Michigan State's Aidan Chiles runs for a gain against Western Michigan during the second quarter on Friday, Aug. 29, 2025, in East Lansing.

Boston College vs Michigan State Prediction 9/6/2025 Today’s College Football Picks

Pick details

Boston College (1-0) vs Michigan State (1-0)

September 6, 2025 at 07:30 PM EDT

The Line: Betting Odds: Michigan State -3 — Over/Under: +46.5

(Get latest betting odds)

The Boston College Eagles and the Michigan State Spartans meet in week 2 college football action from Spartan Stadium on Saturday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Boston College Eagles vs. Michigan State Spartans prediction.

Boston College Eagles Recap

The Boston College Eagles come into this game looking to add on to their 66-10 beatdown win over Fordham to start the year with a 1-0 record. After this game, the Eagles will head on the road for their ACC opener against Stanford. 

Eagles Looking To Build On Rout

Dylan Lonergan threw for 268 yards and 4 touchdowns on 26 of 34 passing while Grayson James went 5 for 5 with a touchdown and 190 passing yards. Turbo Richard had a team-high 48 rushing yards and a touchdown, while Bo MacCormack III and Alex Broome each had a rushing score as well in the win. Lewis Bond led BC’s receiving group with 11 grabs for 138 yards while Dawson Pough had 3 receptions for 96 yards and a touchdown. Jaedn Skeete added a pair of receiving TDs while Reed Harris and Jordan McDonald each had a touchdown as well for Boston College. On defense, Daveon Crouch added 6 total tackles including 5 solo tackles and a sack while KP Price added 5 solo tackles and Carter Davis and Micah Amedee each had a sack as well. Crouch also chipped in a 28-yard pick-six to get in on the scoring as well for the Eagles.

Why the Boston College Eagles will win

  • Boston College has won each of its last four September games against non-AP-ranked teams.
  • Michigan State has lost three of its last four home games in September.
  • Michigan State has failed to cover the spread in each of its last six games.
  • Boston College has covered the spread in six of its last seven games.

Michigan State Recap

The Michigan State Spartans come into this game looking to add on to their 23-6 win over the Western Michigan Broncos last time out to improve to 1-0 on the year. After this game, the Spartans will welcome Youngstown State to town for a matchup.

Spartans Looking For Another Strong Showing To Start The Year

Aidan Chiles threw for 155 yards and a touchdown on 17 of 23 passing while Makhi Frazier had 103 rushing yards and a touchdown and Brandon Tullis added 52 rushing yards with a score as well. Omari Kelly led the Spartans in receiving with 7 grabs for 75 yards while Nick Marsh added 5 catches for 32 yards and a touchdown. On defense, Jordan Hall added 8 total tackles with a sack while Malik Spencer, Jalen Thompson and Anelu Lafaele each had a sack and Wayne Matthews III added an interception as well. 

Why the Michigan State Spartans will win

  • Michigan State has won each of its last nine September games as a favorite.
  • Boston College has lost four of its last five road games in September.
  • Boston College has failed to cover the spread in 10 of its last 11 September games against non-AP-ranked teams.
  • Michigan State has covered the spread in four of its last five September games as a favorite.

Total Points Facts

  • Nine of Michigan State’s last 10 home games in September have gone UNDER the total points line.
  • Seven of Boston College’s last eight games have gone OVER the total points line.

Boston College Eagles vs. Michigan State Spartans Prediction

I’m siding with the under here. These are two teams that I’m not really fond of from an offensive perspective and this just feels like the kind of game that’s going to be a slog for a full 60 minutes, kind of a first to 20 wins kind of game if we even get that high. Give me the under.

Chris Ruffolo's Pick: Under 46.5

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