Minnesota Vikings vs New York Giants Prediction 12/21/2025 Today’s NFL Picks

The Minnesota Vikings and the New York Giants meet in week 16 NFL action from MetLife Stadium on Sunday. We will look at this from a betting perspective and determine the best bets for this game. Here’s a Minnesota Vikings vs. New York Giants prediction.

Minnesota Vikings Recap

The Minnesota Vikings come into this game looking to add on to their 34-26 win over Dallas last time out to sit at 6-8 this season. After this game, Minnesota will head home for a game against Detroit. 

Minnesota Wins Back-To-Back Games

JJ McCarthy has thrown for 1,342 yards, 11 touchdowns and 11 INTs on 56.8% passing while Carson Wentz has thrown for 1,216 yards, 6 touchdowns and 5 picks on 65.1% passing. Jordan Mason has rushed for a team-high 659 yards and 6 touchdowns while Aaron Jones Sr. has 410 rushing yards as well on the year. Justin Jefferson leads Minnesota in receiving with 66 grabs for 832 yards and 2 TDs while Jordan Addison has 576 receiving yards and 3 TDs along with 39 catches and TJ Hockenson has 436 receiving yards and 50 catches and 3 TDs. Jalen Nailor has 395 receiving yards and 4 TDs as well this season. On defense, Blake Cashman leads the Vikings with 104 total tackles while Eric Wilson has 98 total tackles with 5.5 sacks. Dallas Turner also has 5.5 sacks and Minnesota’s defense as a whole has combined for 35 sacks and 5 interceptions so far this season.

New York Giants Recap

The New York Giants come into this game looking to shake off a 29-21 loss at the hands of Washington last time out to sit at 2-12 this season. After this game, the Giants will head on the road for a game against the Las Vegas Raiders.

Giants Lose 8 In A Row

Jaxson Dart has thrown for 1,802 yards, 13 touchdowns and 4 INTs on 62.5% passing while also rushing for 400 yards and 7 TDs. Russell Wilson has thrown for 831 yards, 3 touchdowns and 3 INTs on 58% passing and Jameis Winston has 567 passing yards, 2 TDs and 2 interceptions on 56.9% passing. Cam Skattebo also has 410 rushing yards with 5 touchdowns but is out for the year while Tyrone Tracy Jr. has 504 rushing yards and 2 TDs. Wan’Dale Robinson has a team-high 78 catches for 882 yards and 4 TDs while Theo Johnson has 45 grabs for 528 yards and 5 TDs and Darius Slayton has 460 receiving yards as well. On defense, Bobby Okereke has a team-high 117 total tackles including 63 solo tackles. Brian Burns also leads the Giants with 13 sacks as well this season. As a unit, the Giants have combined for 31 sacks and 5 interceptions so far this season.

Minnesota Vikings @ New York Giants Betting Trends: Week 16

Why the New York Giants will win

• The home team has won nine of the Giants’ last 10 Week 16 games.
• The Vikings have lost eight of their last nine road games against NFC East opponents on a losing streak.
• The Giants have covered the spread in seven of their last eight games as underdogs against NFC North opponents.
• The Vikings have failed to cover the spread in five of their last six games following a win.
• The Vikings have lost the first half in four of their last five games as favorites against NFC opponents.
• The Giants have scored the first touchdown in each of their last six games as home underdogs.
• The Vikings have lost the first quarter in each of their last three games as favorites following a win.

Why the Minnesota Vikings will win

• The Vikings have won each of their last 11 games against starting rookie QBs.
• The Giants have lost 17 of their last 18 games against NFC opponents.
• The Vikings have covered the spread in each of their last six games in December.
• The Giants have failed to cover the spread in four of their last five games in December.
• The Giants have lost the first quarter in each of their last 10 December home games against NFC opponents.
• The favorites have won the first half in each of the Vikings’ last 10 Week 16 games.
• The Vikings have scored the first touchdown in each of their last seven games against the Giants.

Total Points Facts

• Each of the last six Sunday games at MetLife Stadium have gone OVER the total points line.
• Eight of the Giants’ last nine games have gone OVER the total points line.
• Each of the Vikings’ last five Week 16 games have gone OVER the total points line.

New York Giants Player Prop Facts

• Jaxson Dart has scored at least one touchdown in each of his last four appearances with the Giants as underdogs against NFC opponents.
• Jaxson Dart has recorded 19+ completions in each of his last three appearances against NFC opponents.
• Devin Singletary has recorded 37+ rushing yards in seven of his eight previous appearances against NFC North opponents.
• Tyrone Tracy has recorded 71+ rushing and receiving yards in each of the Giants’ last four games against NFC opponents.
• Jameis Winston has recorded 277+ passing yards in each of his five previous Week 16 appearances.
• Daniel Bellinger has recorded 15+ receiving yards in each of the Giants’ last six December home games against NFC opponents.
• Heading into Week 16, Brian Burns ranks 2nd in the NFL in sacks (13.0) this season.

Minnesota Vikings Player Prop Facts

• Jordan Mason has scored at least one touchdown in four of the Vikings’ last five games as favorites.
• Aaron Jones has recorded 16+ receiving yards in each of the Vikings’ last 10 regular season road games against NFC opponents.
• Aaron Jones has recorded 67+ rushing yards in six of his last seven Sunday appearances with his team as a road favorite.
• Justin Jefferson has recorded 73+ rushing and receiving yards in each of the Vikings’ last seven games as favorites following a win.
• Heading into Week 16, Max Brosmer has thrown the equal-most interceptions in a single game this season (4 vs Seahawks, Week 13).

Matchup/League Facts

• Giants – six different players have recorded multi-touchdown games this season – equal-most in the NFL, heading into Week 16.
• Giants – four different players have recorded 60+ rushing yards in a game this season – equal-most in the NFL, heading into Week 16.
• Vikings – five different players have recorded 2.0 sacks or more in a game this season – most in the NFL, heading into Week 16.
• Heading into Week 16, the Vikings have recorded the largest margin of victory in the NFL this season (38-points vs Cincinnati on September 21, 2025).

Minnesota Vikings vs. New York Giants Prediction

I’m on the Vikings here. I just feel like every loss hurts the Giants more and more and the Vikings, despite being eliminated from the postseason, look like they’re playing with a lot more pride right now and have shown up to play in the last couple of weeks. I think the Vikings are the better team here and I think on the road, Minnesota gets it done here. Give me the Vikings.

Chris Ruffolo's Pick: Minnesota -2.5