Delaware vs Colorado Prediction 9/6/2025 Today’s College Football Picks

In this article, we will formulate a Delaware vs Colorado Prediction for this College Football Week 2 game on Saturday, September 6th at the Folsom Field. Let’s take a look at the prediction for this College Football matchup.

Colorado Buffaloes Preview

The Buffaloes are coming off a 20-27 home defeat by Georgia Tech in their season opener. Colorado got outgained by their opponents by 463-305 yards. They had 17/29 completed passes, 159 passing yards, 146 rushing yards, with turnovers being 0-3. The Buffaloes went 6-13 in third down efficiency and had 7-70 penalties.

Kaidon Salter had 17/28 passes, a team-high 159 passing yards and one touchdown. Micah Welch added a team-high 64 rushing yards, while Omarion Miller caught 1 pass for 39 yards. Defensively, Reginald Hughes had nine total tackles, six of them solo, while Quency Wiggins and Arden Walker had one sack each. The Buffaloes did not have any interceptions in this game.

Delaware Blue Hens Preview

The Blue Hens are coming off a 35-17 home victory over Delaware State in their season opener. Delaware outgained their opponents by 409-349 yards. They had 31/44 completed passes, 272 passing yards, 137 rushing yards, with turnovers being 1-2. The Blue Hens went 8-13 in third down efficiency and had 6-55 penalties.

Nick Minicucci had 28/36 passes, a team-high 251 passing yards and three touchdowns. Jo Silver added a team-high 44 rushing yards, while Jake Thaw caught 7 passes for 92 yards. Defensively, Gavin Moul had ten total tackles, four of them solo, while Jack Hall and KT Seay had one sack each. The Blue Hens did not have any interceptions in this game.

Why the Colorado Buffaloes will win

• The favorite has won each of Colorado’s last nine games at Folsom Field.
• Colorado has covered the spread in each of its last five games as a favorite in Colorado.

Why the Delaware Blue Hens will win

• Colorado has lost three of its last four games.
• Colorado has failed to cover the spread in six of its last seven games against non-conference opponents at Folsom Field.
• Colorado has lost the first half in five of its last six home games against non-conference opponents.

Total Points Facts

• Each of Colorado’s last four games have gone UNDER the total points line.

Matchup/League Facts

• Colorado ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
• One of Colorado’s one games this season have been decided by a margin of seven points or less – equal-most amongst FBS teams.
• Delaware ranks T1st among FBS teams for Q1 opponent points per game this season (0.0).
• Delaware ranks T1st among FBS teams for 4th down conversion percentage this season (100.0).

Delaware vs Colorado Prediction

This will be the first meeting between those two teams.

In this Delaware vs Colorado Prediction, Colorado is coming in as -23.5-point home favorites, with the total set at 58.5 points. Both teams are coming off opposite outcomes in their season openers, but the opposition was completely different. The Blue Hens won an inferior team at home, but I don’t trust them on the road in this spot. The Buffaloes are looking for their first win of the season, and playing their first home game of the season is the perfect opportunity. Take the Colorado Buffaloes and lay the points at home.