Oct 12, 2025; New Orleans, Louisiana, USA; New England Patriots quarterback Drake Maye (10) throws downfield during the second half against the New Orleans Saints at Caesars Superdome. Mandatory Credit: Matthew Hinton-Imagn Images
Matthew Hinton-Imagn Images

New England Patriots vs Tennessee Titans Prediction 10/19/2025 Today’s NFL Picks

Pick details

MATCHUP New England Patriots Tennessee Titans
Team Records 5-2 1-6
Where Nissan Stadium, Nashville, TN
When Sunday, October 19, 2025
Time 01:00 PM EDT
TV CBS

The New England Patriots and the Tennessee Titans meet in week 7 NFL action from Nissan Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a New England Patriots vs. Tennessee Titans prediction.

New England Patriots Recap

The New England Patriots come into this game looking to build on a 25-19 win over New Orleans last time out to sit at 4-2 this season. After this game, the Patriots will head home for a game against the Cleveland Browns.

Patriots Win 3 In A Row

Drake Maye has thrown for 1,522 yards, 10 touchdowns and 2 interceptions on 73.2% passing while Rhamondre Stevenson leads New England in rushing with 157 yards and 2 touchdowns. TreVeyon Henderson has 148 rushing yards and a touchdown while Stefon Diggs has a team-high 32 catches for 387 yards to lead New England’s receiving group. Kayshon Boutte has 301 receiving yards and 3 touchdowns while Hunter Henry has 277 receiving yards and 3 TDs. Three more Patriots have 100+ receiving yards as well on the year. On defense, Robert Spillane has a team-high 51 total tackles including 29 solo tackles while Harold Landry III has a team-high 4.5 sacks. As a unit, New England’s defense has combined for 13 sacks and 4 interceptions so far this season.

Tennessee Titans Recap

The Tennessee Titans come into this game looking to bounce back from their 20-10 loss at the hands of the Las Vegas Raiders last time out to sit at 1-5 this season. After this game, the Titans will head on the road for a game against the Indianapolis Colts.

Titans Looking To Rebound

Cam Ward has thrown for 1,101 yards, 3 touchdowns and 4 interceptions on 55% passing while Tony Pollard has 362 rushing yards to lead the Titans in rushing. Calvin Ridley has a team-high 290 receiving yards while Chig Okonkwo has a team-high 23 grabs for 218 yards and Elic Ayomanor has 196 receiving yards and 2 touchdowns. Gunnar Helm also has 113 receiving yards as well this season. On defense, Cedric Gray has a team-high 60 total tackles including 30 solo tackles while Jeffery Simmons has a team-high 4.5 sacks. As a unit, Tennessee’s defense has combined for 9 sacks and 4 interceptions so far this season.

New England Patriots @ Tennessee Titans Betting Trends: Week 7

Why the Tennessee Titans will win

  • The Titans have won each of their last six home games against AFC East opponents on a winning streak.
  • The Patriots have lost four of their last five games as road favorites against AFC South opponents.
  • The Patriots have failed to cover the spread in eight of their last nine games as road favorites against AFC South opponents.
  • The Titans have covered the spread in five of their last six October games at Nissan Stadium.
  • The Titans have won the first quarter in four of their last five games as home underdogs against AFC opponents.
  • The Patriots have lost the first half in seven of their last eight games as road favorites against AFC South opponents.
  • The Titans have scored the first touchdown in each of their last five home games against AFC East opponents.

Why the New England Patriots will win

  • The Titans have lost each of their last nine games against AFC opponents.
  • The Patriots have won each of their last 14 October games as road favorites.
  • The Titans have failed to cover the spread in each of their last 10 home games.
  • The Patriots have covered the spread in each of their last four road games.
  • The Patriots have scored the first touchdown in four of their last five games as favorites against AFC South opponents.
  • The Patriots have won the first quarter in 15 of their last 16 Week 7 games against AFC opponents.
  • The Titans have lost the first half in each of their last eight games against AFC opponents.

Total Points Facts

  • Each of the Patriots’ last six games as road favorites have gone UNDER the total points line.
  • Each of the Titans’ last four October games against AFC East opponents have gone OVER the total points line.
  • Three of the last four Sunday games at Nissan Stadium have gone OVER the total points line.

Tennessee Titans Player Prop Facts

  • Tony Pollard has scored a touchdown in three of his last four appearances with his team as a home underdog against AFC opponents.
  • Cam Ward has recorded 219+ passing yards in three of the Titans’ last four games.
  • Cam Ward has recorded 19+ completions in four of the Titans’ last five games.
  • Tyjae Spears has recorded 20+ rushing yards in nine of his last 10 appearances against AFC opponents.
  • Chigoziem Okonkwo has recorded 27+ receiving yards in each of the Titans’ last six games as moderate underdogs (+3.5 to +7.0 points).
  • Chigoziem Okonkwo has recorded 35+ rushing and receiving yards in each of the Titans’ last five games as moderate underdogs (+3.5 to +7.0 points).
  • Heading into Week 7, Chimere Dike ranks 1st in the NFL in kick return yards (732) this season.

New England Patriots Player Prop Facts

  • Hunter Henry has scored a touchdown in each of his three previous appearances with his team as a road favorite against AFC South opponents.
  • Drake Maye has recorded 261+ passing yards in each of the Patriots’ last five games following a win.
  • Drake Maye has recorded 26+ rushing yards in four of the Patriots’ last five road games against AFC opponents.
  • Drake Maye has recorded 22+ completions in five of the Patriots’ last six games following a win.
  • Demario Douglas has recorded 12+ receiving yards in each of his 10 previous October appearances.
  • Demario Douglas has recorded 14+ rushing and receiving yards in nine of his 10 previous October appearances.
  • Heading into Week 7, Drake Maye has the equal-most games with a 100+ passer rating this season (5).

Matchup/League Facts

  • Heading into Week 7, the Titans rank 32nd in the NFL in yards per game (232.3) this season.
  • Heading into Week 7, the Titans rank 32nd in the NFL in 3rd down percentage (28.0%) this season.
  • Patriots – five different players have recorded 70+ receiving yards in a game this season – most in the NFL, heading into Week 7.
  • Patriots – four different players have recorded 80+ receiving yards in a game this season – equal-most in the NFL, heading into Week 7.

New England Patriots vs. Tennessee Titans Prediction

I’m on the Patriots here. The Titans made a coaching change, and sometimes that can inspire change and inspire a rush of adrenaline to come out and give a strong performance. However, that coaching change doesn’t change the personnel on the field and there have been a lot of moments on the field where Cam Ward’s youth and the Titans’ youth as a whole that continue to hold them back and plague them and stop them from achieving their potential. I think New England is still the better team here and I think New England gets the job done in this one.

Chris Ruffolo's Pick: New England -7

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