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Ohio vs Ohio State Prediction 9/13/2025 Today’s College Football Picks
Pick details
Ohio (1-1) vs Ohio State (2-0)
September 13, 2025 at 07:00 PM EDT
The Line: Betting Odds: Ohio State -30.5 — Over/Under: +51.5
Ohio and Ohio State meet Saturday in Week 3 college football action from Ohio Stadium. Here’s a Ohio vs Ohio State prediction. We will look at this from a betting perspective and determine the best Ohio Bobcats vs Ohio State Buckeyes pick. We will examine:
The Ohio Bobcats’ recent form and player performance
The Ohio State Buckeyes’’ recent form and player performance
Recent betting trends and streaks involving the Bobcats’
Recent betting trends and streaks involving the Buckeyes
Recent betting trends in games played between Ohio and Ohio State
A summary that ties it all together and produces a favorable betting outcome for the Ohio and Ohio State game.
It has been a strong start to the season for Ohio State, and they have a ton of confidence heading into this game. Ohio State faced off against Texas in the first game and they secured the 14-7 victory. Last Saturday, Ohio State faced off against Grambling, and they were able to secure the 70-0 victory. At the end of the first quarter they were up 21-0 and they never looked back on the way to the victory. Julian Sayin completed 18 of his 19 passes for 306 yards, four touchdowns, and one interception. Bo Jackson finished with nine carries for 108 yards and a touchdown. There were four different runners who put up 42 yards on the ground, and three of those found the end zone.
The defense was quite impressive, and they allowed only 166 total yards. We know this defense is elite, and this is another game where they are going to try and flex their muscles again. Ohio State will probably be disappointed with their performance if they give up more than a touchdown in this game.
Why Ohio State Will Beat Ohio
Ohio in the first game faced off against Rutgers and they ended up losing 34-31. They outscored Rutgers 14-3 in the second half, but they ended up falling just short. In the last game, Ohio faced off against West Virginia, and they were able to secure the 17-10 victory. Even though they won, and it was a great win, they need better quarterback play or this is going to be a long game. Parker Navarro completed 22 of his 31 passes for 247 yards and one touchdown. He also had three interceptions and that is the biggest issue.
If Ohio wants any chance to even be competitive in this game, they can’t be turning the ball over, or this game is going to get out of control early. Navarro did rush 18 carries for 87 yards. This game is going to comedown to Navarro and what he’s able to do at the quarterback position.
Why Ohio will Beat Ohio State
Ohio State is going to end up cruising to the victory here. Navarro didn’t play awful in the last game in terms of moving the ball, but three interceptions are a major issue, and it’s only going to get worse against the Ohio State defense. The Buckeyes are going to step in a major way here, and I don’t think the Buckeyes are going to even give a touchdown here. Julian Sayin is going to have another elite game under center, and Ohio’s defense is going to give up at least 50 points here. This game is going to get out of hand early, and Ohio State is going to end up winning in blowout fashion. Back Ohio State to cover the spread.
The Ohio Bobcats’ recent form and player performance
The Ohio State Buckeyes’’ recent form and player performance
Recent betting trends and streaks involving the Bobcats’
Recent betting trends and streaks involving the Buckeyes
Recent betting trends in games played between Ohio and Ohio State
A summary that ties it all together and produces a favorable betting outcome for the Ohio and Ohio State game.
Strong Start for Ohio State
It has been a strong start to the season for Ohio State, and they have a ton of confidence heading into this game. Ohio State faced off against Texas in the first game and they secured the 14-7 victory. Last Saturday, Ohio State faced off against Grambling, and they were able to secure the 70-0 victory. At the end of the first quarter they were up 21-0 and they never looked back on the way to the victory. Julian Sayin completed 18 of his 19 passes for 306 yards, four touchdowns, and one interception. Bo Jackson finished with nine carries for 108 yards and a touchdown. There were four different runners who put up 42 yards on the ground, and three of those found the end zone.
The defense was quite impressive, and they allowed only 166 total yards. We know this defense is elite, and this is another game where they are going to try and flex their muscles again. Ohio State will probably be disappointed with their performance if they give up more than a touchdown in this game.
Why Ohio State Will Beat Ohio
- Ohio State has won each of its last 24 September home games against non-AP-ranked teams.
- Ohio has lost each of its last five road games against opponents from the Big Ten Conference.
- Ohio State has covered the spread in seven of its last eight games.
- Ohio has failed to cover the spread in three of its last four road games against opponents from the Big Ten Conference.
- Ohio has lost the first half in each of its last four road games against opponents from the Big Ten Conference.
What a Start for Ohio
Ohio in the first game faced off against Rutgers and they ended up losing 34-31. They outscored Rutgers 14-3 in the second half, but they ended up falling just short. In the last game, Ohio faced off against West Virginia, and they were able to secure the 17-10 victory. Even though they won, and it was a great win, they need better quarterback play or this is going to be a long game. Parker Navarro completed 22 of his 31 passes for 247 yards and one touchdown. He also had three interceptions and that is the biggest issue.
If Ohio wants any chance to even be competitive in this game, they can’t be turning the ball over, or this game is going to get out of control early. Navarro did rush 18 carries for 87 yards. This game is going to comedown to Navarro and what he’s able to do at the quarterback position.
Why Ohio will Beat Ohio State
- Ohio has won 11 of its last 12 games in Ohio.
- Ohio has covered the spread in eight of its last nine games.
Ohio vs Ohio State Prediction
Ohio State is going to end up cruising to the victory here. Navarro didn’t play awful in the last game in terms of moving the ball, but three interceptions are a major issue, and it’s only going to get worse against the Ohio State defense. The Buckeyes are going to step in a major way here, and I don’t think the Buckeyes are going to even give a touchdown here. Julian Sayin is going to have another elite game under center, and Ohio’s defense is going to give up at least 50 points here. This game is going to get out of hand early, and Ohio State is going to end up winning in blowout fashion. Back Ohio State to cover the spread.
