Seattle Seahawks vs Carolina Panthers Prediction 12/28/2025 Today’s NFL Picks

In this article, we will formulate a Seahawks vs Panthers Prediction for this NFL Week 17 game on Sunday, December 28th. Let’s take a look at the prediction for this NFL matchup.

Carolina Panthers Preview

The Carolina Panthers have an 8-7 record this season and are sitting first in the NFC South. They are 9-6 ATS, 7-8 in Over/Under and have a 5-2 home record and a 3-5 away record. The Panthers are coming off a 23-20 home win against the Tampa Bay Buccaneers and will face the Buccaneers next.

Offensively, the Panthers average 19.1 points per game, ranking 27th in the NFL, while defensively, they allow 22.5 points per game, which is 14th. Carolina averages 306.7 total yards per game (182.8 passing and 123.9 rushing), while allowing 329.1 total yards per game (119.5 rushing and 209.6 passing).

Bryce Young leads the Panthers with 2691 passing yards with 63.5% completed passes and 21 touchdowns. Rico Dowdle leads the team in rushing yards with 1007, while Tetairoa McMillan has a team-high 65 receptions for 924 receiving yards, and seven touchdowns. Defensively, Christian Rozeboom has a team-high 105 total tackles (49 of them solo), while Derrick Brown leads the team in sacks, with 5, while Jaycee Horn has a team-high 5 interceptions.

Seattle Seahawks Preview

The Seattle Seahawks have a 12-3 record this season and are sitting first in the NFC West. They are 10-5 ATS, 9-6 in Over/Under and have a 6-2 home record and a 6-1 away record. The Seahawks are coming off a 38-37 home win against the Los Angeles Rams and will face the 49ers next.

Offensively, the Seahawks average 29.5 points per game, ranking 3rd in the NFL, while defensively, they allow 18.6 points per game, which is 2nd. Seattle averages 354.9 total yards per game (238.1 passing and 116.9 rushing), while allowing 303.2 total yards per game (94.1 rushing and 209.1 passing).

Sam Darnold leads the Seahawks with 3703 passing yards with 67.2% completed passes and 24 touchdowns. Kenneth Walker III leads the team in rushing yards with 879, while Jaxon Smith-Njigba has a team-high 104 receptions for 1637 receiving yards, and 10 touchdowns. Defensively, Ernest Jones has a team-high 116 total tackles (57 of them solo), while Byron Murphy and Leonard Williams each lead the team in sacks, with 7 each, while Ernest Jones has a team-high 5 interceptions.

Seattle Seahawks @ Carolina Panthers Betting Trends: Week 17

Why the Carolina Panthers will win

• The underdogs have won eight of the Panthers’ last nine games at Bank of America Stadium.
• The Seahawks have lost each of their last four games following a Division win.
• The Seahawks have failed to cover the spread in each of their last eight games as favorites following a Division game.
• The Panthers have covered the spread in each of their last six December games as home underdogs.
• The Seahawks have lost the first half in 12 of their last 15 games in December.
• The Panthers have won the first quarter in three of their last four games as home underdogs against NFC West opponents.

Why the Seattle Seahawks will win

• The Seahawks have won each of their last 13 games as road favorites.
• The Panthers have lost each of their last six Week 17 games.
• The Panthers have failed to cover the spread in each of their last six Week 17 games.
• The Seahawks have covered the spread in seven of their last eight road games following a Division game.
• The Panthers have lost the first half in each of their last eight home games against teams that held a winning record.
• The Seahawks have scored the first touchdown in eight of their last nine games as favorites against NFC opponents.
• The Seahawks have won the first quarter in four of their last five Week 17 games.

Total Points Facts

• Each of the last eight games between the Seahawks and Panthers have gone OVER the total points line.
• Each of the Seahawks’ last six games as favorites against the Panthers have gone OVER the total points line.
• Eleven of the last 14 Sunday games at Bank of America Stadium have gone OVER the total points line.

Carolina Panthers Player Prop Facts

• Tetairoa McMillan has scored at least one touchdown in each of the Panthers’ last four games as underdogs.
• Chuba Hubbard has recorded 43+ rushing yards in 10 of his last 11 December appearances with the Panthers as underdogs.
• Andy Dalton has recorded 331+ passing yards in three of his last four appearances against the Seahawks.
• David Moore has recorded 11+ receiving yards in each of his eight previous December appearances with his team as an underdog against NFC opponents.
• Chuba Hubbard has recorded 60+ rushing and receiving yards in each of the Panthers’ last four home games as heavy underdogs (>+7.0 points).
• Tetairoa McMillan has scored the last touchdown in three of the Panthers’ last four games as underdogs.
• Andy Dalton has recorded 26+ completions in four of his last five appearances with his team as an underdog against NFC West opponents.
• Heading into Week 17, Jaycee Horn has recorded the equal-most interceptions in a single game this season (2 vs Jets, Week 7).

Seattle Seahawks Player Prop Facts

• Cooper Kupp has scored at least one touchdown in nine of his last 10 appearances on the East Coast.
• Sam Darnold has recorded 20+ completions in each of his last eight December appearances.
• Sam Darnold has recorded 240+ passing yards in each of his last 11 appearances with his team as a road favorite.
• Zach Charbonnet has recorded 44+ rushing yards in each of the Seahawks’ last four December road games against NFC opponents.
• Jaxon Smith-Njigba has recorded 92+ receiving yards in each of the Seahawks’ last six Sunday road games.
• Cooper Kupp has recorded 35+ rushing and receiving yards in 16 of his 18 previous appearances against NFC South opponents.
• Heading into Week 17, Jaxon Smith-Njigba ranks 1st in the NFL in receiving yards (1637) this season.

Matchup/League Facts

• Panthers – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 17.
• Heading into Week 17, the Panthers are the only team to overturn multiple 12+ point 2nd quarter deficits to win this season.
• Seahawks – six different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 17.
• Seahawks – two different players have recorded 80+ rushing yards in a game this season – equal-most in the NFL, heading into Week 17.

Seahawks vs Panthers Prediction

In this Seahawks vs Panthers Prediction, the Seahawks are coming as -7-point road favorites. The Seahawks have a better overall record and have been  almost perfect on the road, having more road wins than the Panthers have at home. They have been red-hot lately, with a 9-1 record in their last 10 games and 6-3 against the spread in their last 9, while the Panthers have been up and down lately, as their offense is struggling to find a rhythm. Seattle is a top-3 squad both offensively and defensibly this season, with a +10.9 point differential and are going up against the league’s fourth-worst offense in Carolina. Take the Seahawks and lay the points on the road in this one.

Nikos Lagouretos's Pick: Seattle Seahawks -7