Tennessee Titans running back Tony Pollard (20) runs the ball during the fourth quarter against the Kansas City Chiefs at Nissan Stadium in Nashville, Tenn., Sunday, Dec. 21, 2025.
Denny Simmons / The Tennessean / USA TODAY NETWORK via Imagn Images

New Orleans Saints vs Tennessee Titans Prediction 12/28/2025 Today’s NFL Picks

Pick details

MATCHUP New Orleans Saints Tennessee Titans
Team Records 5-10 3-12
Spread -2.5 -115 +2.5 -105
Moneyline -142 +120
Total Over 39.5 (-110) Under 39.5 (-110)
Where Nissan Stadium, Nashville, TN
When Sunday, December 28, 2025
Time 01:00 PM EST
TV CBS

The New Orleans Saints and Tennessee Titans meet Sunday in NFL action at Nissan Stadium. Here’s a New Orleans Saints vs Tennessee Titans Prediction. This article will include a New Orleans Saints vs Tennessee Titans Pick.

New Orleans Saints Betting Preview


The New Orleans Saints beat the Panthers and Jets, and they play the Falcons next. The New Orleans Saints have won 3 straight games. Tyler Shough is completing 66.5 percent of his passes for 1,792 yards, 7 touchdowns, and 5 interceptions. Juwan Johnson and Chris Olave have combined for 1,777 receiving yards and 11 touchdowns, while Rashid Shaheed has 44 receptions.

The New Orleans Saints ground game is averaging 92.8 yards per contest, and Alvin Kamara leads the way with 471 yards and 1 touchdown. Defensively, New Orleans is allowing 22.5 points and 303.5 yards per game. Demario Davis leads the New Orleans Saints with 131 tackles, Cameron Jordan has 8.5 sacks and Kool-Aid McKinstry has 3 interceptions.

Tennessee Titans Betting Preview


The Tennessee Titans lost to the 49ers, beat the Chiefs, and they play the Jaguars next. The Tennessee Titans have lost 8 of their last 10 games. Cam Ward is completing 60.2 percent of his passes for 2,866 yards, 13 touchdowns, and 7 interceptions. Chig Okonkwo and Elic Ayomanor have combined for 931 receiving yards and 4 touchdowns, while Gunnar Helm has 43 receptions.

The Tennessee Titans ground game is averaging 93.6 yards per contest, and Tony Pollard leads the way with 949 yards and 5 touchdowns. Defensively, Tennessee is allowing 26.9 points and 341.7 yards per game. Cedric Gray leads the Tennessee Titans with 144 tackles, Jeffery Simmons has 9 sacks and Cody Barton has 3 interceptions.

Why the Tennessee Titans will win

  • The Saints have lost each of their last five games as favorites without Juwan Johnson.
  • The underdogs have won four of the Saints’ last six games.
  • The Saints have failed to cover the spread in eight of their last nine Sunday games as road favorites.
  • The Titans have covered the spread in four of their last five home games.
  • The Saints have lost the first quarter in four of their last five Sunday games against teams that held a losing record.
  • The Saints have lost the first half in six of their last seven road games.

Why the New Orleans Saints will win

  • The Titans have lost each of their last 11 Sunday games against opponents on a winning streak.
  • The Saints have won each of their last four December road games against AFC opponents.
  • The Titans have failed to cover the spread in each of their last nine games as underdogs following a win.
  • The Saints have covered the spread in each of their last four Sunday games.
  • The road team has won the first quarter in each of the Saints’ last three Week 17 games.
  • The Titans have lost the first half in each of their last four games following a win.

Total Points Facts

  • Each of the Saints’ last six games following a win have gone UNDER the total points line.
  • Seven of the Titans’ last eight home games following a win have gone UNDER the total points line.

Tennessee Titans Player Prop Facts

  • Chimere Dike has scored a touchdown in each of the Titans’ last two games as underdogs against teams that held a losing record.
  • Cam Ward has recorded 21+ completions in each of the Titans’ last four games at Nissan Stadium.
  • Tyjae Spears has recorded 18+ receiving yards in each of his last seven appearances at Nissan Stadium.
  • Cam Ward has recorded 194+ passing yards in three of the Titans’ last four games at Nissan Stadium.
  • Tyjae Spears has recorded 27+ rushing yards in each of the Titans’ last six games at Nissan Stadium as slight underdogs (<+3.5 points).
  • Chigoziem Okonkwo has recorded 29+ rushing and receiving yards in each of the Titans’ last four games at Nissan Stadium.
  • Heading into Week 17, Tyjae Spears ranks 1st amongst qualified players for catch rate (90.2%) this season.

New Orleans Saints Player Prop Facts

  • Taysom Hill has scored a touchdown in five of his last six Week 17 appearances.
  • Juwan Johnson has recorded 46+ receiving yards in three of the Saints’ last four games as favorites.
  • Taysom Hill has recorded 44+ rushing and receiving yards in each of the Saints’ last four games as road favorites against AFC opponents.
  • Spencer Rattler has recorded 20+ rushing yards in each of his last three appearances against AFC opponents.
  • Heading into Week 17, Pete Werner ranks T1st in the league for fumbles recovered (3) this season.

Matchup/League Facts

  • Heading into Week 17, the Titans rank 32nd in the NFL in 3rd down percentage (32.0%) this season.
  • Heading into Week 17, the Titans rank 32nd in the NFL in 4th down percentage against (75.0%) this season.
  • Heading into Week 17, the Saints rank 32nd in the NFL in Q1 points per game (1.9) this season.
  • Heading into Week 17, the Saints rank 1st in the NFL in Q4 opponent points per game (3.3) this season.

New Orleans Saints vs Tennessee Titans Prediction


Don’t look now, but the Saints have won 3 straight games and appear eager to finish the season strong. The Titans continue to lose and don’t provide much optimism, being below average on both sides of the ball. The Titans haven’t won two straight games since November 2022. The Saints have covered 5 of their last 6 games, and they’re 2-1 SU and ATS this season as a favorite. I’ll lay the small number with the Saints, who have finally found life in their season.

Randy Chambers's Pick: New Orleans Saints -2.5

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