma State did get a 20-point win in their first game, but the offense wasn’t great and needs improvement. The Cowboys looked very good on defense, but the passing attack was just average and the lead running back averaged less than three yards per carry, which is not a recipe for success against Oregon. 

Oregon Ducks Betting Preview

The Oregon Ducks are 1-0 this season after they defeated Montana State by a score of 59-13 last week. Oregon scored 17 points in the first quarter and they led 38-3 at the half. The Ducks had their lead cut to 38-6 in the third, but they scored the next 21 points to put the game away. Oregon out gained Montana State by a total of 506-244, went 7-10 on third down conversions, and tied the turnover battle at one in the win. Dante Moore went 18-23 for 213 yards and three touchdowns, Noah Whittington carried the ball 10 times for 68 yards and one touchdown, while Malik Benson caught five passes for 51 yards and one score. The Oregon defense recorded three sacks and seven tackles for loss in the victory. 

Oregon had some question marks on the offensive side of the ball coming into last week, but Moore looked great under center and the offense flourished. If Moore can protect the football, which he has had trouble with in the past, this will be a very good Oregon team. 

Why Oregon will beat Oklahoma State

Oregon has won each of its last 32 games against non-AP-ranked teams.
Oklahoma State has lost nine of its last 10 games.
Oklahoma State has failed to cover the spread in nine of its last 10 games.
The favorite has covered the spread in five of Oklahoma State’s last six games.

Why Oklahoma State will beat Oregon

Oklahoma State has won 11 of its last 12 road openers.
The team ranked 6th in the AP Poll has failed to cover the spread in each of its last three games.
Oklahoma State has covered the spread in six of its last eight road games in September.

Total Points Facts

Five of Oregon’s last six September home games against non-AP-ranked teams have gone OVER the total points line.
Seven of Oklahoma State’s last nine games against non-conference opponents have gone UNDER the total points line.

Matchup/League Facts

Oregon ranks T1st among FBS teams for red zone percentage this season (100.0).
Oregon ranks T3rd among FBS teams for Q1 points per game this season (17.0).
Oklahoma State ranks T1st among FBS teams for Q4 opponent points per game this season (0.0).
Oklahoma State ranks T1st among FBS teams for H2 opponent points per game this season (0.0).

David Racey is 7-2 (77.8%) in his last nine College Football plays. Click here for his premium plays for today!

Oklahoma State vs Oregon Prediction 

Oregon comes into this matchup as a pretty big favorite to get the win and they will be at home. The Ducks looked great last week on both sides of the ball, while the Oklahoma State offense sputtered. The Cowboys need to make some huge improvements this week in order to keep this game close, especially in the running game. I do think Okie State will play better this week, but this Oregon offense is going to roll. I like this game to be high scoring and I wouldn’t be shocked if Oregon was up near the 50’s. Take the over here.