Florida vs LSU Prediction 9/13/2025 Today’s College Football Picks

In this article we will formulate a Florida vs LSU prediction for this College Football game on Saturday, September 13th at Tiger Stadium in Baton Rouge, Louisiana. Let’s take a look at the prediction for this week 3 matchup. 

Florida Gators Betting Preview

The Florida Gators are 1-1 (0-0) this season after they lost to South Florida by a score of 18-16 in their last game. Florida led 3-0 after the first quarter and it was a field goal fest in the second, as they led 9-6 at halftime. The Gators fell behind in the third, but they rallied to lead 16-15 in the fourth, before allowing the winning field goal as time expired. Florida was out gained by a total of 391-355, went 4-12 on third down conversions, and lost the turnover battle by a margin of 1-0. DJ Lagway went 23-33 for 222 yards, one touchdown, and one interception, while Jadan Baugh rushed 18 times for 93 yards in the game. Eugene Wilson III led the receivers with seven catches for 60 yards and one score. 

Florida defeated LIU by a score of 55-0 to open the season in week one. The Gators are averaging 38.5 points per game with 236.5 passing yards and 166.5 rushing yards per game this year, while the defense has allowed 9.0 points against per game. DJ Lagway has completed 74.5% of his passes for 342 yards, four touchdowns, and one interception, while Vernell Brown III has caught eight passes for 135 yards this year. Jadan Baugh has been the leading rusher with 197 yards and one score on 27 carries. 

LSU Tigers Betting Preview

The LSU Tigers are 2-0 (0-0) this year after they defeated Louisiana Tech by a score of 23-7 last week. LSU led 7-0 after the first quarter, but they only led 10-0 at the half. The Tigers did have their lead cut to 20-7 in the fourth, but they added a field goal to seal the victory. LSU out gained La Tech by a total of 365-154, went 9-16 on third down conversions, and lost the turnover battle by a total of 1-0. Garrett Nussmeier went 26-41 for 237 yards, one touchdown, and one interception, while Harlem Berry rushed six times for 56 yards in the win. Barion Brown caught eight passes for 94 yards to lead the LSU receivers in the game. 

LSU opened the season with a huge win over Clemson on the road by a score of 17-10. The Tigers are averaging 20 points per game with 242.5 passing yards and 118 rushing yards per game, while the defense has allowed 8.5 points against per game this season. Garrett Nussmeier has completed 68.4% of his passes for 469 yards, two touchdowns, and one interception, while Aaron Anderson has caught 14 passes for 172 yards this year. LSU’s ground game has been led by Caden Durham, who has rushed 30 times for 103 yards and two scores this season. 

Why LSU will beat Florida 

LSU has won each of its last 11 September games at Tiger Stadium.
Florida has lost each of its last eight games against top-5 AP-ranked teams.
LSU has covered the spread in three of its last four games.
Florida has failed to cover the spread in three of its last four games against top-5 AP-ranked teams.

Why Florida will beat LSU

Florida has won five of its last six games.
LSU has failed to cover the spread in seven of its last eight September games as a favorite.
Florida has covered the spread in each of its last four September games against top-15 AP-ranked teams.

Total Points Facts

Each of Florida’s last six road games in September have gone OVER the total points line.
Six of LSU’s last seven games at Tiger Stadium have gone UNDER the total points line.

Matchup/League Facts

LSU ranks T5th among FBS teams for red zone percentage against this season (50.0).
LSU ranks 7th among FBS teams for rushing yards allowed per game this season (44.5).
Florida ranks T14th among FBS teams for H1 opponent points per game this season (3.0).
Florida ranks T14th among FBS teams for average point differential in second quarters this season (+12.0).

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Florida vs LSU Prediction 

Florida comes into this contest after a terrible loss to South Florida last week, and they will be on the road for this big game. The Gators will try to bounce back here, but it won’t be easy in one of toughest places to play in the country. LSU didn’t play well in their last game against La Tech, but it was a trap game between Clemson and Florida. I really like both quarterbacks in this game and even though the defenses have been tough, I think we will see some scoring. Take the over in this matchup.